Do Patients With Endometriosis Have Impaired Intestinal Permeability An Interview with Surgeon Shanti Mohling

Do Patients With Endometriosis Have Impaired Intestinal Permeability Compared to Healthy Controls and Patients with Pelvic Pain Without Endometriosis?

Substack Video Kirk Hamilton PAC Interview Shanti Mohling, MD 46:36 min:sec
Shanti Mohling, MD, FACOG
Northwest Endometriosis and Pelvic Surgery
511 SW 10th Ave, Suite 907, Portland, OR 97205
503-715-1377 / Fax 503-715-2717
Shantimohling@gmail.com

“Intestinal permeability and endometriosis: a pilot investigation ”
Journal of Endometriosis and Uterine Disorders,
September 2023, Volume 3,100045 9/2025
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Kirk’s Comments on Interview…

Fond Memories of the Power of Food Elimination…
I was very excited about this interview because it reinforced a major belief and long-standing practice of mine as an integrative medicine physician assistant: that individual foods—or patterns of food consumption—can cause virtually any symptom, symptom complex, or systemic disease.

This understanding dates back to my very first job as a physician’s assistant in an integrative medicine practice in May 1983, where nearly every patient was placed on a two-week “detox.” The protocol consisted of a green smoothie (with psyllium seed husks and basic vitamins) and daily coffee enemas to “stimulate” liver detoxification. Nothing else was eaten. I remember it well—it was a kind of slimy, green drink.

The bottom line was simple: patients were removed from their usual food patterns. Most patients came in with multiple complaints, often linked to unhealthy diets. Or others ate what seemed like a pristine diet but regularly consumed one or two foods that “looked healthy” but triggered sensitivity—such as eggs, sprouted grain bread, sourdough, yogurt or coffee (it could be any frequently eaten whole food…). One person’s health food could easily be another’s source of chronic symptoms.

In just six months at that practice, I witnessed nearly every patient experience improvements in their symptoms or disease complex during or after this two-week elimination diet. It didn’t matter what their initial complaints were—almost always, something improved.

Working Hypothesis…
My working hypothesis is that removing the patients “normal foods” (some offending?) gave the gut time to heal. Most gut cells from the stomach to rectum take somewhere between 3–7 days to regenerate. Intestinal permeability can improve from weeks to months. I suspect that excessive antigen uptake that fuels immune activation was reduced immediately by eliminating commonly eaten offending foods, and, over time as intestinal permeability was reduced. This “quieted” the immune system and lead to symptom relief—sometimes immediately, sometimes after weeks or months on a low “food intolerance” regimen.

The “magic” wasn’t just in food removal; it was in the gut’s opportunity to repair itself. Depending on diet and fiber intake, the microbiome (intestinal bacteria) can take months to re-balance which is where systemic disease can be slowed, stopped or even reversed.

What Do Food Sensitivities or Diet Have to Do with Endometriosis?…
This experience is directly relevant to Dr. Mohling’s research. She and her colleagues found a significantly higher degree of intestinal permeability in patients with endometriosis compared to those with pelvic pain alone or healthy controls.

This suggests that food—directly or indirectly, through intestinal permeability and microbiome disruption—“may” play a role in triggering or healing endometriosis (or symptom reduction) in susceptible individuals.

The key question is whether increased intestinal permeability precedes endometriosis or is a consequence of the disease. It may be both: a contributing factor and a byproduct, creating a vicious cycle.

Endometriosis Tissue: Similar but Not the Same…
Dr. Mohling explained a compelling hypothesis: that endometrial-like tissue outside the uterus may originate during gestation. This tissue is similar to, but not identical with, uterine endometrial lining. When exposed to inflammatory cytokines, it can become symptomatic endometriosis in and around the abdominal cavity and organs.

Rather than relying solely on the retrograde menstruation theory, this explanation offers a clearer mechanism: physiologic events such as increased intestinal permeability or altered microbiota may drive inflammation that stimulates these ectopic tissues.

Kirk’s “Mile High View”…
The bigger picture is that intestinal permeability and microbiome disruption may underlie not only endometriosis but also many chronic systemic illnesses. The specific symptoms differ, but the pathophysiology is similar: food (or medication) consumption → increased intestinal permeability → microbiome disruption → inflammatory mediator release → chronic disease.

So, while Dr. Mohling’s findings are directly relevant to endometriosis, they also apply broadly to many chronic conditions that conventional medicine struggles to manage.

That said, Dr. Mohling is clear: for significant endometriosis, surgery is usually necessary to achieve meaningful symptom relief. Lifestyle measures are supportive but rarely sufficient on their own.

Lifestyle Strategies for Endometriosis…
In addition to a whole-food diet rich in fruits, vegetables, protein, and cultured dairy, Dr. Mohling recommends:

  • Vitamins C, D, and E

  • NAC (N-acetylcysteine)

  • Omega-3 fatty acids

  • Magnesium

  • Probiotics

  • Palmitoyl ethanolamide (PEA) — which Dr. Mohling was particularly enthusiastic about

I would also suggest:

  1. Assessing for bacterial or yeast/fungal overgrowth, or doing a therapeutic antifungal trial over 2-4 weeks if indicated by extensive antibiotic history.

  2. Incorporating periodic fasting, such as the Prolon Fasting Mimicking Diet (five days a month for 6–12 months) to reduce immune activation and inflammatory mediators.

  3. Considering supervised water fasting programs at centers like TrueNorth Health Center for carefully selected patients for 1-2 weeks.

Kirk Hamilton PA-C

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Otter.AI Generated Interview Transcript Summary

Overview…
Dr. Shanti Mohling, an OB-GYN surgeon, discussed her study on intestinal permeability in patients with endometriosis, published in the Journal of Endometriosis and Pelvic Pain Disorders. The study found that 50% of endometriosis patients had intestinal permeability, compared to none in healthy controls and 10% in those with pelvic pain but no endometriosis. Dr. Mohling emphasized the importance of lifestyle changes, including a diet rich in fruits, vegetables, and lean proteins, and the use of supplements like omega-3, vitamin D, and NAC. She also highlighted the need for surgery to manage endometriosis effectively.

Introduction and Background of Dr. Shanti Mohling…

  • Kirk Hamilton introduces himself and the show’s focus on endometriosis and intestinal permeability.

  • Dr. Shanti Mohling, an OB-GYN surgeon, is introduced as the guest.

  • Dr. Mohling shares her background, including her education in massage therapy and her transition to medical school.

  • Dr. Mohling discusses her current focus on surgical management of endometriosis in Portland, Oregon.

Understanding Endometriosis and Its Etiology…

  • Dr. Mohling explains the etiology of endometriosis, emphasizing that it is not fully understood.

  • She describes the theory of retrograde menstruation and the role of unhealthy peritoneal fluid in endometriosis.

  • Dr. Mohling highlights the importance of a healthy internal environment in managing endometriosis.

  • Kirk Hamilton asks for clarification on endometriosis, and Dr. Mohling explains the process of endometrial tissue possibly migrating outside the uterus and/or the endometrial-like tissue was already present outside the uterus but do to multiple triggering factors caused the manifestation of the disease which could be the result of increased intestinal permeability or the disease process might increase intestinal permeability.

Intestinal Permeability and Endometriosis…

  • Dr. Mohling discusses her study on intestinal permeability and endometriosis, noting that half of the patients with endometriosis also had increased intestinal permeability.

  • She explains that intestinal permeability can be transient and can improve with dietary changes.

  • Dr. Mohling emphasizes the association between intestinal permeability and endometriosis, but not the causality.

  • Kirk Hamilton and Dr. Mohling discuss the inflammatory nature of endometriosis and its impact on pain.

Prevalence and Impact of Endometriosis…

  • Dr. Mohling estimates that 10% of females have endometriosis, which can range from mild to severe.

  • She describes the debilitating effects of endometriosis, including severe dysmenorrhea, infertility, and fibrotic lesions.

  • Dr. Mohling explains how endometriosis can manifest with IBS-like symptoms and debilitating cramping pain.

  • Kirk Hamilton asks about the symptoms of endometriosis, and Dr. Mohling emphasizes the importance of recognizing severe menstrual cramps, especially those that result in an emergency room visit for pain control.

Lifestyle and Dietary Recommendations for Endometriosis

  • Dr. Mohling recommends a diet rich in fruits, vegetables, and lean proteins to improve gut health and manage endometriosis.

  • She advises limiting processed foods, sugar, and alcohol to support gut health.

  • Dr. Mohling discusses the importance of a balanced diet, including moderate dairy products and cultured dairy.

  • She highlights the role of supplements like omega-3 fatty acids, vitamin D, vitamin C, and NAC in managing endometriosis.

Role of Surgery and Lifestyle Changes in Managing Endometriosis

  • Dr. Mohling emphasizes the importance of surgery in removing endometriotic lesions but also stresses the need for lifestyle changes.

  • She discusses the impact of long-term use of NSAIDs and the development of intestinal permeability.

  • Dr. Mohling mentions the role of the microbiome in estrogen metabolism (recycling and resorption of estrogen) and its impact on endometriosis.

  • Kirk Hamilton and Dr. Mohling discuss the potential benefits of fasting and dietary interventions like the fasting-mimicking diet.

Challenges and Controversies in Endometriosis Treatment…

  • Dr. Mohling discusses the limitations of hormonal treatments like birth control pills and hormone blockers.

  • She highlights the importance of excising endometriotic lesions to manage pain and improve quality of life.

  • Dr. Mohling shares her experience with patients who have been misdiagnosed or undertreated for endometriosis.

  • Kirk Hamilton and Dr. Mohling discuss the role of physical therapists in referring patients with pelvic pain to specialists.

Future Research and Personal Insights…

  • Dr. Mohling mentions her ongoing work on a book that bridges the concepts of surgical management and lifestyle changes for endometriosis.

  • She discusses the potential impact of COVID-19 on endometriosis symptoms but notes the lack of definitive evidence.

  • Dr. Mohling reflects on the evolution of endometriosis treatment and the importance of early diagnosis and comprehensive care.

  • Kirk Hamilton and Dr. Mohling conclude the interview with mutual appreciation for their shared commitment to integrative and lifestyle medicine.

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    Highlights…

SSRIS – ANTIANXIETY MEDICATIONS – SIDE EFFECTS – SSRIs and School Shootings, FDA Corruption, and Why Everyone on Anti-Depressants Is Totally Unhappy. Aug 29, 2025 The Tucker Carlson Show Interview with former FDA Medical Officer, Psychiatrist Josef Witt-Doerring, Medical Director of TaperClinic
Aug 29, 2025 The Tucker Carlson Show Aug 29, 2025 The Tucker Carlson Show
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11:03 The “Chemical Imbalance” Lie
15:03 Why Is Depression Rising?
22:36 The Dark Truth Dr. Witt-Doerring Uncovered While Studying Psychiatry
29:05 The Corruption of the FDA
39:32 The Untold Side Effects of SSRIs
54:30 The Testimonies of People Impacted by These Side Effects
103:45 Is There a Link Between SSRIs and Mass Shootings?
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1:20:32 What Is ADHD?
1:25:10 The Truth About Cannabis
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1:35:18 How Do SSRIs Impact Relationships?
1:40:46 The Telehealth Scam Taking Over the Country
1:44:13 The Scary New Law Pushing Drugs on Children
1:47:09 Dr. Witt-Doerring’s Advice to Someone Suffering From Depression
1:51:00 Why the Establishment Thinks Dr. Witt-Doerring Is Dangerous

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HEART FUNCTION – A Quiet Medicine: How Silence Slows Down Your Heart and Grows Neurons. The absence of sound speaks volumes.
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10)Correlates of Silence: Enhanced Microstructural Changes in the Uncinate Fasciculus.
11) Silence is golden: Extended silence, deliberative mindset, and value creation in negotiation.
12) Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non-musicians: the importance of silence.

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1) RESOLUTION 2000-1: AAPS Resolution on Mandatory Vaccines.

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Cancer…

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1) COVID-19 vaccination, all-cause mortality, and hospitalization for cancer: 30-month cohort study in an Italian province.

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1) “COVID-19 mRNA vaccines can induce cancer in 17 distinct ways, according to over 100 studies”

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Covid Syndrome…

COVID VACCINATION – AUTOIMMUNITY – Long-term risk of autoimmune diseases after mRNA-based SARS-CoV2 vaccination in a Korean, nationwide, population-based cohort study. “…We report that the risk of developing most AI-CTDs did not increase following mRNA vaccination, except for systemic lupus erythematosus with a 1.16-fold risk in vaccinated individuals relative to controls… However, a booster vaccination was associated with an increased risk of some AI-CTDs including alopecia areata, psoriasis, and rheumatoid arthritis. Overall, we conclude that mRNA-based vaccinations are not associated with an increased risk of most AI-CTDs, although further research is needed regarding its potential association with certain conditions…”

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Societal and World Health…

PARENTAL RIGHTS – HEALTHCARE BILL OF RIGHTS – IMA Launches Parents’ “Back to School” Healthcare Bill of Rights. The Independent Medical Alliance has launched a Parents’ Healthcare Bill of Rights just in time for back-to-school, restoring parental authority over kids’ health and education. Independent Medical Alliance, Aug 26, 2025.

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Did The Covid Vaccine Increase Mortality from All Causes Compared to Those Not Vaccinated Between April 21 and May 2023 in England?

An Interview With Jarle Aarstad, PhD

Jarle Aarstad, PhD
Western Norway University of Applied Sciences
Bergen, Norway
jarle.aarstad@hvl.no
(8/2025)

“Mortality involving and not involving COVID-19 among vaccinated vs. unvaccinated in England between Apr 21 and May 23.” F1000Research 2025, 14:133. (article accessed here) PDF Abstract
Kirk Hamilton PAC’s YouTube Commentary 9:16 sec:min

Previously titled: “The temporal protection and declining health of the COVID-19 vaccinated in England: A 26-month comparison of the mortality involving and not involving COVID-19 among vaccinated vs. unvaccinated.”

Kirk Hamilton: Can you please share with me your educational background and current position?

Jarle Aarstad: I am an economist with a PhD in business administration from the NHH Norwegian School of Economics. Now I am a full professor at Western Norway University of Applied Sciences, formally in innovation and entrepreneurship, with numerous publications, including in leading journals. Mostly, I use quantitative methodologies. Over the past few years, my research focus has shifted towards topics related to COVID-19 and vaccination, utilizing similar quantitative approaches.

KH: What got you interested in studying the mortality difference between the Covid vaccinated and non-vaccinated during the time period of April 2021 to May 2023?

JA: I had conducted country-level studies on vaccination and excess mortality, and I was interested in examining whether person-level data publicly available aligned with my previous research findings. Apr 21 to May 23 is the whole period for which the data are publicly available. If the period were extended, of course, I would include them in my study – the more data, the better. Having said that, the period available gives a fairly good insight into what happened in the aftermath of the vaccine rollout.

KH: Can you tell us about your study and the basic results?

JA: The study compared monthly mortality rates among vaccinated and unvaccinated individuals aged 10 years and older in England during the specified period. In my study, vaccinated individuals were those who had received at least one dose. The data provided is age-standardized, meaning that different age distributions among vaccinated and unvaccinated individuals are accounted for. However, observing differences in mortality may nonetheless be attributed to vaccine hesitancy, which raises concerns. That is, those not taking the vaccine may likely have inferior health at the outset, which can complicate isolating a genuine vaccine effect. To address the issue, I decided to compare all-cause mortality and mortality excluding COVID-19. (access article and figures here) Figure 1A particularly at the beginning of the period shows relatively high mortality among unvaccinated, but as the pattern is similar in Figure 1B concerning mortality not involving COVID-19, a large chunk of the difference can be attributed to unvaccinated having inferior health at the outside (the basic argument in that the vaccine cannot prevent mortality not involving COVID-19). Having said that, comparing the results from those figures, Figure 2A shows that the all-cause mortality, i.e., mortality including COVID-19 (between unvaccinated vs. vaccinated) was higher than mortality not involving COVID-19 (between unvaccinated vs. vaccinated) between July 21 and Jan 22 (the green vs. the orange plot). Having said that, there is a steady decrease in mortality among the unvaccinated compared to the vaccinated (best illustrated in Figure 3), or in other words, a steady increase in mortality among the vaccinated compared to the unvaccinated. I cannot find another explanation than the vaccine inducing a long-term increase in mortality. Together, the vaccines may have limited the relative increase in mortality among vaccinated individuals for a short period, but the overall trend points in a negative direction.

KH: Did you expect to see a reduction in mortality from Covid initially in the Covid vaccinated group?

JA: According to other research, which claims a temporal protective effect, yes. Nation-level analyses I have done show similar trends during the same period (but I have started doubting my previous conclusions, which is a topic for a study I am currently working on).

KH: Can you explain why difference in mortality might have not been do to the Covid vaccine protection but the poorer initial health of the non-vaccinated?

JA: As Figure 1B excludes mortality related to COVID-19, the only reason for the difference, particularly at the beginning of the period, in my opinion, is that unvaccinated individuals initially had poorer health. That we also know from other research. In Norway, 30% lower mortality among young vaccinated compared to unvaccinated people cannot be attributed to the vaccine since practically zero young people have died from COVID-19 here.

KH: When did you notice those vaccinated started having an increase in overall mortality from all causes?

JA: In Figure 3, you can observe that it increased among vaccinated individuals from the beginning of the period and decreased among unvaccinated individuals (possibly before, but I don’t have data). On the conservative end, the first months may have been outliers, but the overall trend is nonetheless as reported.

KH: How do your findings reflect on the overall mortality increase in those who took the Covid vaccine? Is the vaccine the probably causative agent?

JA: The vaccine is probably the causative agent, or at least, I cannot find other plausible explanations for the trends observed in Figs. 2A and 3 (the rollout may theoretically explain it, but I have discussed that). As the period followed an earlier period of excess mortality, one would expect a decrease in mortality; however, this is only observed among the unvaccinated.

KH: If this observation is correct of increased overall mortality in those vaccinated with limited benefit of the vaccine it sounds like the Covid vaccine is something that should not be implemented?

JA: I agree with you. The vaccine has caused substantial harm, with very few, if any, benefits.

KH: Do you have any idea of the causative agent (s) in the Covid vaccine that may be causing an increase in overall mortality (i.e. altered spike protein delivered via lipid nanoparticles being produced for an in-determinant amount of time causing inflammation to vascular, neuronal, reproductive and oncogenic susceptible tissues, or viral contaminants, etc.)

JA: As an economist, an expert in numbers but not specifically in medical issues, I leave that issue to other experts.

KH: Do we know how long the spike protein remains in the body?

JA: Again, I leave that for other experts.

KH: How would you further study this topic to corroborate your concerning findings.

JA: I have studied international data (from 39 countries with more than one billion people) that I have followed over three years, from 2021 to 2023, as well as US county data (with over 2000 observations) that I have also followed over the same period. Additionally, I conducted a study on young people in England, which revealed a significant increase in deaths in the weeks following vaccination. The pattern was similar for each dose.

KH: Thank you for your time and excellent science and courage to publish these findings. I look forward to sharing your future studies on this critically important subject.

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Highlights…

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1) Dietary intake of tomato and lycopene, blood levels of lycopene, and risk of total and specific cancers in adults: a systematic review and dose–response meta-analysis of prospective cohort studies.
2) Complementary and Alternative Medicine for Advanced Prostate Cancer.
3) Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications.
4) More evidence that physical activity is beneficial for prostate cancer.
5) Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth.
6) Role of zinc homeostasis in the prevention of prostate diseases.
7) Serum Insulin, Glucose, Indices of Insulin Resistance, and Risk of Prostate Cancer.
8) Chronic Stress Promotes Cancer Development.
9) Chronotype, sleep timing, sleep regularity, and cancer risk: A systematic review.
10) Endocrine disruptors and prostate cancer risk.
11) Selenium and Vitamin E Cancer Prevention Trial (SELECT): Questions and Answers.
12) Association Between Red and Processed Meat Consumption and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis.
13) Prostate Cancer Risk Factors.

VACCINATION – CDC Sued for Pushing Illegal 72-Dose Childhood Vaccine Schedule. CDC accused of running an illegal and unconstitutional hyper-vaccination program — never once tested for cumulative safety. Nicolas Hulscher, MPH. Focal Points (Courageous Discourse, Aug 18, 2025.

VACCINATION – HEALTH AND HUMAN SERVICES – HEALTH CANADA – The Vaccine Cartel Strikes Back. American Academy of Pediatrics pushes mRNA shots for babies against HHS guidance — as Health Canada approves Pfizer’s LP.8.1 mRNA injection for infants. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Aug 19, 2025.

VACCINATION – EXEMPTIONS – INCREASING – Vaccination Coverage and Exemptions among Kindergartners. Report from CDC Indicates Increasing Numbers of Parents Filing Exemptions. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Aug 18, 2025.
1) Vaccination Coverage and Exemptions among Kindergartners, July 31, 2025.

VACCINATION – FLU – COVID STROKE – U.S Government Researchers Warn of Elevated Stroke Risk After Covid and Flu ‘Vaccine’ Co-Administration Dr. William Makis MD, Aug 21, 2025.
1) A Three-Part Model for the Self-Controlled Case Series Design to Estimate and Characterize, Adverse Event Risk in an Overlapping Risk Period after Multiple Vaccines: Application to Ischemic Stroke Following Pfizer-BioNTech Bivalent COVID-19 Vaccine and Influenza Vaccine.
1) Effectiveness of the Influenza Vaccine During the 2024-2025 Respiratory Viral Season. (Conclusion: Influenza vaccine in-effective )

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for the full content of this SUBSTACK’S POST
on “Cancer and covid syndrome” CLICK HERE

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Societal and World Health…

FORCED ORGAN HARVESTING – REWARDS – CONGRESS – CCP’s New Push to Eliminate Falun Gong and Shen Yun Globally.
1) Congressmen Urge State Department to Combat China’s Forced Organ Harvesting with Rewards for Information – Letter to Secretary of State Marco Rubio.

PANAMA CANAL – CHINA BRIDGE CONSTRUCTION – Panama Canal 13 August 2025 — China Continues to Build Bridge. Big Regional Fight Unfolding. Michael Yon, Michael’s Newsletter, August 13, 2025. Another Chinese Bridged Collapses……while China Builds Another Bridge over PANAMA CANAL, Michael Yon, Michael’s Newsletter, Aug 24, 2025.

_____________________________________________________________________________

Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Intergenerational Day Centers: A New Wave in Adult and Child Day Care an Interview with Dr. Neda Norouzi, PhD ___________________________________________

From Loving Great Grandparents and Memories, to Working in Daycare, to Studying Architecture Helping Answer a Need for Taking Care of the Elderly and Children and Benefiting Both in the Process... (Video Interview)

Intergenerational Day Centers: A New Wave in Adult and Child Day Care
and Interview with Dr. Neda Norouzi, PhD

Neda Norouzi, PhD, M.Arch, MURP, B.Env.D
School of Architecture + Planning
The University of Texas at San Antonio
San Antonio, TX 78703, neda.norouzi@utsa.edu

“Intergenerational Day Centers: A New Wave in Adult and Child Day Care. Int J Environ Res Public Health. 2023 Jan 1;20(1):809. Abstract

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Kirk’s Comments: I was first intrigued by this article by the possible positive health aspect for both age groups but, especially the elderly interacting together. From reading about Blue Zone cultures to my own experiences with my grand children being around youth and young life can keep you thinking and acting younger and challenging you in life giving ways.

Then after reading about Dr. Norouzi’s background as an architect and education in urban planning I thought do we really want municipalities and local governments to fund and implement such facilities. I have concerns about governmental waste and bureaucracy and the safety concerns of the young children around adults. I ask about them in the interview.

If I was going to have a person try and put together such a facility and program in a private business or municipal setting Dr. Neda Norouzi checks all the “positive” boxes of someone who could do this with multidimensional expertise.

First her love of family and her “great” grandparent stories and love of children let you know right off how she values family. After she immigrated to this country she worked in daycare for years. Then she has all the academic credentials for urban planning and architecture. And because of her passion for the topic she is the perfect person to oversea such an endeavor. A very interesting topic. I hope you enjoy our conversation.

Kirk

(Otter.Ai Generated Summary of Interview Transcript)

Intergenerational Day Centers: Introduction and Guest Background

  • Kirk Hamilton introduces the topic of intergenerational day centers and his guest, Dr. Neda Norouzi, a PhD from the University of Texas at San Antonio.

  • Dr. Norouzi shares her educational background, starting from her birth in Iran, her move to the U.S., and her initial job at a daycare center.

  • She discusses her transition from child development courses to studying architecture and urban planning, influenced by her interest in solving public problems.

  • Dr. Norouzi explains her master's thesis on intergenerational programs, inspired by her personal experiences with her great-grandparents.

Personal Experiences and Research Journey

  • Dr. Norouzi recounts her experiences with her great-grandparents in Iran, which influenced her interest in intergenerational design.

  • She describes her master's thesis on intergenerational programs and how it led to her job in DC and further research.

  • Dr. Norouzi shares her journey to obtaining a PhD in architecture, focusing on intergenerational design, and her involvement with Generations United.

  • She highlights the importance of understanding the client-designer relationship and the impact of her research on designing for intergenerational centers.

Benefits of Intergenerational Programs

  • Kirk Hamilton and Dr. Norouzi discuss the benefits of intergenerational programs for both the elderly and children.

  • Dr. Norouzi emphasizes the energy and physical activity that older adults experience when interacting with children.

  • She notes the cognitive benefits for older adults, such as improved memory and cognitive functions.

  • For children, Dr. Norouzi highlights the love and unconditional support they receive from older adults, as well as the academic and social-emotional skills they develop.

Designing Intergenerational Centers

  • Dr. Norouzi explains the importance of designing intergenerational centers that facilitate organic interactions between children and older adults.

  • She discusses the challenges of integrating intergenerational activities into existing facilities and the need for dedicated spaces.

  • Dr. Norouzi shares examples of successful intergenerational centers and the types of activities that are conducted.

  • She emphasizes the need for flexible designs that allow for different levels of interaction and the importance of supervision to ensure safety.

Challenges and Future of Intergenerational Centers

  • Dr. Norouzi addresses the challenges of implementing intergenerational centers, including the need for city involvement and funding.

  • She discusses the potential for private businesses to see the benefits of intergenerational centers and invest in them.

  • Dr. Norouzi shares her vision of having intergenerational centers become a common feature in every city.

  • She reflects on the importance of these centers in a society where families are often geographically dispersed, providing non-familial interactions that foster understanding and connection between generations.
    _______________________________________________________________________

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Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

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___________________________________________________________________________

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

What is the Evidence and Possible Mechanisms of How Meditation Can Change Our Biology and Health

Hemal H. Patel, PhD
Professor & Vice-Chair for Development and Advancement
Director, UCSD Cardiac/Neuro Protection Laboratories
VA Research Career Scientist, VA San Diego Healthcare System
Video Interview
Department of Anesthesiology, University of California, San Diego
Biomedical Sciences Building, Mail Code 0629, 9500 Gilman Drive
La Jolla, CA 92093-0629. e-mail: hepatel@ucsd.edu (08/13/25)

Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease. Brain Behav Immun Health. 2023 Aug 7;32:100675. PDF

Key Findings…

  • Length of meditation practice may influence susceptibility and management of COVID-19.

  • Blood plasma from mediators can limit viral infection in cultured lung cells.

  • Meditation elevates SERPINA5, a major player in coagulation and the immune response.

  • Regular meditation practice can improve well-being by modulation of biological processes.

“Multidimensional Analysis of Twin Sets During an Intensive Week-Long Meditation Retreat: A Pilot Study,” Mindfulness (N Y). 2025;16(6):1634-1655. PDF

Key Findings…

  • Meditation may increase a family of proteins called “plasmalogens” that act as antioxidants – which protect us from a number of chronic diseases and have an anti-aging effect.

  • Meditation may increase tryptophan metabolism. This leads to the production of serotonin – a vital mood regulator; and melatonin – a hormone that regulates the sleep-wake cycle.

  • Meditation may elevate proteins in the blood that lead to tissue repair and regeneration.
    _________________________________________________________________________

    (Otter.Ai Generated Summary of Partial Transcript)

    Initial Research Findings and Personal Experiences

    Dr. Patel shares his initial skepticism and eventual participation in meditation events, which led to significant personal and professional insights.

    He describes the unique research environment at meditation events, where participants are controlled for various factors, making it easier to study biological changes.

    Dr. Patel highlights the dramatic biochemical shifts observed in novice meditators compared to experienced meditators and controls.

    He discusses the potential for meditation to impact a wide range of diseases, drawing parallels to the development of pharmaceutical drugs for specific diseases.

    Biological Measurements and Data Collection

    Dr. Patel explains the comprehensive data collection at meditation events, including wearable devices, blood samples, saliva, and stress markers.

    He describes the use of video diaries to capture participants' facial expressions and speech, which can be analyzed for changes in biology.

    Dr. Patel discusses the goal of providing biofeedback to participants, allowing them to monitor their meditation practices and health.

    He highlights the unexpected prevalence of mental health and other diseases among meditation event participants, suggesting a broader impact of meditation on health.

    Meditation and Biological Changes

    Dr. Patel elaborates on the biological changes observed in meditation participants, including shifts in the microbiome, heart rate variability, and brainwave patterns.

    He describes the concept of the "human collectome," encompassing all measurable biological factors in an individual.

    Dr. Patel discusses the potential for meditation to create a synergistic effect when combined with Western medical treatments, such as chemotherapy for cancer.

    He shares his personal approach to health, emphasizing the importance of combining various therapies and maintaining an open mind.

    Covid-19 Study and Meditation

    Dr. Patel explains the study on meditation-induced factors as an adjuvant treatment for COVID-19, which was conducted using pseudo viruses to simulate the SARS-CoV-2 virus.

    He describes the survey data showing that avid meditators had less severe COVID-19 symptoms and faster recovery times.

    Dr. Patel details the laboratory experiments showing that plasma from meditators inhibited the virus from entering cells, suggesting a protective effect.

    He identifies serpin A5 as a key protein elevated in meditators, which may contribute to this protective effect.

    Twin Study and Socialization Dynamics

    Dr. Patel discusses the twin study, which explored the socialization and connectedness of identical and fraternal twins during a week-long meditation retreat.

    He describes the methodology, including separating twins at specific times during the retreat to measure their individual and collective changes.

    Dr. Patel highlights the significant biological divergence observed in twins during the retreat, followed by a convergence at the end.

    He speculates on the potential for socialization and connectedness to influence biological changes, beyond genetic factors.

    Future Research and Conclusion

    Dr. Patel mentions ongoing studies on the effects of meditation on aging, involving pairs of individuals with a 30-year age difference.

    He discusses the potential for meditation to improve healthy aging and the importance of multi-generational interactions.

    Dr. Patel touches on the concept of distant healing, where groups focus on individuals remotely, and the preliminary data showing significant biological changes.

    He concludes by emphasizing the need for further research to validate these findings and explore the mechanisms behind meditation's health benefits.

    _________________________________________________________________________

Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

Share

_________________________________________________________________________

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Nutrition, Prevention and Integrative Medicine Research for August 11, 2025

Nutrition, Prevention and Integrative Medicine…

AGING - FLAVONOL RICH FOODS - Associations between flavonoid-rich food and flavonoid intakes and incident unhealthy aging outcomes in older United States males and females. 10 Top Foods High in Flavonols (WebMed). Lettuce, Tomatoes, Onions, Kale, Apples, Grapes, Berries, Tea, Red wine.

AGING- SITTING - How Floor Sitting Can Improve Balance, Posture, and Longevity Americans often overlook floor sitting as an option that is associated with better joint mobility and balance that can reduce fall risk. By Amy Denney, EPOCH Times, 8/2/2025.
1) A systematic review of research on sitting and working furniture ergonomic from 2012 to 2022: Analysis of assessment approaches.
2) Postural and spinal stability analysis for different floor sitting styles.
3) The Biomechanical Effects of Cross-Legged Sitting on the Lower Limbs and the Implications in Rehabilitation.

BRAIN INJURY - CREATININE - Research Shows That Creatine May Protect The Brain From Injuries, By Molly Knudsen, M.S., RDN, MindBodyGreen, August 06, 2025.
1) Potential for use of creatine supplementation following mild traumatic brain injury.
2) Creatine supplementation enhances immunological function of neutrophils by increasing cellular adenosine triphosphate.
3) Creatine in Health and Disease.
4) Pilot study protocol of a randomized controlled trial for the potential effects of creatine monohydrate on persistent post-concussive symptoms.
5) Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials.
6) Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation.

COGNITION - ARTIFICIAL INTELLIGENCE (AI) - Every prompt may be coming at the cost of cognitive efficiency and creativity. By Makai Allbert, EPOCH Times, 7/30/2025.
1) Your Brain on ChatGPT: Accumulation of Cognitive Debt when Using an
AI Assistant for Essay Writing Task.
2) Habitual use of GPS negatively impacts spatial memory during self-guided navigation.

COGNITION - SUGAR - How Your Brain’s Sugar Processing Could Influence Alzheimer’s Disease Risk. A recent study links poor sugar processing in the brain to memory loss–but fasting and certain treatments may offer protection. By George Citroner, EPOCH Times, 8/7/2025.
1) Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reduction.

DEPRESSION - SSRIS- SEROTINON REUPTAKE INHIBITORS - The Dark Side of SSRIs. The shocking truth about SSRIs: minimal efficacy, serious withdrawal, and a debunked serotonin theory. Author Laura Delano joins Dr. Varon and Dr. Marik to discuss her book "Unshrunk". Unshrunk: A Story of Psychiatric Treatment Resistance Hardcover. March 8, 2025. by Laura Delano (Author). Independent Medical Alliance, Aug 08, 2025.

PARKINSON’S DISEASE - IVERMECTIN and FENBENDAZOLE Testimonial - 78 year old Nebraska PARKINSON'S DISEASE patient of 8 years, cured after 4 months!Dr. William Makis MD, Covid Intel, Aug 07, 2025.

SUDDEN DEATH - HEART ATTACK - HALF MARATHON - 28 year old Rugby player collapsed and died during the Great Bristol Run Half Marathon on May 12, 2025. Dr. William Makis MD, Covid Intel, Jul 16, 2025.

SUDDEN DEATH - MYOCARDITIS - INFLUENZA VACCINE - Childhood Vaccine Injuries - 7 year old Kaylynne Matten died after Influenza Vaccine. Dr. William Makis MD, Covid Intel, Jul 17, 2025.

VACCINES - COVID 19 - RESPIRATORY INFECTIONS - HHS to Terminate 22 BARDA mRNA Shot Projects Worth $500M. FK JR: "The data show these vaccines fail to protect effectively against upper respiratory infections like COVID and flu." Focal Points/ Courageous Discourse, Nicolas Hulscher, MPH, Aug 05, 2025.

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Cancer…

BIOPSIES - CANCER SPREAD - Doctor Who Cured 92% Of Cancer Patients Says Biopsies Are SPREADING Cancer. A needle biopsy punctures the tumor and releases the toxins into the system. Died Suddenly News, Aug 09, 2025. Doctor Who Has Saved Thousands of Lives Says Tumors are Protective Mechanisms but Biopsies Release Cancer Cells and Kill You.
1) Needle track seeding in renal mass biopsies.

CANCER - STATISTICS - INCIDENCE - Annual Report to the Nation 2025: Overall Cancer Statistics. Registry Data Show Mixed Picture. Peter A. McCullough, MD, MPH, Focal Points/ Courageous Discourse, Aug 09, 2025.
1) Seers.cancer.gov

CHEMOTHERAPY - CANCER CELLS - Chemotherapy awakens dormant cancer cells in lung by inducing neutrophil extracellular traps. “…This study provides direct evidence of dormancy awakening and reveals a mechanism underlying detrimental effect of chemotherapy on metastasis, highlighting potential strategies to improve cancer treatment…”

GASTRIC CANCER - IVERMECTIN and MEBENDAZOLE Testimonial - 72 year old Dallas, Texas woman with Stage 4 Gastric Cancer outlives her Oncologist's life expectancy prediction. Dr. William Makis MD, Covid Intel, Aug 05, 2025.

OVARIAN CANCER - IVERMECTIN and MEBENDAZOLE Testimonial - 76 year old San Francisco woman with Stage 4 Mullerian Carcinoma (Ovarian) with brain metastases reports after 3 months. Dr. William Makis MD, Covid Intel, Aug 09, 2025.

SARCOMA - IVERMECTIN and MEBENDAZOLE Testimonial - 25 year old woman in Greece with Stage 4 Ewing Sarcoma metastatic to the lungs, sees positive results after 2 months. Dr. William Makis MD, Covid Intel, Aug 05, 2025.

Covid Syndrome…

COVID VACCINE - MORE COVID INFECTION - Eighth Study Confirms mRNA Shots Increase Infection Risk. New study of 1,745 healthcare workers finds mRNA boosters raise risk of influenza-like illness by up to 70% and increase workdays lost by 50%. Nicolas Hulscher, MPH, Focal Point/Courageous Discourse, Aug 10, 2025.
1) Association of SARS-CoV-2 vaccination status with risk of influenza-like illness and loss of workdays in healthcare workers.
2) Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine.
3) Protection From COVID-19 Vaccination and Prior SARS-CoV-2 Infection Among Children Aged 6 Months–4 Years, United States, September 2022–April 2023.
4) Post-vaccination IgG4 and IgG2 class switch associates with increased risk of SARS-CoV-2 infections.
5) Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up: A Target Trial Emulation.
6) Behavioral and Health Outcomes of mRNA COVID-19 Vaccination: A Case-Control Study in Japanese Small and Medium-Sized Enterprises.
7) Rate of SARS-CoV-2 Reinfection During an Omicron Wave in Iceland.
8) Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar.
9) Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine.

COVID VACCINE - PUBLISHED STUDIES - The McCullough Foundation Has Published Over 20 Manuscripts Exposing the Dangers of COVID-19 mRNA Vaccination.Epidemiologist Nicholas Hulscher joins FNL Freedom News to discuss the McCullough Foundation’s vital research efforts — exposing mRNA harms and advancing solutions for the injured. Nicolas Hulscher, MPH, Focal Point/Courageous Discourse, Jul 16, 2025.

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Societal and World Health…

ENVIRONMENT - FOSSIL FUEL - Berkeley Professor Reveals That Drilling Oil in California Might Be Good for the Environment | James Rector, California Insider Show.

TRANSPLANT MEDICINE - ORGAN DONOR ABUSE - RFK Exposes 103 Cases of Organ Transplant Abuse. (YouTube) Prime Time, Epoch Times, Roman Balmakov,August 8, 20025.

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Don’t Spend Your Money…Go For a Walk….Powering Your Mitochondria with Red Light Therapy…An Interview with Professor Glen Jeffery

Glen Jeffery, PhD, BSc
Professor of Neuroscience
Institute of Ophthalmology, University College London
11-43 Bath St, London EC1V9EL, UK
g.jeffery@ucl.ac.uk (08-07-25 )
video interview click here

“Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision. Sci Rep 15, 24435 (2025) Full Article & Abstract

[Below is a ChatGPT summary of the unedited transcript from the video above with the article abstract with ChatGPT instructed to summarize and improve the grammar of the interview. This abbreviated summary was approved by Dr. Glen Jeffery and Kirk Hamilton PAC]

Improved Vision, Mitochondrial Function, and the Potential Benefits of Long-Wavelength Red Light Therapy

An Interview with Professor Glen Jeffery, PhD, BSc
Professor of Neuroscience, Institute of Ophthalmology, University College London

Interviewed by Kirk Hamilton, PAC
Host, Staying Healthy Today Show
Recorded: August 7, 2025

KIRK HAMILTON:
Hi everyone, I’m Kirk Hamilton, your host of the Staying Healthy Today Show—where we explore the fields of nutrition, prevention, and integrative lifestyle medicine. Today, we're diving into a fascinating topic: how longer wavelengths of light, specifically red and infrared, can improve vision and mitochondrial function.

When I saw the title of Professor Glen Jeffery’s recent study, “Longer Wavelengths in Sunlight Pass Through the Human Body and Have a Systemic Impact Which Improves Vision,” I was immediately intrigued. As someone who loves sunlight and believes it's benefits are more than just vitamin D I was very interested in talking to him.

So, joining us from London is Professor Glen Jeffery, PhD, Professor of Neuroscience at the Institute of Ophthalmology at University College London. Dr. Jeffery, thank you so much for being here today.

GLEN JEFFERY:
Thank you, it’s a pleasure.

Why This Research?

KIRK HAMILTON:
Let’s start at the beginning. What inspired you to study red and infrared light, and what were you hoping to discover?

GLEN JEFFERY:
Great question. About 15 years ago, I started seeing consistent evidence in the scientific literature showing that long-wavelength light—particularly in the red and near-infrared spectrum—has beneficial effects on cellular metabolism, particularly in mitochondria.

I also wanted to translate our lab findings into real-world scenarios, which is often a missing step in science. So, we did something simple: we exposed people to sunlight and measured what wavelengths actually passed through their bodies. We found that infrared light from the sun does penetrate through the torso, and we measured it coming out the back. That surprised us—but physicists had predicted it.

Then, we recreated that sunlight exposure in the lab using specific LED wavelengths (830–860 nm) and tested how that affected vision and mitochondrial function. The results were consistent: infrared light exposure improved vision, even when the eyes themselves weren’t directly exposed.

How Light Affects Mitochondria—and Vision

KIRK HAMILTON:
So how exactly does this type of light improve vision and mitochondrial function?

GLEN JEFFERY:
Well, mitochondria are the energy factories of your cells. When you hit them with long-wavelength light, they produce more ATP, the energy currency of the cell. That supports improved cellular function across the board.

Now, the retina has more mitochondria per cell than almost any other tissue, so it’s an ideal place to see an effect. We used a simple visual test—colored letters on a noisy background—to measure color contrast sensitivity. It’s an easy metric, and we saw improvements within 24 hours of exposure.

Sunlight vs Red Light Therapy Devices

KIRK HAMILTON:
Was the light in your studies natural sunlight, or did you use red light therapy devices?

GLEN JEFFERY:
Both. Sunlight has enormous amounts of infrared light—more than any LED device can reproduce. In the study, we first tested people outside and measured which wavelengths passed through their bodies. Then we created a lab device mimicking those wavelengths and got the same positive results indoors.

Clothing doesn’t block the infrared light, by the way—it attenuates it slightly but still lets it through. So whether you're wearing a shirt or not, sunlight’s longer wavelengths can still reach your tissues.

Practical Applications: Just Go for a Walk

KIRK HAMILTON:
So, for the average person—is just getting outside for a walk is enough?

GLEN JEFFERY:
Absolutely! Keep your credit card in your pocket and go for a walk. You’ll get all the infrared light you need—free of charge—and it’s incredibly beneficial.

Even on cloudy days, there’s still plenty of scattered infrared light. Water in the clouds does scatter it, but it doesn’t eliminate it. There’s no excuse not to go outside.

Critical Care, Architecture, and Incandescent Bulbs

KIRK HAMILTON:
So how does this research apply in places like hospitals or care homes?

GLEN JEFFERY:
Hospitals and modern buildings are a problem. Most indoor lighting is LED-based, which contains zero long-wavelength infrared light. That’s why we’ve been working with critical care units in major London hospitals to introduce light sources that enrich the environment with infrared.

One of the best solutions? Old-fashioned incandescent bulbs. They produce a smooth spectrum of light, very similar to sunlight, including plenty of infrared. They’re cheap, effective, and much better than most “full-spectrum” LEDs.

Unfortunately, they're being phased out in both the US and UK for energy efficiency reasons. But from a health perspective—especially for mitochondrial function—incandescents are far superior.

Real-World Impacts: Grip Strength, Vision, Inflammation

KIRK HAMILTON:
Have you seen other measurable benefits besides vision?

GLEN JEFFERY:
Yes, other researchers in London have shown that grip strength improves with similar light exposure. That’s a big deal for aging populations. Better grip strength means improved motor function, fewer falls, and longer healthspan.

There’s also a fantastic study from a U.S. city where they planted thousands of trees and found that residents' CRP levels—an inflammation marker—went down. Trees reflect infrared light. So, just walking through greenery can shower you in therapeutic infrared.

On Aging, Vision, and Public Health

KIRK HAMILTON:
You mentioned earlier vision and aging. Can regular exposure to this light help prevent vision loss, like macular degeneration?

GLEN JEFFERY:
Yes, we’ve shown that older individuals experience improved color vision after red light exposure. I did a clinical trial for macular degeneration that didn’t succeed—likely due to patient selection—but another UK trial just finished and showed significant benefits in early-stage macular degeneration.

This kind of light could become a non-invasive therapy for age-related conditions where mitochondrial decline plays a central role.

Final Thoughts: Simple, Free, and Effective!

KIRK HAMILTON:
This has been incredibly eye-opening. Any final thoughts you'd like to share?

GLEN JEFFERY:
Sure. Let me say it again: Don’t spend your money. Just go for a walk. The cardiovascular benefits of walking are well known, but now we know it also recharges your cellular batteries—your mitochondria.

And to be clear, I have half a dozen expensive red light devices sitting in my office—sent to me by companies. Some of them have $15 worth of parts and sell for thousands. The science doesn’t require that. Just step outside.

KIRK HAMILTON:
That’s a great way to end. Go for a walk, recharge your mitochondria, and save your money. Thank you, Dr. Jeffery, for your time, your research, and for bringing this down to earth.

GLEN JEFFERY:
My pleasure, Kirk. Stay well.

Key Takeaways:

  • Infrared light (830–860 nm) from sunlight penetrates deeply through the body and boosts mitochondrial function.

  • This improves vision, grip strength, motor skills, and likely reduces inflammation.

  • Sunlight is more effective than most red light therapy devices—and it's free.

  • Even clothing doesn’t block therapeutic infrared light.

  • Modern lighting—especially LED—removes infrared, potentially impacting long-term health.

  • Incandescent bulbs offer a more natural light spectrum and may support better health indoors.

    Kirk’s Comments:

  • Dr. Jeffery and colleagues work confirms my own personal experience that feeling better in sunlight goes beyond vitamin D but could be the energy and well-being enhancement of improved mitochondrial function and ATP production (and vitamin D!).

  • How convenient that you can get a beneficial ATP boosting effect even with your clothes on and even on an overcast day and you are walking through trees! All you have to do is go outside and walk!

  • The designing of the new Mayo Clinic building on the east coast that will be mostly glass, and Dr. Jeffery’s discussion about patients being close to windows in the critical care units dong better, reminds me after my colon cancer surgery (colectomy). As I was walking in the hospital hallways and I would sit with my back up against the window and feel the warm of the sun coming through the window and how good that felt! Stimulating mitochondria I bet!

  • I think of how many conditions and patients could improve just by walking or exercising outside!

  • It was very intriguing that grip strength improved by those getting longer wavelengths of light.

  • And for those that have macular degeneration get out side and get exposed to full spectrum light.

  • It left with me a smile on my face with incandescent lights being potentially healing and how we have tried to do away with them. If I can I am going to get a few lamps with incandescent lights for my home.

  • When in doubt. Keep your wallet in your pocket and go for a walk even on a cloudy day or under trees. You will still get some benefit from full spectrum long wavelength healing light. Your ATP producing mitochondria with thank you…And you might also prevent a fall with improved grip strength.

FOR THIS ENTIRE “STAYING HEALTHY TODAY” POST CLICK HERE

FOR KIRK HAMILTON’S SUBSTACK “STAYING HEALTHY TODAY CLICK HERE

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
StayingHealthyToday Substack
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Research in Nutrition, Prevention and Integrative Medicine August 2, 2025

Nutrition, Prevention and Integrative Medicine…

AGING - DIET - BEANS - LEGUMES -5 Delicious Ways to Eat a Cup of Beans Each Day By Tim Cebula, Blue Zones News Letter, July 2025.
1) Savory Roasted Chickpeas
2) Sardinian Pasta Fagioli
3) One-Hour, Crowd-Feeding Chili
4) Red Beans And Rice
5) Lentil Gnocchi
6) Ikarian Longevity Stew With Black Eyed Peas
7) Okinawan Rice and Bean Sprouts
8) Black Bean Breakfast Burritos
9) Panchita’s Gallo Pinto
10)Miso Soup with Vegetables
11) Black Bean Chocolate Chunk Brownies
12) Bush Beans - Blue Zones

AGING - DIET - CARBOHYDRATES - WOMEN - The Truth About Carbs For Women’s Health, According To Science, By Ava Durgin, , MindBodyGreen, July 28, 2025.
1) Dietary Carbohydrate Intake, Carbohydrate Quality, and Healthy Aging in Women.

AGING - PRESCHOOL - INTERGENERATIONAL PROGRAMS - What Happens When You Integrate a Preschool into a Long-Term Care Facility? Joy and Purpose for All. By Aislinn Kotifani, Blue Zones Newsletter, 2025.
1) Multigenerational Living Is the New Rapidly Growing Trend.
2) Intergenerational programs: What can school-age children and older people expect from them? A systematic review.
3) MAKING THE CASE FOR INTERGENERATIONAL PROGRAMS.
4) Intergenerational Day Centers: A New Wave in Adult and Child.

ALZHEIMER’S DISEASE - EGG - Association of Egg Intake With Alzheimer’s Dementia Risk in Older Adults: The Rush Memory and Aging Project. (“…These findings suggest that frequent egg consumption is associated with a lower risk of Alzheimer’s dementia and AD pathology, and the association with Alzheimer’s dementia is partially mediated through dietary choline…”). Kirk’s Comment: Eggs are one of the more frequent allergens/food intolerances while on paper good nutritionally. If you eat them daily or 3-4 times per week take two weeks off and see if any annoying symptoms go away or come back upon reintroduction. Eggs also have been associated with Type 2 diabetes. Make sure you are trim and have an hemoglobin A1C 5.6 or less if you are an egg eater.

BLOOD PRESSURE - BEET JUICE - Ageing modifies the oral microbiome, nitric oxide bioavailability and vascular responses to dietary nitrate supplementation. “…Greater blood pressure benefits from supplemental dietary nitrate in older compared to younger people are mediated primarily by the suppression of potentially harmful oral bacteria, that have been associated with ammonia production…”

BRAIN VOLUME - MAGNESIUM - Dietary magnesium intake is related to larger brain volumes and lowerwhite matter lesions with notable sex differences.

CARDIOVASCULAR DISEASE - COCOA FLAVONOL - Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.

CARDIOVASCULAR EVENT - Systematic Review Finds Devastating Cardiopulmonary Adverse Events after COVID-19 Vaccination. Thousands of Papers Identified Heart and Lung Damage, Biased AI Falsely Claims "Rare and Mild". Peter A. McCullough, MD, MPH, Focal Point/Courageous Discourse, Jul 29, 2025.

COGNITIVE FUNCTION - CARDIOVASCULAR DISEASE - Wild blueberry (poly)phenols can improve vascular function and cognitive performance in healthy older individuals: a double-blind randomized controlled trial.

COGNITION - SLEEP - This One Sleep Habit Might Matter More Than Hours Slept For Cognitive Health, By Ava Durgin, MindBodyGreen, July 25, 2025.
1)Lower slow wave sleep and rapid eye movement sleep are associated with brain atrophy of Alzheimer’s disease-vulnerable regions.
2) β-Amyloid accumulation in the human brain after one night of sleep deprivation.
3) The Dynamic Relationship between the Glymphatic System, Aging, Memory, and Sleep.
4) The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.
5)Exercise improves the quality of slow-wave sleep by increasing slow-wave stability.
6) The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysis.

COLORECTAL CANCER - VITAMIN D - Vitamin D’s Potential Role in Colorectal Cancer Prevention, Immune Health.

COLORECTAL CANCER - VITAMIN D - Vitamin D and Colorectal Cancer Prevention: Immunological. “…Maintaining optimal vitamin D levels and adequate dietary intake is crucial in preventing CRC and improving patient prognosis…”

DEMENTIA - IVERMECTIN Testimonial in Dementia - 92 year old mother in Japan has incredible response to low dose Ivermectin in her last months. Dr. William Makis MD, Covid Intel, Aug 01, 2025.

DEPRESSION - MAGNESIUM - Magnesium Depletion Linked to Depression and How to Replenish It Effectively. Personalized nutrition strategies offer new hope for low magnesium and mood disorders. By Zena le Roux, EPOCH Times, 7/28/2025.
1) Magnesium depletion score and depression: a positive correlation among US adults.
2) Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose–Response Meta-analysis of Epidemiologic Studies.

DIABETES RISK - SUGAR - 'Drinking your sugar is more problematic for health than eating it'
1) Dietary Sugar Intake and Incident Type 2 Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

DIABETES RISK - VITAMIN D - Vitamin D Helps Balance Blood Sugar & Reduce Type 2 Diabetes Risk. By Morgan Chamberlain, MindBodyGreen, July 21, 2025.
1) Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China.
2) Vitamin D and type 2 diabetes. (Dr. Paul Lips, Department of Internal Medicine, Endocrine Section, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. p.lips@vumc.nl )

ENVIRONMENT - GREENHOUSE GASES - CARBON DIOXIDE -Physics Demonstrates That Increasing Greenhouse Gases Cannot Cause Dangerous Warming, Extreme Weather Or Any Harm. More Carbon Dioxide Will Create More Food. Driving Greenhouse Gas Emissions to Net Zero and Eliminating Fossil Fuels Will Be Disastrous for People Worldwide. SUMMARY FULL PAPER by
1) Richard Lindzen, PhD, Professor of Earth, Atmospheric, and Planetary Sciences, Emeritus, Massachusetts Institute of Technology
2) William Happer, PhD, Professor of Physics, Emeritus, Princeton University

FIBROMYALGIA - DIET - SUPPLEMENTS - STRESS - SLEEP - EXERCISE - ALTERNATIVE THERAPIES - Fibromyalgia: A Chronic Condition With Widespread Pain—Natural Ways to Relieve It. Fibromyalgia affects how the body processes pain, leading to a range of symptoms. By Mercura Wang, EPOCH Times, July 22, 2025.

INFECTIOUS DISEASE - POST COVID PANDEMIC - Pandemic Aftermath: Why Infectious Diseases Are Surging—And How I’d Treat Myself If I Fell ILL. Here, I do a deep dive into the"mysterious" rise of infectious diseases worldwide—and my straightforward, practical approach to treating infectious illnesses if they were to strike me or my family. Pierre Kory, MD, MPA, Pierre Kory’s Medical Musings Jul 28, 2025.

LIVER DISEASE - CANCER - Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Liver Cancer and Chronic Liver Disease Mortality. “…Findings: In 98 786 postmenopausal women followed up for a median of 20.9 years, compared with consuming 3 servings or less of sugar-sweetened beverages per month, women consuming 1 or more servings per day had significantly higher rates of liver cancer (18.0 vs 10.3 per 100 000 person-years; adjusted hazard ratio [HR], 1.85) and chronic liver disease mortality (17.7 vs 7.1 per 100 000 person-years; adjusted HR, 1.68)…” (Author: Xuehong Zhang, MBBS, ScD, Brigham and Women’s Hospital and Harvard Medical School, 181 Longwood Ave, Room 453, Boston, MA 02115 (xuehong.zhang@channing.harvard.edu).

MITOCHONDRIAL FUNCTION - VISION - SUNLIGHT - NEW STUDY: Sunlight Penetrates the Human Body, Improving Mitochondrial Function and Vision. Just 15 minutes of fully clothed infrared sunlight exposure triggered systemic effects and measurable improvements in vision — even with eyes completely covered. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Jul 14, 2025.
1) Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision.

MITOCHONDRIAL DYSFUNCTION - SSRIs - SSRIs Can Cause Severe Mitochondrial Dysfunction. Installment eight in our series on understanding the truth about SSRIs. Chris Masterjohn, PhD, Harnessing the Power of Nutrients, Jul 29, 2025.

STROKE - HEMORRHAGIC - mRNA Injury Stories - 17 year old VOICE Star Karen Silva dies of hemorrhagic stroke. Dr. William Makis MD, Covid Intel, Aug 01, 2025.

SUDDEN DEATH - UNEXPLAINED - DOCTOR - mRNA Injury Stories - 30 year old Dr.Meliah Blair (Veterinarian) of Newport KY, died unexpectedly at her home on May 11, 2025. Dr. William Makis MD, Covid Intel, Jul 15, 2025.

THYROID FUNCTION - NUTRIENTS - IODINE- SELENIUM- IRON- ZINC- COPPER- MAGNESIUM - VITAMIN A - VITAMIN B12
1) The Role of Nutrition on Thyroid Function

TOXICITY - GLYPHOSATE - CHINA - Why Are We Paying China to Poison Us? And why did Congress just make it harder to fight back? Mollie Engelhart, EPOCH Times, 7/26/2025.

VACCINATION - EFFICACY - AMERICAN ACADEMY OF PEDIATRICS - American Academy of Pediatrics tacitly admits that vaccines don't work! If vaccines worked, vaccinated kids would have NOTHING to fear from unvaccinated kids. So why do we need to protect them? Steve Kirsch, Steve Kirsch's newsletter,
Jul 28, 2025.

Cancer…

BLADDER CANCER - COVID VACCINE - BLOOD CLOTS - After COVID-19 Vaccine Blood Clots, Deion Sanders Hit with Turbo Cancer. Unusual Aggressive Bladder Cancer Reported During Pandemic in Literature. Peter A. McCullough, MD, MPH, Focal Points/Courageous Discourse, Jul 31, 2025.

BLADDER CANCER - COVID-19 VACCINATION - Vaccination and Bladder Cancer Deion Sanders Vaccine Turbo Cancer Brings Issue to Light. Peter A. McCullough, MD, MPH, Aug 02, 2025.

BLADDER CANCER - IVERMECTIN - FENBENDAZOLE - High-Grade Non-Invasive Bladder Cancer, age 69, Male. Surgery, Ivermectin and Fenbendazole. Ben Fen, Jul 27, 2025.
1) Fenbendazole as an Anticancer Agent? A Case Series of Self-Administration in Three Patients.

CANCER RISK - EXERCISE - This Simple Well-Researched Habit Cuts Cancer Death Risk By Nearly 50%. By Ava Durgin, MindBodyGreen, March 10, 2025. “…Could just 60 minutes of moderate exercise per week significantly improve cancer outcomes? According to a study published in the British Journal of Sports Medicine, the answer is a resounding yes?…”
1) Association between recorded physical activity and cancer progression or mortality in individuals diagnosed with cancer in South Africa.

PANCREATIC CANCER - IVERMECTIN and FENBENDAZOLE - 69 year old New York man with Stage 4 Pancreatic Cancer and CA19-9 14934 reports after 2 months. Dr. William Makis MD, Covid Intel, Jul 31, 2025.

PROSTATE CANCER - FENBENDAZOLE - Case Report: Metastatic Prostate Cancer, Liver and Lymph Node Metastases, age 74. Metastatic Stage IV Prostate Cancer Squashed with Fenbendazole. Ben Fen, Jul 29, 2025.

Covid Syndrome…

COVID VACCINATION - BOOSTER - IMMUNE SYSTEM - INFLAMMATION - COAGULATION - mRNA Boosters Trigger Dangerous Immune & Blood Abnormalities Within 48 Hours in Healthy Young Adults. Even without symptoms, mRNA boosters trigger immune suppression, systemic inflammation, and coagulation abnormalities. Nicolas Hulscher, MPH, Focal Point, Courageous Discourse, Jul 28, 2025.
1) Immune and hematologicak responses to the third dose of an mRNA COVID-19 vaccine: a six-month longitudinal study. “…Conclusions: A booster dose with an mRNA vaccine at the recommended time causes the anti-SARS-CoV-2 IgG and IgA levels to increase rapidly and for at least six months. The increase in inflammatory cytokines and changes in the coagulation profile are consistent with the vaccine’s normal immune induction mechanism. Mild AEFIs (adverse events following immunization) were reported in a minority of vaccine recipients. The consistent subclinical changes in inflammatory and coagulation markers suggest that these pathways may be involved in the pathogenesis of severe ARFIs reported with mRNA vaccines…”

COVID VACCINATION - GENETIC DISRUPTION - CANCER- CHRONIC DISEASE - BREAKING STUDY: mRNA Injections Induce Severe, Long-Lasting Genetic Disruption Linked to Cancer and Chronic Disease. Landmark study reveals COVID-19 “vaccines” severely disrupt the expression of thousands of genes—triggering mitochondrial failure, immune reprogramming, and oncogenic activation. Nicolas Hulscher, MPH, Focal Points/Courageous Discourse, Jul 25, 2025.
1) Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination. “…Conclusions: The observed transcriptomic profiles indicate persistent cellular stress responses, mitochondrial dysfunction, and immune dysregulation following exposure to mRNA vaccines, potentially in susceptible individuals. Shared and distinct molecular signatures in both cohorts demonstrate underlying mechanisms contributing to post-vaccine symptomatology and complications, including oncogenesis and or progression of malignant disease. These findings underscore the need for a deeper investigation into the long-term safety of mRNA vaccines and host response variability…”

COVID VACCINATION - HAIR LOSS - COVID-19 Vaccination — Not Infection — Increases Risk of Multiple Hair Loss Disorders. Massive study of 5.7 million Koreans finds COVID-19 vaccination significantly increases the risk of complete hair loss, patchy autoimmune hair loss, and excessive shedding. Nicolas Hulscher, MPH, Focal Points/Courageous Discourse, Jul 31, 2025.
1) New Onset of Hair Loss Disorders During the Coronavirus Disease 2019 Pandemic: A Korean Nationwide Population-Based Study. “…Conclusion: COVID-19 vaccination was positively correlated with hair loss disorders but not COVID-19 infection…”

COVID VACCINATION - MYOCARDITIS - MRI - Cardiac MRI One Year after COVID-19 Vaccination Valuable in Detecting Heart Damage. Sustained Myocarditis Concerning in Young Persons. Peter A. McCullough, MD, MPH, Focal Points/Courageous Discourse, Jul 27, 2025.
1) Resolution of Refractory COVID-19 Vaccine-Induced Myopericarditis with Adjunctive Rapamycin.
2) Improved diagnosis of COVID-19 vaccine-associated myocarditis with cardiac scarring identified by cardiac magnetic resonance imaging.

COVID VACCINATION -MYOCARDITIS - CARDIAC MRI - Improved diagnosis of COVID-19 vaccine-associated myocarditis with cardiac scarring identified by cardiac magnetic resonance imaging. (Professor Andrew J Taylor, Department of Cardiology, Alfred Hospital, Melbourne, Victoria, Australia / Department of Cardiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia. andrew.taylor2@mh.org.au “…Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) occurred in one-third of patients with COVID-19 vaccine-associated myocarditis (C-VAM). Without CMR at the time of diagnosis, almost one-third of patients are misclassified as probable rather than definite myocarditis, indicating a diagnostic strategy using echocardiography alone is insufficient…”

COVID VACCINATION - SPIKE PROTEIN - NATTOKINASE - Spanish "Vaxtherapy" Positions Nattokinase First Line. Handling Spike Protein as Core Culprit is Primary Goal in Treating Long-Vax Syndromes. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Jul 30, 2025.
1) Vaxtherapy, a Multiphase Therapeutic Protocol Approach for Longvax, the COVID-19 Vaccine-Induced Disease: Spike Persistence as the Core Culprit and Its Downstream Effects.

COVID VACCINATION - IMMUNE FUNCTION - INFLAMMATION- COAGULATION - mRNA Boosters Trigger Dangerous Immune & Blood Abnormalities Within 48 Hours in Healthy Young Adults. Even without symptoms, mRNA boosters trigger immune suppression, systemic inflammation, and coagulation abnormalities. Nicolas Hulscher, MPH, Focal Points, Courageous Discourse, Jul 28, 2025.
1) Immune and hematologicak responses to the third dose of an mRNA COVID-19 vaccine: a six-month longitudinal study.

POST COVID SYNDROME - BRAIN FOG - COGNITION - This SARS-spike thing they made ruins brains. A new study demonstrates hypometabolism (reduced glucose uptake) in specific areas of the human brain - think reason for brain fog. Jessica Rose, Unacceptable Jessica, Jul 15, 2025.
1) Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing. “…The results showed significant hypometabolism in the bilateral frontal, temporal, and parietal lobes, as well as in the left occipital lobe, along with predominantly frontal EEG slowing in post-COVID-19 patients compared to healthy controls…The observed PET hypometabolism and EEG slowing patterns in anterior brain regions, may help to elucidate the pathophysiological mechanisms underlying cognitive decline in post-COVID-19 patients…”

FOR THIS ENTIRE “STAYING HEALTHY TODAY” POST CLICK HERE

FOR KIRK HAMILTON’S SUBSTACK “STAYING HEALTHY TODAY CLICK HERE

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
StayingHealthyToday Substack
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Colon Cancer and Vitamin D, Mechanisms in Prevention and Treatment an Interview with Professors János Tamás Varga, MD and Mónika Fekete

Watch Kirk Hamilton PAC’s Video Summary of This Interview Here

Professor János Tamás Varga, MD
Department of Pulmonology, Semmelweis University
1083 Budapest, Hungary
varga.janos.tamas@semmelweis.hu

Mónika Fekete, MD
Institute of Preventive Medicine and Public Health
Faculty of Medicine, Semmelweis University
1089 Budapest, Hungary
fekete.monika@semmelweis.hu

“Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications,”
Nutrients. 2025 Apr 15;17(8):1351 (7/2025)

Kirk Hamilton: Can you please share with me your educational background and current position?

Dr. Mónika Fekete and Prof. János Tamás Varga: The authors of the study are affiliated with various faculties and research institutes of Semmelweis University, primarily working in preventive medicine, nutrition science, immunology, pulmonology, and cardiovascular medicine. Several authors hold medical degrees (MD) and PhDs, and currently serve as educators, researchers, or clinicians within different departments of Semmelweis University (e.g., Department of Preventive Medicine and Public Health, Heart and Vascular Clinic, Department of Rheumatology and Clinical Immunology, Department of Pulmonology). We also collaborate with the HUN-REN Energy Science Research Centre. The corresponding author of the article is Prof. János Varga, Professor at the Department of Pulmonology, Semmelweis University.

KH: What got you interested in studying the role of vitamin D in colorectal cancer prevention and treatment?

MF & JTV: Colorectal cancer (CRC) is one of the most common cancers and causes of cancer-related mortality worldwide. Therefore, research into preventive strategies is of high importance for public health and preventive medicine. The role of vitamin D has gained increasing attention not only for bone metabolism but also for its immunomodulatory and anti-inflammatory effects over the last decade.

Our research group was motivated by the observed epidemiological and clinical associations between vitamin D deficiency and CRC incidence. However, many underlying mechanisms remain unclear. We were particularly interested in exploring the immunological and inflammatory pathways involved, as they play key roles in carcinogenesis and could serve as targets for preventive strategies.

Furthermore, nutritional and lifestyle aspects of vitamin D — such as supplementation optimization and addressing population-wide deficiencies — are especially relevant for public health practice.

KH: What is the mechanism of how vitamin D adequacy may prevent colorectal cancer?

MF & JTV: Vitamin D, especially its active form calcitriol (1,25(OH)₂D₃), regulates multiple cellular processes critical in cancer prevention:

  • Cell differentiation and proliferation inhibition: Activation of the vitamin D receptor (VDR) promotes normal cell differentiation and inhibits excessive cell division, which is crucial in colorectal epithelial cells where dysregulated proliferation can lead to cancer.

  • Promotion of apoptosis: Calcitriol induces programmed cell death in damaged or transformed cells, eliminating potentially cancerous cells.

  • Modulation of inflammatory pathways: Vitamin D suppresses pro-inflammatory cytokines (e.g., IL-6, TNF-α) while promoting anti-inflammatory mediators (e.g., IL-10), which is important given the link between chronic inflammation (such as ulcerative colitis) and CRC risk.

  • Immunomodulation: Vitamin D balances innate and adaptive immunity, enhancing tumor-fighting cytotoxic T cells (CD8⁺) and reducing pro-tumor immune populations (e.g., Th17 cells).

  • Effects on the microbiome: Vitamin D influences gut microbiota composition, which is linked to CRC development by maintaining intestinal barrier function and immune homeostasis.

In summary, vitamin D acts as an active biological regulator through multiple cellular and immunological pathways, contributing to colorectal cancer prevention.

KH: What is the mechanism of how vitamin D may be beneficial as an adjunctive treatment of colon cancer?

MF & JTV: The active form of vitamin D supports CRC therapy through:

  • Antiproliferative effects by activating cell cycle inhibitors (p21, p27) that block tumor cell division.

  • Induction of apoptosis via activation of BAX/BAK pathways.

  • Inhibition of Wnt/β-catenin signaling, crucial in tumor development, and enhancement of E-cadherin and DKK-1 expression.

  • Immunomodulation and reduction of inflammation, including suppression of IL-6 and IL-8.

  • Antiangiogenic effects by decreasing HIF-1α and VEGF levels, inhibiting new blood vessel formation.

  • Potential improvement of chemotherapy response and reduction of recurrence risk, particularly with optimal serum vitamin D and micronutrient levels (e.g., magnesium).

Thus, vitamin D has complex cellular and immune effects that make it a promising adjuvant in personalized combined CRC treatment.

KH: What role does vitamin D adequacy play in the prevention of recurrence of colorectal cancer?

MF & JTV: Increasing evidence suggests adequate vitamin D levels are important not only in preventing CRC onset but also in reducing recurrence and progression. Calcitriol’s immunomodulatory, anti-inflammatory, cell cycle inhibitory, and pro-apoptotic effects may suppress residual tumor cells and prolong cancer-free survival.
Several clinical studies support this:

Although not all studies showed significant differences, overall data suggest vitamin D supplementation—especially achieving optimal serum levels—may reduce recurrence risk and improve survival, influenced by individual factors like BMI, magnesium intake, and baseline vitamin D status.

KH: What is a “preventive” blood level of vitamin D3?

MF & JTV: The preventive blood level refers to the optimal serum 25-hydroxyvitamin D concentration associated with reduced risk of CRC development and recurrence. Current literature generally accepts a minimum level of 30 ng/ml (75 nmol/L), above which protective effects increase.

Some studies suggest levels of 36–40 ng/ml (90–100 nmol/L) may offer even stronger protection. Levels below 30 ng/ml indicate insufficiency or deficiency, associated with higher cancer and chronic disease risk.

It is important to avoid excessively high levels (>100 ng/ml or 250 nmol/L), which pose health risks such as hypercalcemia.
In summary:

  • Minimum recommended: ≥ 30 ng/ml (75 nmol/L)

  • Optimal/preventive range: 36–40 ng/ml (90–100 nmol/L)

  • Potentially harmful level: > 100 ng/ml (250 nmol/L)

Individual needs and health status should guide supplementation, with medical supervision and regular monitoring.

KH: There is debate about the optimal serum level of vitamin D for cancer prevention, treatment and recurrence prevention. You leave a wide gap from ”Optimal” 36-40 ng/ml and ”Potentially harmful” > 100 ng/ml of 40-100 ng/ml? As a health practitioner who has done 1000s of vitamin D levels on patients I have never seen side effects under 100 ng/ml (unless they have parathyroid or kidney disease) and I see people taking 5000 IU routinely of vitamin D3 getting into the 30-50 ng/ml range. Personally for general health reasons and as someone who has had colon cancer I try and keep my vitamin D levels between 50-75 ng/ml. That takes about 10,000 IU per day 5-7 days per week. A 2000 IU/d dose for an adult seems to be low in my clinical experience to get levels even to 30 ng/ml? To me toxic side effects between 30-100 ng/ml are not an issue. What needs to be done is doses studied between 5000-10,000 IU per day to a get level between 50-100 ng/ml to see if there really is clinical benefit in colon cancer prevention, treatment and cancer recurrence.

1. Vitamin D Page 73 https://imahealth.org/wp-content/uploads/2023/06/Cancer-Care-FLCCC-Dr-Paul-Marik-v2.pdf

2. Vitamin D: Evidence-Based Health Benefits and Recommendations for Population Guidelines

You may have already addressed this in your answers above but do you have any additional comments on higher doses of vitamin D for prevention, adjunctive cancer treatment and prevention of cancer recurrence?

MF & JTV: Thank you for the thoughtful comments and clinical insights. We agree that the currently accepted optimal serum levels of vitamin D are indeed debated, particularly in oncology. While most population guidelines (including those from WHO and national authorities) define 30–50 ng/mL as a safe and physiologically sufficient range, some clinical observations — especially in cancer patients or those at high risk — suggest that higher levels (e.g., 50–75 ng/mL) might be beneficial.

However, it is important to note that vitamin D is a fat-soluble vitamin that accumulates in the body over time. Therefore, from a public health and safety standpoint, most national and international recommendations define 4000 IU/day as the tolerable upper intake level for healthy adults. Exceeding this level chronically may increase the risk of adverse events (e.g., nephrocalcinosis or hypercalcemia), especially in individuals with comorbidities or genetic susceptibilities.

In the SUNSHINE clinical trial — one of the most relevant interventional studies in metastatic colorectal cancer — patients received a bolus dose of 8000 IU/day only for the first 2 weeks, followed by 4000 IU/day as maintenance, confirming that even in oncology settings, long-term very high doses are typically avoided. PubMed link: https://pubmed.ncbi.nlm.nih.gov/30964527/

We fully acknowledge your clinical experience and agree that doses between 5000–10,000 IU/day may be necessary in certain cases (e.g., high BMI, limited sunlight exposure) to achieve higher serum levels. However, the long-term safety of sustained serum levels above 75–100 ng/mL still requires rigorous, randomized controlled trials, particularly in oncology.

Please note that we are not clinical oncologists, and in our article we approached the topic of vitamin D supplementation from a public health and preventive medicine perspective, not as a cancer treatment protocol. The SUNSHINE trial itself used only a short-term loading dose of 8000 IU/day followed by a maintenance dose of 4000 IU/day, which aligns with the globally recognized safe upper limit.

KH: What is a good blood level of vitamin D to achieve while someone is being treated for colon cancer?

MF & JTV: For CRC patients undergoing treatment, maintaining an optimal 25(OH)D level between 30–50 ng/ml (75–125 nmol/L) is advised. This range is associated with improved survival, reduced recurrence risk, and favorable effects on immune function and inflammation.
Evidence includes:

  • Epidemiological data linking serum 25(OH)D above 30 ng/ml to better prognosis and lower recurrence.

  • Hormonal effects of vitamin D that support anti-cancer mechanisms and enhance treatment efficacy.

  • Clinical practice recommends individualized supplementation with regular blood level monitoring, considering factors such as body weight, ethnicity, and ongoing therapies.

  • Avoiding toxic levels (>100 ng/ml) is crucial to prevent hypercalcemia.
    Monitoring and maintaining appropriate vitamin D status is part of comprehensive cancer care to improve quality of life and outcomes.

KH: Can you tell us about your study and the basic results?

MF & JTV: Our study, titled “Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications,” aimed to provide a comprehensive overview of vitamin D’s role in CRC prevention, focusing on immunological mechanisms, inflammatory pathways, and nutritional aspects.
We performed a literature review analyzing vitamin D’s various effects on CRC risk reduction. Key highlights include:

  • The active form, 1,25-dihydroxyvitamin D3, regulates tumor cell proliferation, promotes differentiation, and induces apoptosis, thereby inhibiting tumor growth.

  • Vitamin D modulates inflammatory signaling pathways (e.g., NF-κB, IL-6, TNF-α) critical in CRC pathogenesis.

  • Maintaining adequate vitamin D levels through sunlight exposure, diet, and supplementation is important for CRC prevention.

  • Epidemiological and clinical data collectively suggest that optimal 25(OH)D levels can reduce CRC incidence and improve survival.

  • We emphasize regular monitoring of vitamin D status, especially in high-risk populations.

Overall, our study supports that vitamin D plays a key role beyond bone health, acting through immune and inflammatory regulation to contribute to primary CRC prevention.

KH: Is there an advantage of vitamin D levels attained by being in the sun versus by vitamin D taken by mouth? Said differently, is there something from sun exposure that may additionally be beneficial for the prevention or treatment of colon cancer?

MF & JTV: Vitamin D levels can be raised both through skin synthesis triggered by sunlight exposure (UV-B radiation) and by oral vitamin D supplementation. However, vitamin D production via sunlight may have certain advantages. The synthesis of vitamin D3 in the skin is regulated by natural feedback mechanisms that limit excessive vitamin D formation, thereby reducing the risk of vitamin D toxicity. This regulation aligns with kidney-based control processes and represents the skin’s natural protective mechanism.

Moreover, UV radiation itself exerts multiple beneficial biological effects that may contribute to colorectal cancer prevention and treatment. Some studies have shown that sun exposure has positive immunomodulatory effects and promotes anti-inflammatory processes, which play important roles in slowing cancer progression. Vitamin D additionally induces apoptosis in certain cancer cell lines, including colorectal cancer cells, making the maintenance of adequate vitamin D levels crucial.

At the same time, sun exposure must be kept within safe limits to avoid the risk of skin cancer caused by excessive UV radiation. Proper photoprotection and avoiding sunburn maximize the benefits of sunlight-driven vitamin D synthesis. When UV exposure is limited—due to season, latitude, or other factors—oral vitamin D supplementation remains an effective and safe alternative.

In summary, vitamin D derived from sun exposure is advantageous not only due to its natural regulatory mechanisms but also because of the additional immune- and inflammation-modulating effects of UV radiation, which may contribute to colorectal cancer prevention and treatment. Achieving optimal effects requires both safe sun exposure practices and medically supervised vitamin D supplementation.

KH: How important is vitamin D as a single nutrient/hormone in the prevention, treatment, and prevention of recurrence of colon cancer?

MF & JTV: Vitamin D plays a significant role as a single nutrient and hormone in the prevention, treatment, and prevention of recurrence of colorectal cancer. Numerous epidemiological and clinical studies have demonstrated that maintaining adequate serum 25(OH)D levels—generally above 30 ng/mL (75 nmol/L)—is associated with a reduced risk of colorectal cancer and improved survival outcomes in patients.

Mechanistically, the active form of vitamin D, calcitriol (1,25-dihydroxyvitamin D3), exerts multiple cellular effects that directly influence tumor progression. It promotes apoptosis of cancer cells, inhibits proliferation, reduces inflammation, and supports the effective functioning of the immune system. These actions are key not only in preventing tumor development but also in treating existing tumors and decreasing the risk of disease recurrence.

However, it is important to note that colorectal cancer is a complex disease influenced by numerous genetic, environmental, and lifestyle factors. Therefore, vitamin D should not be regarded as a standalone “miracle cure” but rather as part of a comprehensive preventive and therapeutic strategy that includes appropriate lifestyle, nutrition, and medical treatment.

In summary, vitamin D is a key nutrient and hormone in colorectal cancer prevention, treatment, and recurrence prevention, but its effectiveness is best realized within a multidisciplinary approach.

KH: Do you have any further comments on this interesting topic?

MF & JTV: Raising serum 25-hydroxyvitamin D levels above 30 ng/mL (75 nmol/L) can significantly contribute—based on many epidemiological and clinical studies—to reducing the risk of chronic diseases, including colorectal cancer. Higher vitamin D levels have also been associated with decreased mortality from conditions such as cardiovascular disease, stroke, diabetes, and respiratory infections.

Currently, vitamin D supplementation is the most effective and controllable method to achieve and maintain the desired 25(OH)D concentration, especially when sunlight-driven synthesis is limited. The optimal minimal daily dose for healthy adults with normal body weight is approximately 2000 IU (50 µg), which allows reaching serum levels of 30–40 ng/mL with minimal safety risks. Supplementation can be administered daily, weekly (e.g., 15,000 IU), or monthly (e.g., 60,000 IU), with weekly or monthly dosing often improving patient compliance.

Loading doses (“bolus”) given in the first one or two weeks can rapidly raise vitamin D levels, while lower doses maintain a stable concentration over time. This approach enables personalized supplementation, considering the patient’s baseline vitamin D status, lifestyle, and risk factors.

In Hungary, according to the updated 2022 “Hungarian Consensus Recommendation on the Role of Vitamin D in Disease Prevention and Treatment,” recommended vitamin D intake varies by age group. The goal is to maintain serum levels around or above 30 ng/mL, which may contribute long-term to colorectal cancer prevention, treatment, and reduction of recurrence risk.

Additionally, some recent publications highlight vitamin D3 supplementation’s potential benefits in anti-aging and general health maintenance: https://www.independent.co.uk/news/science/vitamin-d3-daily-anti-ageing-b2757496.html 

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"Assessing Your House or Business for Mold...Is There a Right Way?" An Interview with James Weber Specializing in Medically Important Assessment and Remediation...

Having your home or business properly assessed for mold is key in the process that leads to successful remediation, detoxification and recovery from CIRS (Chronic Inflammatory Response Syndrome)...

Kirk Hamilton PAC, Jul 22, 2025

Watch Interview Here
Kirk hamilton pa-c interviews james weber

Specializing in Medically Important Remediation since 2014
James Weber
JW Environmental Remediation Services
11440 Sunrise Gold Cir Suite 24
Rancho Cordova, CA 95742
916-540-8595 / www.jwenviro.com
james@jwenviro.com

Background…
James Weber started in the family carpet cleaning business, which led him to having to deal with a lot of water damaged carpets that eventually led him to remediation of the water damaged or moldy areas. After doing remediation he found that he might get called back because the initial assessment was faulty and other areas of the residence were found to be moldy. This happened frequently enough that led him to start doing the initial assessment himself so as not to waste time and come back and treat more undiscovered mold. Therefore he became involved in not only the remediation or fixing of the mold problem but also the discovery of where “all” of the mold was. He doesn’t do the follow-up testing after remediation to “clear” the residence/building from mold. That is done by a 3rd party.

Medically Important Assessment and Medically Important Remediation…
He uses two terms which are unique - Medically Important Assessment and Medically Important Remediation. Both phrases go beyond just fixing the problem but to do it in a way that the reduces exposure and subsequent medical detoxification which will allow the patient to get well from the conglomeration of systems of what is called “Chronic Inflammatory Response Syndrome (CIRSs).” I encourage you to look at the “Resources for Patients” and the “Resources for Physicians” at SurvivingMold.com. Also I would look at the “Biotoxin Pathway (page 6 diagram)” which gets “triggered” in genetically mold sensitive patients which can result in a wide variety of multiple debilitating symptoms from different organ systems.

How to Test and Which Tests…
The question of if the client should to do “mold” testing is debatable. From listening to James my guess is he would like people to just call him first and tell him about their current situation. It might be cheaper overall for the client do testing after that discussion. The average cost may be around $1500 but that also depends on the size of the house and it’s location which are important factors. The triad of tests that I do (panel #8 $630-675 from Envirobiomics) include the ERMI test for mold, actinomyces and endotoxins is reasonable if you are trying to convince someone there is an issue in their house of toxic compounds that may be making one sick. There are graded scores on each test that suggest the severity of the results. Getting a good amount of dust sample from different areas in the house is important. Air testing and mold plates are problematic and can result in totally missing a moldy situation used by themselves.

Endotoxins can be important as these are organisms that create toxic gases around plumbing.

It is important for an independent third party to test the house right after the remediation is done. James feels there would be a conflict of interest if his company tested for mold right after remediation. The home or residence should be tested 4-6 weeks after the remediation as well.

A big “red flag” for a remediation company is if they use chemicals. James feels strongly the use of chemicals is not necessary or healthful for efficient Medical Important Remediation.

JW Environmental Remediation Services (916) 540-8595 james@jwenviro.com services the Northern California area and sometimes will go out of state.

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Treating the Gut May Be One Answer for Post-Spike Syndrome (PSS) or Covid Long Haul Reports Brazilian Medical Group

Treating gut dysbiosis, reducing inflammation, and a hyperimmune response may resolve symptoms of extreme fatigue, brain fog, neuropathies, and reactivation of prior illnesses...5 case successes... (Watch YouTube Summary of this Research by Kirk Hamilton PA-C)

POST SPIKE SYNDROME (PSS)- DYSBIOSIS - BIFIDOBACTERIA -IVERMECTIN - NATTOKINASE - Post spike syndrome (PSS): Simple solution leading to resolving results, five cases report. ScienceDirect, IDCases, Volume 41, 2025, e02278. Zeballos RS et al.
Kirk’s Commentary: In this article 5 cases of dramatic resolution of systemic diseases are reviewed of females 44-70 years of age, two had both the Covid vaccination and cases of Covid; one had the vaccine and no Covid infection; and two had the Covid infections and no vaccine. The five cases had combined diagnosis of interstitial granulomatous dermatitis, polymyalgia rheumatica, peripheral polyneuropathy, drug-refractory epilepsy and trigeminal neuralgia.

*** HIGHLY RECOMMENDED LISTENING TO DR. PETER MCCULLOUGH INTERVIEWING Dr Roberto Zeballos who is the lead author of the above article from Brazil on the above paper reviewed on the McCullough Report July 14, 2025.

TREATMENT:
1) Four of 5 had 5 days of Cipro 500 mg daily first. The one who didn’t get Cipro because prior to the study period was placed on antibiotics but didn’t tolerate Augmentin but did take moxifloxacin HCL 400 mg for 14 days.
2a) Following the antibiotics was Nattokinase 100 mg twice daily was given for 90 days;
2b) Ivermectin 3 times per week for at least 8 weeks at 6 mg/30 kg (or 6 mg/66 lb; ex. ~130 lb women would take approximately ~ 12 mg daily of Ivermectin);
2c) Bifidobacteria probiotic providing 335 mg twice daily for 90 days (bifidobacter is known to be diminished in Covid patients).
Dr. Zeballo does the above treatment 4-6 weeks. Then he refers his patients to his nutritionist.
3a) Dr. Roberto Zeballos’s Nutritionist
Phase 1 - Diet: 3 days of raw foods - vegetables and fruit, berries, smoothies. eliminates animal protein/just fruit and vegetables.
Phase 2 - Diet next 5 days to 8 weeks a little bit of “protein”, vegetables, raw foods, smoothies, teas.
His nutritionist for 14 days no alcohol, gluten (wheat), dairy, sugar and processed carbohydrate.
3b) Dr. Zeballos recommends vitamin C regularly increases bifidobacteria and vitamin D sometimes. He doesn’t give very many vitamins. He is concerned about gastritis.
3c) Dr. Zeballo’s nutritionist recommends more supplements - beta-glucan, magnesium, selenium, psyllium fiber, bifidobacteria, enzymes, bioflavonoids, macha tea, green tea.
4) Exercise regularly
5) Meditation
6) Dr. Zeballo personally eats for “his body” 5 days a week and 2 days a week he eats for his heart. Small about of alcohol. Takes care of “soul” 2 days per week. Meditates in the sun and exercises.

During the pandemic Dr. Zeballos’s medical group treated more than 11,000 patients. Since January, 2023 they observed a “…surge in Post-Spike Syndrome (PSS) case. The number of cases has continued to rise, and we are currently seeing 3-4 new cases per day.” They have treated over 400 PSS patients in this manner with excellent results.

Conclusion: This is exciting because somehow the gut microbiota is altered by a Covid infection and/or Covid vaccine (or vice versa), with the implication that the spike protein from either is involved in triggering some type of vasculitis, inflammation or hyperimmune response possible through a leaky gut. The antibiotics may wipe out abnormal gut flora and the reinoculation of the bowel with bifidobacteria helps heal the gut and reduce inflammation. The nattokinase may help break down the spike protein, inhibiting clotting and/or vasculitis to some degree, while Ivermectin applies an anti-iflammatory or antiviral effect. Collectively they heal the gut and reinoculate it, reduce the spike protein, inflammation and immune challenge calming down the external illnesses described. You take these above case studies/article in conjunction last week’s interview with pancreatic cancer specialist from Japan, Makoto Abrue, MD, PhD and his paper Repeated COVID-19 Vaccination as a Poor Prognostic Factor in Pancreatic Cancer: A Retrospective, Single-Center Cohort Study and you can see the concern for the continued promotion of the Covid vaccine which delivers an altered spike protein that can “live” in the body for an unknown period of time and cause metabolic dysfunction resulting in other systemic diseases and symptoms. In this Brazilian research as in so many illnesses a healthy gut flora and barrier may help cure or minimize the expression of the disease.

*** HIGHLY RECOMMENDED LISTENING TO DR. PETER MCCULLOUGH INTERVIEWING Dr Roberto Zeballos the lead author of the above article from Brazil on this landmark paper on the McCullough Report July 14, 2025.
References:
Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity.
Cardiac findings in a phase II double-blind randomized placebo-controlled trial of combination therapy (HAZDPac) to treat COVID-19 patients.
Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19).

For Appointments for the treatment of Covid, Covid Long Haul or Post Spike Syndrome, or Post Covid Vaccine problems contact Health Associates Medical Group 916-489-4400 and make an appointment with Kirk Hamilton PA-C.

For the rest of this post for links to "Current Research in Nutrition, Prevention and Integrative Medicine; Cancer and Covid Syndrome News" Click on THIS LINK to Kirk Hamilton’s “Staying Healthy Today” Substack. 

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com