Dr. Akos Koller, MD, PhD, DSc
Professor Emeritus
Semmelweis University, and Hungarian University of Sports Science
Budapest, Hungary and New York Medical College, Valhalla NY, USA
Video Interview with Dr. Akos Koller and Kirk Hamilton PAC 27:42 min:sec
“Multisystem Endothelial Inflammation: A Key Driver of Adverse Events Following mRNA-Containing COVID-19 Vaccines. Vaccines 2025, 13, 855” PDF
Overview…
Dr. Akos Koller, a specialist in microcirculation, discussed the adverse effects of mRNA COVID-19 vaccines, particularly endothelial inflammation caused by the spike protein. He noted that a healthy microcirculation is crucial for recovery from COVID-19 and vaccines. The spike protein from mRNA vaccines is more pathogenic than the natural Covid virus, as it persists longer and can degrade the endothelial glycocalyx, leading to inflammation and vascular injury. Dr. Koller suggested that exercise and products that help restore the glycocalyx might be beneficial in those with post vaccine syndrome (PVS). He also highlighted the individual variability in vaccine responses and the need for personalized medical guidance regarding vaccination and vaccine types.
Things To Be Explored…
Supplements that can help restore glycocalyx, which protect the endothelium from circulating inflammatory cell and thrombus formations and also serve as a permeability barrier.
Conduct biochemical, in vitro and in vivo experiments to see how the spike protein produced by the mRNA vaccines can be broken down.
Encourage exercise and physical activity as a potential intervention for post-vaccination and long COVID syndromes.
Discuss the potential use of blood thinners (anticoagulants) as an adjuvant treatment for post-vaccination syndrome.
Bring together expert panels from various medical societies to review the benefits and risks of COVID-19 vaccines and provide updated, patient-specific (age, gender, race, health conditions, etc.) guidelines.
Dr. Akos Koller’s Background…
Dr. Akos Koller, MD, PhD, is an emeritus professor at Semmelweis University, and Hungarian University of Sports Science, Budapest, Hungary and New York Medical College, Valhalla NY, USA.
Dr. Koller’s background is in microcirculation and his interest in the topic of multi-system endothelial inflammation following mRNA COVID-19 vaccines are highlighted. Dr. Koller explains his background in microcirculation, focusing on very small vessels, such as arterioles, capillaries venules and lymphatics, that support all organs and tissues.
Importance of a Healthy Microcirculation…
He emphasizes the importance of healthy microcirculation in dealing with inflammatory diseases and viruses like COVID-19. Dr. Koller notes that people with pre-existing conditions like diabetes or hypertension were more affected by COVID-19 and post-COVID syndrome. He stresses that healthy microcirculation, especially the endothelium, as a first line of defense is crucial for recovering from diseases and reducing post-vaccination syndrome.
Mechanisms of Inflammation from COVID-19 and mRNA Vaccines…
Kirk Hamilton PA asks about the causes of inflammation from COVID-19 and mRNA vaccines, specifically the role of the spike protein. Dr. Koller explains that mRNA technology involves a liposome membrane package and mRNA that produces the spike protein inside parenchymal (endothelium, skeletal muscle, cardiac muscle, and neural cells etc.) cells. He notes that the mRNA in vaccines is modified to resist enzymatic breakdown, leading to prolonged production of the spike protein. Dr. Koller mentions that individual responses to the vaccine vary, maybe because some people are able to breakdown the mRNA and spike protein faster than others. That is what we should learn.
Comparison of Spike Proteins from Natural Infection and Vaccines…
Kirk Hamilton questions the differences between the spike protein from the natural COVID-19 virus and the one produced by mRNA vaccines. Dr. Koller states that the spike protein from mRNA vaccines is more pathogenic and can spread throughout the body.
He explains that coronaviruses have been present for decades, but the COVID-19 virus from Wuhan was different and caused a “panic” response. Dr. Koller notes that the second or third doses of the vaccine can lead to more adverse effects, and guidelines have been updated to restrict vaccination to certain groups.
Challenges with mRNA Vaccines and Alternative Vaccines…
Kirk Hamilton expresses confusion over why the spike protein, a toxic agent, is used in vaccines. Dr. Koller explains that mRNA vaccines were chosen for their ability to elicit a strong immune response, but they can also cause side effects. He mentions that other vaccines, like the Sinovac’s CoronaVac (COVID-19 vaccine) that used an inactivated virus was made in China do not elicit as strong an immune response but may have fewer side effects. He also mentions the Russian Sputnik, Gam-COVID-Vac (Viral vector vaccines vs. mRNA vaccines: The differences ) and this may deliver less spike protein to the cell. He notes not hearing about significant side effects (spike protein-induced) from these two vaccines.
Dr. Koller suggests that the choice of vaccine should be individualized based on the person’s health status and response to the vaccine.
Mechanisms of Endothelial Inflammation and Importance of the Glycocalyx…
Kirk Hamilton asks how the spike protein causes endothelial inflammation and whether it is worse from the infection or the vaccine. Dr. Koller explains that the spike protein can degrade the glycocalyx, a fine structure on the endothelium that prevents cells from “sticking.” He notes that the glycocalyx is important for maintaining healthy endothelial function and preventing inflammation. Dr. Koller suggests that restoring the glycocalyx could provide a defense against the spike protein.
Potential Treatments and Preventive Measures…
Kirk Hamilton mentions products that enhance the glycocalyx, such as those made from seaweed. (Arterosil is made primarily from rhamnan sulfate, a specialized sulfated polysaccharide extracted from the rare green seaweed, Monostroma nitidum). It also contains a blend of fruit and vegetable extracts rich in antioxidants.
Kirk Hamilton mentions the potential use of enzymes like nattokinase to break down the spike protein and improve endothelial health. Dr. Koller shares that experiments have shown that restoring the glycocalyx with similar molecules can reduce permeability and edema. Dr. Koller emphasizes the importance of individualized treatment and the need for further research on effective interventions.
Personal Experiences and Recommendations…
Kirk Hamilton asks Dr. Koller if he plans to get more mRNA vaccines and whether he encourages his family to get vaccinated. Dr. Koller states that he has not experienced severe illnesses and does not plan to get more vaccines. He mentions that his family members have had different experiences with the vaccine, highlighting the individual variability in response.
Final Thoughts and Closing Remarks…
Dr. Koller recommends exercise and a healthy lifestyle to maintain vascular health and reduce the risk of adverse reactions to vaccines. Dr. Koller stresses the importance of expert consensus in making medical decisions and updating guidelines based on new data. He suggests that the benefits and risks of interventions should be carefully considered and individualized.
Kirk Hamilton asks Dr. Koller who he would recommend getting the COVID vaccine, and Dr. Koller emphasizes the need for expert consultation and individualized decisions. The conversation concludes with Dr. Koller expressing hope for continued collaboration and open discussion in medical research.
Highlights…
COVID 19 VIRUS CREATION HISTORY; PATHOGENICITY OF THE SPIKE PROTEIN CREATED BY THE NATURAL INFECTION VERSUS BY THE mRNA VACCINE; AND TREATMENTS FOR SPIKE PROTEIN DETOXIFICATION - PODCAST INTERVIEW with Peter McCullough, MD. Start at 4:00-58 min:sec. Excellent explanation and historical timeline with practical recommendations for the health professionals and lay public on diagnosis and treatment of “spike protein” illness whether from the natural infection or mRNA Covid 19 vaccine. A “Must Listen.”
NUCLEAR WAR - “Playing Nuclear Roulette”. Tucker Carlson interviews nuclear expert Ivana Hughes from Columbia University. John Leake, Focal Points (Courageous Discourse) Oct 18, 2025. Watch Tucker Carlson Interview with Ivana Nikolić Hughes, PhD who is president of the Nuclear Age Peace Foundation and a Senior Lecturer in Chemistry at Columbia University. She is a member of the Scientific Advisory Group to the Treaty on the Prohibition of Nuclear Weapons. She holds a B.S. with Honors from Caltech and a Ph.D..
Nutrition, Prevention and Integrative Medicine…
ATHEROSCLEROSIS - LIPIDS - NATTOKINASE - Anti-Atherosclerotic Properties of Nattokinase. Widely used product for Spike detoxification has added benefits fighting heart and vascular disease. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Oct 20, 2025.
1) Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants. “..In conclusion, our data demonstrate that atherosclerosis progression and hyperlipidemia can be effectively managed with NK at a dose of 10,800 FU/day… The dose of 10,800 FU/day is safe and well tolerated. Some lifestyle factors and the coadministration of vitamin K2 and aspirin lead to improved outcomes in the use of NK. Our findings provide clinical evidence on the effective dose of NK in the management of cardiovascular disease and challenge the recommended dose of 2,000 FU per day…”
2) A clinical study on the effect of nattokinase on carotid artery atherosclerosis and hyperlipidaemia."“…Our findings…suggests that daily NK supplementation is an effective way to manage the progression of atherosclerosis and potentially may be a better alternative to statins...”
3) Nattokinase atherothrombotic prevention study: A randomized controlled trial. “…Results of this trial show that nattokinase supplementation has a null effect on subclinical atherosclerosis progression in healthy individuals at low risk for CVD…” Nattokinase dose was 2000 U per day.
4) Research Progress of Nattokinase in Reducing Blood Lipid. “…Natto is a traditional Japanese fermented food, which is made from soybeans fermented by Bacillus natto. During the fermentation process, natto will produce a variety of biologically active substances, including nattokinase…Large-scale clinical trials have confirmed that nattokinase significantly improves the lipid profile and reduces the atherosclerotic plaque area and intima-media thickness with a favorable safety profile…”
BLOOD SUGAR - SQUATS - Squats vs. Walking: Science Reveals The Unexpected Winner For Blood Sugar, By Ava Durgin, MindBodyGreen, September 08, 2025.
1) Enhanced muscle activity during interrupted sitting improves glycemic control in overweight and obese men. “…Collectively, short, frequent walking or squatting breaks effectively enhance glycemic control in overweight and obese men compared to a single bout of walking within prolonged sitting…”
COGNITION - FLAVONOLS - Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities.
1) Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities. “…dietary intakes of total flavonols and several flavonol constituents may be associated with slower decline in global cognition and multiple cognitive abilities with older age…”
GENES - KINDNESS - How Kindness Can Enhance Your Life—And Your Genes. Kindness begins with empathy, activating brain circuits that mirror others’ feelings and foster compassion. By Makai Allbert, EPOCH Times, October 18, 2025.
1)What is Unique About Kindness? Exploring the Proximal Experience of Prosocial Acts Relative to Other Positive Behaviors. “…These results illuminate the experience of positive eudaimonic feelings while one commits kind acts for others and highlight the unique benefits of prosociality compared to other positive behaviors…”
2) The genomic impact of kindness to self vs. others: A randomized controlled trial.
”…In the present study, community-dwelling adults who were randomly assigned to perform kind acts directed toward specific other individuals showed significant declines in leukocyte CTRA gene expression over as 5-week period…”
3) Kindness in the blood: A randomized controlled trial of the gene regulatory impact of prosocial behavior. “…In a randomized controlled experiment, people who performed kind acts for others showed favorable changes in immune cell gene expression profiles…”
3) A little thanks goes a long way: Explaining why gratitude expressions motivate prosocial behavior. “…Gratitude expressions increase prosocial behavior by enabling individuals to feel socially valued…”
4) Cooperative behavior cascades in human social networks. “…The results suggest that each additional contribution a subject makes to the public good in the first period is tripled over the course of the experiment by other subjects who are directly or indirectly influenced to contribute more as a consequence…”
5) Meditation Increases Compassionate Responses to Suffering.
6) Mindfulness and Compassion: An Examination of Mechanism and Scalability.”…As predicted, participants assigned to the mindfulness meditation condition gave up their seats more frequently than did those assigned to the active control group…”
7)Awe, the Small Self, and Prosocial Behavior. “…By diminishing the emphasis on the individual self, awe may encourage people to forego strict self-interest to improve the welfare of others. Future research should build on these initial findings to further uncover the ways in which awe shifts people away from being the center of their own individual worlds, toward a focus on the broader social context and their place within it…”
Kirk’s Comment: Kindness is good for our genes, for our personal health and the planet.
PNEUMONIA - PNEUMOCOCCAL PNEUMONIA - 2.23 Million-Person Study Finds Pneumococcal Vaccines Increase Risk of Pneumonia and Death. The vaccines given to nearly every U.S. child and senior were linked to higher pneumonia and death rates in one of the largest real-world studies ever conducted. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse, Oct 22, 2025.
1) Real world effectiveness of antipneumococcal vaccination against pneumonia in adults: a population-based cohort study, Catalonia, 2019. “…This study did not find evidence of the clinical effectiveness of PPsV23/PCV13 vaccination in preventing the outcomes measured at population-based level…”
SWEATING - HEALTH BENEFITS - COVID 19 - Health Benefits of Sweating. Embarrassing perspiration has many redeeming properties. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Oct 22, 2025.
1) Excretion of Ni, Pb, Cu, As, and Hg in Sweat under Two Sweating Conditions.
2) Human Excretion of Bisphenol A: Blood, Urine, and Sweat (BUS) Study.
3) Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review. “…Regular dry sauna bathing has potential health benefits…”
4) Current state of knowledge on the excretion of mRNA and spike produced by anti-COVID-19 mRNA vaccines; possibility of contamination of the entourage of those vaccinated by these products. “…There are many testimonies of non-vaccinated persons who experienced symptoms identical to the adverse effects of the vaccine after having been in contact with freshly vaccinated persons. A study shows an excess of mortality in the non-vaccinated age groups when vaccination campaigns begin, which could be explained by a phenomenon of transmission of the vaccine or its products…”
VACCINES - SHINGLES - Shingles Vaccine Theoretical Efficacy Down to 56%. Enthusiasm Dropping as More Shingles Pop Up in Vaccinated. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Oct 19, 2025.
1) Effectiveness of Recombinant Herpes Zoster Vaccine in the U.S. Medicare Population, 2018 to 2019, by Immunocompetence and Prior Receipt of Live Zoster Vaccine.
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Cancer…
COLON CANCER - METASTASIS - SUGAR SWEETENED BEVERAGES (SSBS) - Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD
“…The consumption of sugar-sweetened beverages (SSBs), which contain high levels of fructose and glucose, has been causally and mechanistically linked to an increased risk of colorectal cancer (CRC)… Our findings highlight the detrimental impact of SSBs on CRC progression and suggest potential dietary and therapeutic strategies to mitigate metastasis in patients with CRC…”
ESOPHAGEAL CANCER - IVERMECTIN and FENBENDAZOLE Testimonial - 37 year old Tasmania, AUSTRALIA man with Esophageal Cancer becomes cancer free after only 2 months! William Makis, MD, Covid Intel Sep 19, 2025.
MELANOMA - IVERMECTIN and MEBENDAZOLE Testimonial - 69 year old man from Peru with Stage 4 Melanoma (Anorectal) reports after 4 months - dramatic improvement in quality of life! William Makis, MD, Covid Intel, Oct 14, 2025.
Covid Syndrome…
COVID 19 VACCINATION - DNA CONTAMINATION - DNA Inside COVID Shots: Independent Science Confirms What Regulators Ignored. Peer-reviewed study by independent scientists finds plasmid DNA—incl. SV40 enhancers—inside COVID shots. Join host Dr. Ryan Cole as our experts reveal risks, regulatory silence, and what happens next. Independent Medical Alliance, Jessica Rose, Sep 19, 2025.
1) Quantification of residual plasmid DNA and SV40 promoter-enhancer sequences in Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada. “…When tested by qPCR, all Moderna vials were within the regulatory limit, but 2/6 Pfizer lots (3 vials) exceeded the regulatory limit for the SV40 promoter-enhancer-ori by 2-fold. The presence of the SV40 promoter-enhancer element in Pfizer vials raises significant safety concerns. This study emphasizes the importance of methodological considerations when quantifying residual plasmid DNA in modRNA products, considering increased LNP transfection efficiency, and cumulative dosing presents significant and unquantified risks to human health…”
Practice, Persistence and Patience - My Favorite. The first story of transformation that “jumped out” at me before my cancer and then the first one “sent” to me after my cancer diagnosis. A physician cures herself of a rare, life threatening sarcoma after chemo, radiation and alternative therapies had been tried.
”Source” the Documentary - The Science behind the practice. Highly recommended.
Proof - Stories of Transformation (listen to a few stories of transformation from serious health problems)
Research: The Science Behind Mind/Body Healing and Meditation
Dr. Joe Dispenza’s Book: Becoming Supernatural
Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class
Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
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www.HealthyLivingforBusypeople.com
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