"Clinical Pearls" in Assessing and Treating 'Spike Protein' Heart Related Conditions in the Era of Covid Vaccines and Infections - An Interview with Cardiologist Dr. Peter McCullough

Peter A. McCullough™, MD, MPH
6320 LBJ Freeway, Suite 221
Dallas, Texas 75240
Office: 214-272-7707 / Fax: 214-272-0462
‍petermcculloughmd@gmail.com

Kirk Hamilton PAC Interviews Peter A. McCullough™, MD, MPH on Spike Protein Related Heart Conditions from a Covid Infection, Covid Vaccination or Both
Watch Video Interview Here (55:10 min)

Dr. McCullough is an internist, cardiologist, epidemiologist holding degrees from Baylor University, University of Texas Southwestern Medical School, University of Michigan, and Southern Methodist University. Dr. McCullough has broadly published on a range of topics in medicine with > 1000 publications and > 700 citations in the National Library of Medicine. Dr. McCullough is a well-known public figure in medicine and is a frequent contributor on numerous mainstream and independent media platforms. He has testified multiple times in the US Senate, US House of Representatives, European Parliament, and many state capitals concerning public health policy.

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Otter.AI Generated Transcript Highlights with Peter McCullough MD and Kirk Hamilton PAC (edited by Kirk Hamilton PAC)

Overview

  • Prescribe colchicine 0.6 mg/d for 1 year and recommend the Ultimate Spike Detox supplement for patients with mild pericarditis or subclinical myocarditis.

  • Encourage patients to sweat regularly through exercise or infrared sauna to help eliminate spike protein from the body.

  • Kirk discusses his personal journey of treating himself for Covid and others using The McCullough Protocol™ and FLCC (Independent Medical Alliance IMA) protocols.

  • Kirk's personal cancer journey is mentioned and Dr. McCullough asks about Kirk Hamilton’s alternative treatments using repurposed drugs (ivermectin, mebendazole), nutraceuticals, IV therapy and meditation.

  • Kirk recounts his diagnosis of colon cancer in September of 2023 and his decision to use repurposed drugs, nutraceuticals, IV vitamin C and meditation for treatment.

  • He describes his experience with ivermectin and hydroxychloroquine as preventive measures before getting COVID-19 vaccines in January and February 2021.

  • He discusses the challenges and successes of his treatment, including tumor size not decreasing but no metastases and eventually undergoing surgery of a 8 cm mass with no cancer spread.

  • Dr. McCullough's shares insights on Spike Protein and Cancer.

  • Dr. McCullough explains the long-term nature of colon cancer and the impact of Kirk's lifestyle changes and stress during the pandemic.

  • Kirk shares his experience with ivermectin “overdose” and its side effects, including visual disturbances and syncopal episodes at doses between 2-4.5 mg/kg of Ivermectin.

  • They discuss the importance of monitoring spike protein antibodies and the use of the Ultimate Spike Detox for treatment.

Treatment Approaches and Nutraceuticals

  • Dr. McCullough outlines the use of the Ultimate Spike Detox and other nutraceuticals like nattokinase, bromelain, and curcumin for spike protein detoxification. Standard dose 2 tablets twice daily on empty stomach. Watch for bruising.

  • Kirk shares his current treatment regimen, including the use of the Ultimate Spike Detox and additional nutrients.

  • Dr. McCullough and Kirk Hamilton PA discuss the importance of taking the Ultimate Spike Detox on an empty stomach and the potential for bruising due to high doses of nattokinase.

  • Dr. McCullough emphasizes the role of enzymes like nattokinase in breaking down the spike protein and bromelain may add to the blood thinning and bruising effect.

Cardiovascular Conditions and Spike Protein

  • Dr. McCullough explains the impact of the spike protein on cardiovascular conditions, including myocarditis, pericarditis, and atrial fibrillation.

  • He describes the common symptoms of myopericarditis and the importance of using the Ultimate Spike Detox 4-8 capsules daily (watching for bruising) and colchicine at 0.6 mg/d for treatment. Colchicine is a powerful anti-inflammatory agent. It should be given for a year with the Ultimate Spike Detox.

  • They discuss the use of blood tests like D-dimer (clotting), troponin (heart muscle damage), galectin-3 (marker of heart tissue fibrosis), BNP (heart failure), and CRP (inflammation) for detecting vascular injury myocarditis/pericarditis.

  • Dr. McCullough highlights the role of the spike protein in causing blood clots and the need for blood thinners in combination with the Ultimate Spike Detox (again being aware of bruising to reduce dose).

Nutraceutical Support for Heart Conditions

  • Dr. McCullough recommends nutraceuticals like CoQ10 (800 mg/d), L-carnitine (500 mg/d), selenium (200 mcg/d), B vitamins (especially thiamine), and beet root extract for heart health (Healthy Heart)

  • He discusses the importance of magnesium malate (800-1200 mg/d) for controlling atrial fibrillation (Ultimate Spike Detox and colchicine 0.6 mg/d)

  • Dr. McCullough emphasizes the important of exercise and sweating in detoxifying the spike protein.

  • Dr. McCullough emphasizes the need for a comprehensive approach to treating spike protein-related cardiovascular conditions, including lifestyle changes and nutraceutical support.

Future of Vaccines and Immunizations

  • Dr. McCullough expresses his belief that the COVID-19 vaccines will not be pulled off the market despite their disastrous results. He notes people are not taking them anymore.

  • He discusses the rising rate of autism and the potential link between vaccines and autism.

  • They mention the recent press conference by Trump and RFK today and the ongoing debate about the safety of vaccines and immunizations.

  • Dr. McCullough shares his personal decision to stop taking vaccines and his advice to his son, who is in medical school, to avoid them.

Conclusion and Final Thoughts

  • Kirk thanks Dr. McCullough for his insights and contributions to the discussion.

  • They emphasize the importance of sharing credible information about spike protein-related diseases and the negative impact of vaccines.

  • Dr. McCullough reiterates the need for a holistic approach to treating spike protein conditions, including lifestyle changes, nutraceuticals, and medical interventions.

  • Kirk concludes the interview by expressing his gratitude and encouraging listeners to seek out reliable information and support and above links to educational resources.

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Highlights…

ALZHEIMER’S DISEASE - BLOOD TEST - Phosphorylated Tau-217 - New Blood Test for Preclinical Alzheimer's Disease. Available at Lab Corp, Phosphorylated Tau-217 had 79% Positive Predictive Value. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Sep 20, 2025.
1) Plasma Phosphorylated Tau 217 to Identify Preclinical Alzheimer Disease.
2) Lab Corp - Lumipulse® pTau-217/Beta Amyloid 42 Ratio, Plasma, Test Number 505809

BANNING COVID VACCINES - TWO SURGEON GENERALS - Two Surgeon Generals Now Stand on the Right Side of History. Florida’s Dr. Joseph Ladapo is no longer alone — Louisiana’s Dr. Ralph Abraham has now joined him in warning against deadly COVID mRNA shots. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 13, 2025.

COVID 19 SPIKE PROTEIN ANTIBODY TESTING - LAB CORP ON DEMAND - TEST NUMBER 164090 COVID 19 ANTIBODY TEST - 86769 Dr. Peter McCullough explains test and need for it as well at “Ultimate Spike Protein Detoxification (video 5:05 min:sec)

SPIKE PROTEIN DETOX - Discover the Spike Protein Detox Guide – by World Council for Health. A digest of the latest knowledge and insights, informed by ethical scientists, independent researchers and health practitioners. World Council for Health, Sep 20, 2025. SPIKE PROTEIN DETOX GUIDE.

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Nutrition, Prevention and Integrative Medicine…

 ADDICTION - CANNABIS - High-THC Cannabis Products Linked to Immediate Psychosis and Addiction. The link is based on a new review of 99 studies involving more than 220,000 people. George Citroner, EPOCH Times, 9/19/2025.

AGING - Strength Training Linked To Longer Telomeres & Slower Aging, By Ava Durgin, MindBodyGreen, September 19, 2025.
1) Telomere Length and Biological Aging: The Role of Strength Training in 4814 US Men and Women. “…adults who strength trained regularly had significantly longer telomeres and therefore less biological aging than adults who did not strength train…”

AUTISM - CHILDHOOD VACCINES - Compelling scientific evidence that vaccines currently used worldwide cause Autism Spectrum Disorder was presented at CONBRAIM in Brazil this month. Expert Brazilian neurologist and researcher, Professor Cicero Coimbra, says it is urgent that we acknowledge that vaccines cause Autism and put a stop to childhood vaccination. Tess Lawrie, MBBCh, PhD​, Aug 28, 2025.

BRAIN DAMAGE - CELL PHONES - NEW STUDY: Cell Phone Radiation at 20× Below Legal Limit Induced Brain Damage in Rats. Infant rats exposed to “safe” cell phone radiation levels suffered impaired neuronal development and disrupted brain chemistry, while parallel in-vitro tests showed DNA damage in neural stem cells. Nicolas Hulscher, MPH, Courageous Discourse, Sep 20, 2025.

COGNITIVE DECLINE - Flavonoids May Help Prevent Cognitive Decline, Research Shows. By Hannah Frye, MindBodyGreen, September 7, 2025.
1) Dietary (Poly)phenols and Cognitive Decline: A Systematic Review and Meta-Analysis of Observational Studies.
2) Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits.
3) Enhancing the Cognitive Effects of Flavonoids With Physical Activity: Is There a Case for the Gut Microbiome?
4) Anti-Inflammatory Effects of Flavonoids in Common Neurological Disorders Associated with Aging.

COGNITIVE DECLINE - SLEEP - Chronic insomnia may raise dementia risk by 40%, lead to 3.5 years faster aging. Corrie Pelc, Medical News Today, September 12, 2025

DEMENTIA - FIBER - Increase Your Fiber Intake To Reduce Your Risk Of Disabling Dementia. Morgan Chamberlain, MindBodyGreen, August 19, 2025.
1) Dietary fiber intake and risk of incident disabling dementia: the Circulatory Risk in Communities Study. “…Conclusions: Dietary fiber intake, especially soluble fiber, was inversely associated with risk of disabling dementia in a general Japanese population…”

FERTILITY - SPERM COUNTS - COVID 19 - COVID-19 infection was associated with poor sperm quality: a cross-sectional and longitudinal clinical observation study. “…This study was designed to determine whether COVID-19 affects sperm quality in men and to identify which sperm parameters were affected…our study showed that COVID-19 was associated with poor sperm quality manifested by reduced sperm count and sperm motility, and increased sperm DNA fragmentation…” PDF

HOMOCYSTEINE - AORTIC STIFFENING. Homocysteine leads to aortic stiffening in a rabbit model of atherosclerosis.

IMMUNITY - GUT HEALTH - How Gut Bacteria Shape Your Brain, Immunity, and Mental Wellness | Dr. Sabine Hazan. Jan Jekielek, American Thought Leaders, September 2025.

MARIJUANA - CANNABIS - ADDICTION - TCH - High-THC Cannabis Products Linked to Immediate Psychosis and Addiction. The link is based on a new review of 99 studies involving more than 220,000 people. George Citroner, The Epoch Times, 9/19/2025.
1) High-Concentration Delta-9-Tetrahydrocannabinol Cannabis Products and Mental Health Outcomes: A Systematic Review.

SSRI DANGERS - TAPERING - SSRI Dangers & Tapering Off Safely with Dr. Josef Witt-Doerring Hosts Dr. Paul Marik and Dr. Joseph Varon are joined by psychiatrist Dr. Josef Witt-Doerring to unpack persistent myths around SSRIs, the realities of withdrawal, and why depression care must evolve. Independent Medical Alliance, Sep 12, 2025.

VACCINATION - EMPLOYMENT - SCHOOL REQUIREMENTS - NEED FOR - End of School and Employment Vaccine Requirements Coming? Florida Move Could Undo the Entire Enterprise. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Sep 21, 2025.
1) Florida moves to be the first US state to end vaccine mandates.

VACCINE INJURY - Childhood Vaccine Injuries - 1 year old Devan stopped breathing after (DKTP-Hib-HepB and Pneu Vaccines). William Makis, MD, Sep 13, 2025.

VACCINE INJURY - CHILDHOOD - Senate Hearing Exposes Study Showing Vaccinated Children Have 2.5x Higher Rates of Chronic Illness. Senate testimony reveals how a comprehensive vaccinated vs. unvaccinated study was suppressed when results didn’t align with public health messaging. See the data they didn’t want released. Independent Medical Alliance, Sep 13, 2025.

VACCINE VALIDITY - Vaccine-induced chronic disease on front burner in Washington, Dr. Peter McCullough, The McCullough Report, Mon Sep 15, 2025.

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Cancer…

 BLADDER CANCER - COVID VACCINE - First Direct Evidence of mRNA "Vaccine" Genomic Integration Identified in Stage IV Cancer Patient. Vaccine DNA plasmid-derived Spike gene sequence integrated into chromosome 19 with perfect 20/20 bp identity — accompanied by widespread genomic dysfunction. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 15, 2025.
1) Genomic Integration and Molecular Dysregulation in Aggressive Stage IV Bladder Cancer Following COVID-19 mRNA Vaccination.

BLADDER - SMALL CELL CARCINOMA - IVERMECTIN and FENBENDAZOLE Testimonial - 57 year old Chicago man with Stage 4 Small Cell Carcinoma of the Bladder - cancer free after 2 months! William Makis, Covid Intel, Sep 20, 2025.

BREAST CANCER - IVERMECTIN and MEBENDAZOLE and DMSO Testimonial. 34 year old Pennsylvania woman with Stage 4 Breast Cancer metastatic to brain, lung, liver, spine, has incredible results after 3 months! William Makis, MD, Covid Intel, Sep 21, 2025.

CANCER - DIET GUIDELINES - KETOGENIC - SUGAR - Dietary Interventions in Cancer: Targeting Tumor Metabolism Through Diet. The latest cancer treatment guide from Dr. Paul Marik outlines how ketogenic diets, intermittent fasting, and glucose tracking can support therapy, weaken tumors, and improve outcomes. Paul Marik, Independent Medical Alliance, Sep 20, 2025.
1) Dietary Interventions in Cancer. “…“If you starve the cancer cell of glucose and carbohydrate, it prevents or limits proliferation. It reduces metastases.” — Dr. Paul Marik, IMA Chief Scientific Officer…”
2) Cancer Care: The Role of Repurposed Drugs and Metabolic Interventions in Treating Cancer.
3) The Approach to Repurposed Drugs for Cancer.
4) The 10 Deadliest Cancers—and How to Stop Them.
5) Targeting Cancer Stem Cells.
6) Preoperative Repurposed Drugs.

CARDIAC ARREST - COVID VACCINATION - Saudi Study Links Covid ‘Vaccines’ to Surge in Sudden Cardiac Arrests Among Young People. William Makis, Covid Intel, Sep 15, 2025.
1) Myocarditis and Pericarditis Following the COVID-19 Vaccination: A Single-Center Case Series.

COLON CANCER - FENBENDAZOLE - CBD - Testimonial - 40 year old British man with terminal Stage 4 Colon Cancer made it into mainstream media. William Makis, MD, Covid Intel, Aug 27, 2025.

COLON CANCER - IVERMECTIN - FENBENDAZOLE Testimonial - 34 year old man from Slovenia with Stage 4 Colon Cancer reports after 3 months: CEA 679 to 10, up to 50% tumor shrinkage after starting! William Makis, MD, Covid Intel, Sep 22, 2025.

HEART TUMOR - Heart Tumors Loaded with Spike Protein. Pandemic Neoplasms Must be Stained for SARS-CoV-2 Spike Protein. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Sep 16, 2025.

IVERMECTIN and FENBENDAZOLE - Testimonial - 75 year old Southern Florida man with Stage 4 Renal Cell Carcinoma sees dramatic improvement after 6 months. William Makis, MD, Covid Intel, Aug 28, 2025.

PANCREATIC CANCER - IVERMECTIN and FENBENDAZOLE Testimonial - 64 year old Ontario man with Stage 4 Pancreatic Cancer to liver has incredible response after 2 months, CA19-9 down 93%. William Makis, Covid Intel, Aug 28, 2025.

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Covid Syndrome…

 COVID VACCINATION - DETOXIFICATION - LIPID NANO PARTICLES -MasterPeace® Study - Detoxification Support Colloid Found to be Effective in Removing Bluetooth Signals from the Human Body Field Tests and Analysis at Radlett, Hertfordshire, UK — April to June 2025 By the MasterPeace Research Team.
1) Study On The Electromagnetism Of Vaccinated Persons In Luxembourg.

COVID VACCINATION - JAPAN - DEATH FROM - Japan Confirms Over 600,000 Citizens Killed by Covid ‘Vaccines’(600,000 citizens) William Makis, MD, Covid Intel, Sep 22, 2025.
1) National Coalition to Stop mRNA Vaccines.
2) Japan Confirms Covid 'Vaccines' Have Now Killed Over 600,000 Citizens.
3) Japan Warns New Covid ‘Replicon Vaccines’ Are ‘Third Atomic Bomb’.

COVID VACCINATION - FERTILITY - Nic Hulscher: Unveiling mRNA’s Impact on Fertility and Health. Decoding the science of mRNA’s health crisis. The Truth Contract and DCMC, Sept 16, 2025.
1) Autopsy findings in cases of fatal COVID-19 vaccine-induced myocarditis.
2) Covid-19 vaccination BNT162b2 temporarily impairs semen concentration and total motile count among semen donors.
3) Impact of mRNA and Inactivated COVID-19 Vaccines on Ovarian Reserve.
4) Temporal trends in sperm count: a systematic review and meta-regression analysis.
5) Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic.
6) Expression of SARS-CoV-2 spike protein in cerebral Arteries: Implications for hemorrhagic stroke Post-mRNA vaccination.
7) Association Between COVID-19 Vaccination and Neuropsychiatric Conditions.

COVID VACCINATION - HEART ATTACK - Can COVID-19 - Vaccination Provoke a Heart Attack? Grant Stinchfield Asks About his Vaccinated Friend. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Sep 17, 2025.
1) Association of SARS-CoV-2 immunoserology and vaccination status with myocardial infarction severity and outcome.

COVID VACCINATION - NEUROLOGIC DISEASE - COVID-19 "Vaccines" Linked to 63 Serious Central Nervous System Adverse Events. CDC/FDA safety thresholds breached as COVID shots disrupt the blood–brain barrier, unleashing meningitis, encephalitis, prion disease, brain abscesses, herpes reactivations, and more. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 17, 2025.
1) COVID-19 mRNA Vaccination: Implications for the Central Nervous System.

COVID VACCINATION - New Study Obliterates the "Millions Saved" COVID Shot Myth. Peer-reviewed analysis exposes how the vaccine cartel propped up its fraudulent talking point — “millions of lives saved” — with computer models, false assumptions, and censorship. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 17, 2025.
1) A Step-by-Step Evaluation of the Claim that COVID-19 Vaccines Saved Millions of Lives.

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Societal and World Health…

 ORGAN HARVESTING (FORCED) - CHINA - RUSSIA - Xi and Putin’s Hot Mic Moment on Immortality and Why It Matters | Joshua Philipp, Jan Jekielek, American Thought Leaders, Sep 16, 2025. Video.

PEACE - DIALOGUE - DIFFERENT OPINION - Why Charlie Kirk’s Approach Matters Now More Than Ever | Pastor Jackson Lahmeyer, Jan Jekielek, American Thought Leaders, Sep-20-2025.

POPULATION - CRISIS - WORLD INFERTILITY - An Impending Population Crisis? World Fertility Rate Hits 60-Year Low. The decline in fertility, which began in the 1960s, coincided with societal change including rising divorce rates and legalized abortion. Sylvia Xu, EPOCH Times, September 19, 2025

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Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

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Nutrition, Prevention, & Integrative Medicine Research: September 11, 2025

Highlights…

VACCINES - - FLORIDA - MANDATORY - Dr. Joseph Ladapo Leads a Reformation. The Florida Surgeon General pledges to end vaccine mandates, thereby affirming the primacy of liberty in the United States. John Leake, Focal Points (Courageous Discourse), Sep 07, 2025. “…I think it’s a marvelous twist of history that we needed a young man from Nigeria to remind us that, here in the United States, we value individual liberty over the protections promised by a paternalistic state…” Vaccines: Mythology, Ideology, and Reality Hardcover – July 29, 2025 by John Leake (Author), Peter A. McCullough MD MPH (Author)

ORGAN TRANSPLANTATION - FORCED - CHINA - XI - PUTIN - Xi, Putin Caught on Hot Mic Discussing Immortality Plan Involving Organ Transplants. Joshua Philipp, Crossroads, EPOCH Times, September 4, 2025.

LONG COVID - COVID 19 VACCINE - YALE RESEARCHERS - Long COVID Hoax? Yale Researchers Find Symptoms Caused by ‘Toxic’ Vaccine Spike Protein, Dr. William Makis MD, Covid Intel, Sep 07, 2025.
1) Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination. “…Summary: COVID-19 vaccines have prevented millions of COVID-19 deaths. Yet, a small fraction of the population reports a chronic debilitating condition after COVID-19 vaccination often referred to as post- vaccination syndrome (PVS). To explore potential pathobiological features associated with PVS, we conducted a decentralized, cross-sectional study involving PVS participants and 22 healthy controls enrolled in the Yale LISTEN study. Compared with controls, PVS participants exhibited differences in immune profiles, including reduced circulating memory and effector CD4 T cells (type 1 and type 2) and an increase in TNFα+ CD8 T cells. PVS participants also had lower anti-spike antibody titers, primarily due to fewer vaccine doses. Serological evidence of recent Epstein-Barr virus (EBV) reactivation was observed more frequently in PVS participants. Further, individuals with PVS exhibited elevated levels of circulating spike protein compared to healthy controls. These findings reveal potential immune differences in individuals with PVS that merit further investigation to better understand this condition and inform future research into diagnostic and therapeutic approaches…”

VACCINE HARM - BREAKING: Henry Ford Birth Cohort: Vaxxed vs. Unvaxxed, Reported Vaccinated Kids Had 453% More Neurodevelopmental Disorders — 57% Rendered Chronically Ill. The largest vaccinated vs. unvaccinated birth cohort study in U.S. history (n=18,468) tracked children for 10 years — and revealed staggering increases in chronic disease among the vaccinated. Nicolas Hulscher, MPH, Focal Point (Courageous Discourse), Sep 09, 2025. How the Corruption of Science has Impacted Public Perception and Policies Regarding Vaccines, September 9, 2025, 2:00pm, Senate Hart Building, SH-216. Video.

VACCINE - SAFETY - SIDE EFFECTS - Trump Posts Vaccines Are Poison As Historic Henry Ford Birth Cohort Study Proves Irrefutable Vaccine Harms. The Beginning of the End for Vaccine Ideology — Nicolas Hulscher on Brannon Howse Live Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 10, 2025.

(GO tO kIRK’S cOMPLETE SUBSTACK FOR SEPTEMBER 11, 2025)

Nutrition, Prevention and Integrative Medicine…

 HAIR GROWTH - NUTRIENTS - 7 Nutrients To Get More Of If You're Dealing With Hair Loss, By Morgan Chamberlain, MindBodyGreen, July 09, 2025.

MACULAR DEGENERATION - RESTLESS LEG SYNDROME - IVERMECTIN and FENBENDAZOLE Testimonial - 88 year old woman has improving Macular Degeneration, blindness in one eye, and Restless Leg Syndrome! William Makis, MD, Covid Intel, Sep 06, 2025.

MICROBIOME - GUT HEALTH - SYSTEMIC DISEASE - How Gut Bacteria Shape Your Brain, Immunity, and Mental Wellness | Dr. Sabine Hazan. Jan Jekielek, American Thought Leaders. September 9, 2025.

MYASTHENIA GRAVIS - THYMOMA - IVERMECTIN and FENBENDAZOLE Testimonial - 41 year old man in Japan with Thymoma and Myasthenia Gravis sees improvement in both after 3 months! William Makis, MD, Covid Intel, Sep 06, 2025.

PSORIASIS - IVERMECTIN and FENBENDAZOLE Testimonial - 43 year old Canadian man clears his PSORIASIS in 3 months! William Makis, MD, Covid Intel, Sep 07, 2025.

VACCINE EFFICACY - FLU VACCINE - CLEVELAND CLINIC - Effectiveness of the Influenza Vaccine During the 2024-2025 Respiratory Viral Season. “…Conclusions This study found that influenza vaccination of working-aged adults was associated with a higher risk of influenza during the 2024-2025 respiratory viral season, suggesting that the vaccine has not been effective in preventing influenza this season…” “…Summary Among 53402 working-aged Cleveland Clinic employees, we were unable to find that the influenza vaccine has been effective in preventing infection during the 2024-2025 respiratory viral season…”

VACCINE HARM - Trump Posts Vaccines Are Poison As Historic Henry Ford Birth Cohort Study Proves Irrefutable Vaccine Harms. The Beginning of the End for Vaccine Ideology — Nicolas Hulscher on Brannon Howse Live. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 10, 2025.

VACCINE HESITANCY - Vaccine Hesitancy: "A Disease of the Mind". Vaccinology Defines A New Mental Illness to be Targeted by Weapons of Public Health. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Sep 05, 2025.
1) Vaccines: Mythology, Ideology, and Reality Hardcover – July 29, 2025, by John Leake (Author), Peter A. McCullough MD MPH (Author)

VACCINE SAFETY - Weighing mRNA Vaccines, POTUS Should Rely on Senate and House Hearings, Not Drug Companies. Stinchfield Asks Dr. McCullough if Trump Has Finally Awoken? Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Sep 10, 2025.

VACCINE SAFETY - RESPIRATORY SYNCYTIAL VIRUS (RSV) - RSV Shots Linked to Over 200 Safety Signals — Serious Neurological, Cardiac, and Pregnancy Harms Identified. New VAERS study finds major signals for fetal death, preterm birth, paralysis, Guillain-Barré syndrome, heart failure, thrombocytopenia, and mini-strokes. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Sep 05, 2025.
1) Post-marketing safety monitoring of RSV vaccines: A real-world study based on the Vaccine Adverse Event Reporting System (VAERS). “…We have described notable reporting patterns related to RSV vaccines using real-world data from VAERS. For protein sub unit vaccines (RSVPreF3 and RSVpreF), disproportionately elevated reporting was observed for inflammatory neurological events (e.g., GBS, facial paralysis), immune thrombocytopenia, and atrial fibrillation – AEs that are clinically significant and merit further investigation, especially in older adults…”

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Cancer…

BREAST CANCER - IVERMECTIN and MEBENDAZOLE Testimonial - 53 year old Canadian woman with Stage 2 Breast Cancer TNBC with 7.8cm tumor, has no cancer on surgical pathology 7 months later (photos) !!! Dr. William Makis MD, Covid Intel, Sep 05, 2025.

BREAST CANCER - IVERMECTIN and FENBENDAZOLE - Testimonial - 49 year old Australian woman with Stage 4 Breast Cancer is cancer free after 6 weeks! William Makis, MD, Covid Intel, Sep 09, 2025.

COLON CANCER - CRUCIFEROUS VEGETABLES - Cruciferous vegetables intake and risk of colon cancer: a dose–response meta-analysis. “…This meta-analysis confirms a nonlinear inverse dose–response relationship between cruciferous vegetable intake and colorectal cancer risk, with significant risk reduction initiating at ≥ 20 g/d…The primary inverse association (OR = 0.80, 95%CI 0.72–0.90) remained robust in sensitivity analyses…”

COLON CANCER - GASTRIC CANCER - IVERMECTIN, FENBENDAZOLE and METHYLENE BLUE Testimonial - Stage 4 Colon and Gastric Cancer patient with 12-19 months to live, is now Cancer Free! Dr. William Makis MD, Covid Intel, Sep 04, 2025.

COLON CANCER - INCREASE - 2021 - Colon cancer on the rise since 2021. And it's happening in young kids. Jessica Rose, Unacceptable Jessica, Sep 07, 2025.

RECTAL CANCER - IVERMECTIN and FENBENDAZOLE Testimonial - 49 year old woman from Slovakia with Stage 3 Rectal Cancer sees improvement in 2 months and is eligible for surgery. William Makis, MD, Covid Intel, Sep 10, 2025.

Covid Syndrome…

COVID VACCINE - DIED SUDDENLY - mRNA Injury Stories - 27 year old Dr.Dustin Gregory Moore MD died suddenly on March 24, 2025, William Makis, MD, Covid Intel, William Makis, MD, Sep 10, 2025.

COVID VACCINE - PFIZER - KNOWN SIDE EFFECTS - "Dr. Naomi Wolf Brings The Pfizer Papers Findings to the European Parliament". Opinion - Naomi Wolf.D r Naomi Wolf, Sep 06, 2025.

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Societal and World Health…

CDC - POLICY - What’s Really Happening at the CDC? | Dr. Robert Malone, American Thought Leaders, Jan Jekielek, EPOCH Times, Sep-04-2025.

GIO POLITICS - VACCINES - TRUMP - GATES - RFK - EPSTEIN - Trump and Gates Celebrate Partnership. RFKjr says Trump Should get Nobel Prize. Michael Yon, Michael’s Newsletter, Sep 04, 2025.

VIOLENCE - SOCIETAL HEALTH - A Murder That Says So Much About U.S.. Slaughter of a Ukrainian girl on a Charlotte, NC light rail train shows what a shabby horror show U.S. cities have become. John Leake, Focal Points (Courageous Discourse), Sep 07, 2025.

Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

 

Do Patients With Endometriosis Have Impaired Intestinal Permeability?

Do Patients With Endometriosis Have Impaired Intestinal Permeability Compared to Healthy Controls and Patients with Pelvic Pain Without Endometriosis?

Substack Video Kirk Hamilton PAC Interview Shanti Mohling, MD 46:36 min:sec
Shanti Mohling, MD, FACOG
Northwest Endometriosis and Pelvic Surgery
511 SW 10th Ave, Suite 907, Portland, OR 97205
503-715-1377 / Fax 503-715-2717
Shantimohling@gmail.com

“Intestinal permeability and endometriosis: a pilot investigation ”
Journal of Endometriosis and Uterine Disorders,
September 2023, Volume 3,100045 9/2025
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Kirk’s Comments on Interview…

Fond Memories of the Power of Food Elimination…
I was very excited about this interview because it reinforced a major belief and long-standing practice of mine as an integrative medicine physician assistant: that individual foods—or patterns of food consumption—can cause virtually any symptom, symptom complex, or systemic disease.

This understanding dates back to my very first job as a physician’s assistant in an integrative medicine practice in May 1983, where nearly every patient was placed on a two-week “detox.” The protocol consisted of a green smoothie (with psyllium seed husks and basic vitamins) and daily coffee enemas to “stimulate” liver detoxification. Nothing else was eaten. I remember it well—it was a kind of slimy, green drink.

The bottom line was simple: patients were removed from their usual food patterns. Most patients came in with multiple complaints, often linked to unhealthy diets. Or others ate what seemed like a pristine diet but regularly consumed one or two foods that “looked healthy” but triggered sensitivity—such as eggs, sprouted grain bread, sourdough, yogurt or coffee (it could be any frequently eaten whole food…). One person’s health food could easily be another’s source of chronic symptoms.

In just six months at that practice, I witnessed nearly every patient experience improvements in their symptoms or disease complex during or after this two-week elimination diet. It didn’t matter what their initial complaints were—almost always, something improved.

Working Hypothesis…
My working hypothesis is that removing the patients “normal foods” (some offending?) gave the gut time to heal. Most gut cells from the stomach to rectum take somewhere between 3–7 days to regenerate. Intestinal permeability can improve from weeks to months. I suspect that excessive antigen uptake that fuels immune activation was reduced immediately by eliminating commonly eaten offending foods, and, over time as intestinal permeability was reduced. This “quieted” the immune system and lead to symptom relief—sometimes immediately, sometimes after weeks or months on a low “food intolerance” regimen.

The “magic” wasn’t just in food removal; it was in the gut’s opportunity to repair itself. Depending on diet and fiber intake, the microbiome (intestinal bacteria) can take months to re-balance which is where systemic disease can be slowed, stopped or even reversed.

What Do Food Sensitivities or Diet Have to Do with Endometriosis?…
This experience is directly relevant to Dr. Mohling’s research. She and her colleagues found a significantly higher degree of intestinal permeability in patients with endometriosis compared to those with pelvic pain alone or healthy controls.

This suggests that food—directly or indirectly, through intestinal permeability and microbiome disruption—“may” play a role in triggering or healing endometriosis (or symptom reduction) in susceptible individuals.

The key question is whether increased intestinal permeability precedes endometriosis or is a consequence of the disease. It may be both: a contributing factor and a byproduct, creating a vicious cycle.

Endometriosis Tissue: Similar but Not the Same…
Dr. Mohling explained a compelling hypothesis: that endometrial-like tissue outside the uterus may originate during gestation. This tissue is similar to, but not identical with, uterine endometrial lining. When exposed to inflammatory cytokines, it can become symptomatic endometriosis in and around the abdominal cavity and organs.

Rather than relying solely on the retrograde menstruation theory, this explanation offers a clearer mechanism: physiologic events such as increased intestinal permeability or altered microbiota may drive inflammation that stimulates these ectopic tissues.

Kirk’s “Mile High View”…
The bigger picture is that intestinal permeability and microbiome disruption may underlie not only endometriosis but also many chronic systemic illnesses. The specific symptoms differ, but the pathophysiology is similar: food (or medication) consumption → increased intestinal permeability → microbiome disruption → inflammatory mediator release → chronic disease.

So, while Dr. Mohling’s findings are directly relevant to endometriosis, they also apply broadly to many chronic conditions that conventional medicine struggles to manage.

That said, Dr. Mohling is clear: for significant endometriosis, surgery is usually necessary to achieve meaningful symptom relief. Lifestyle measures are supportive but rarely sufficient on their own.

Lifestyle Strategies for Endometriosis…
In addition to a whole-food diet rich in fruits, vegetables, protein, and cultured dairy, Dr. Mohling recommends:

  • Vitamins C, D, and E

  • NAC (N-acetylcysteine)

  • Omega-3 fatty acids

  • Magnesium

  • Probiotics

  • Palmitoyl ethanolamide (PEA) — which Dr. Mohling was particularly enthusiastic about

I would also suggest:

  1. Assessing for bacterial or yeast/fungal overgrowth, or doing a therapeutic antifungal trial over 2-4 weeks if indicated by extensive antibiotic history.

  2. Incorporating periodic fasting, such as the Prolon Fasting Mimicking Diet (five days a month for 6–12 months) to reduce immune activation and inflammatory mediators.

  3. Considering supervised water fasting programs at centers like TrueNorth Health Center for carefully selected patients for 1-2 weeks.

Kirk Hamilton PA-C

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Otter.AI Generated Interview Transcript Summary

Overview…
Dr. Shanti Mohling, an OB-GYN surgeon, discussed her study on intestinal permeability in patients with endometriosis, published in the Journal of Endometriosis and Pelvic Pain Disorders. The study found that 50% of endometriosis patients had intestinal permeability, compared to none in healthy controls and 10% in those with pelvic pain but no endometriosis. Dr. Mohling emphasized the importance of lifestyle changes, including a diet rich in fruits, vegetables, and lean proteins, and the use of supplements like omega-3, vitamin D, and NAC. She also highlighted the need for surgery to manage endometriosis effectively.

Introduction and Background of Dr. Shanti Mohling…

  • Kirk Hamilton introduces himself and the show’s focus on endometriosis and intestinal permeability.

  • Dr. Shanti Mohling, an OB-GYN surgeon, is introduced as the guest.

  • Dr. Mohling shares her background, including her education in massage therapy and her transition to medical school.

  • Dr. Mohling discusses her current focus on surgical management of endometriosis in Portland, Oregon.

Understanding Endometriosis and Its Etiology…

  • Dr. Mohling explains the etiology of endometriosis, emphasizing that it is not fully understood.

  • She describes the theory of retrograde menstruation and the role of unhealthy peritoneal fluid in endometriosis.

  • Dr. Mohling highlights the importance of a healthy internal environment in managing endometriosis.

  • Kirk Hamilton asks for clarification on endometriosis, and Dr. Mohling explains the process of endometrial tissue possibly migrating outside the uterus and/or the endometrial-like tissue was already present outside the uterus but do to multiple triggering factors caused the manifestation of the disease which could be the result of increased intestinal permeability or the disease process might increase intestinal permeability.

Intestinal Permeability and Endometriosis…

  • Dr. Mohling discusses her study on intestinal permeability and endometriosis, noting that half of the patients with endometriosis also had increased intestinal permeability.

  • She explains that intestinal permeability can be transient and can improve with dietary changes.

  • Dr. Mohling emphasizes the association between intestinal permeability and endometriosis, but not the causality.

  • Kirk Hamilton and Dr. Mohling discuss the inflammatory nature of endometriosis and its impact on pain.

Prevalence and Impact of Endometriosis…

  • Dr. Mohling estimates that 10% of females have endometriosis, which can range from mild to severe.

  • She describes the debilitating effects of endometriosis, including severe dysmenorrhea, infertility, and fibrotic lesions.

  • Dr. Mohling explains how endometriosis can manifest with IBS-like symptoms and debilitating cramping pain.

  • Kirk Hamilton asks about the symptoms of endometriosis, and Dr. Mohling emphasizes the importance of recognizing severe menstrual cramps, especially those that result in an emergency room visit for pain control.

Lifestyle and Dietary Recommendations for Endometriosis

  • Dr. Mohling recommends a diet rich in fruits, vegetables, and lean proteins to improve gut health and manage endometriosis.

  • She advises limiting processed foods, sugar, and alcohol to support gut health.

  • Dr. Mohling discusses the importance of a balanced diet, including moderate dairy products and cultured dairy.

  • She highlights the role of supplements like omega-3 fatty acids, vitamin D, vitamin C, and NAC in managing endometriosis.

Role of Surgery and Lifestyle Changes in Managing Endometriosis

  • Dr. Mohling emphasizes the importance of surgery in removing endometriotic lesions but also stresses the need for lifestyle changes.

  • She discusses the impact of long-term use of NSAIDs and the development of intestinal permeability.

  • Dr. Mohling mentions the role of the microbiome in estrogen metabolism (recycling and resorption of estrogen) and its impact on endometriosis.

  • Kirk Hamilton and Dr. Mohling discuss the potential benefits of fasting and dietary interventions like the fasting-mimicking diet.

Challenges and Controversies in Endometriosis Treatment…

  • Dr. Mohling discusses the limitations of hormonal treatments like birth control pills and hormone blockers.

  • She highlights the importance of excising endometriotic lesions to manage pain and improve quality of life.

  • Dr. Mohling shares her experience with patients who have been misdiagnosed or undertreated for endometriosis.

  • Kirk Hamilton and Dr. Mohling discuss the role of physical therapists in referring patients with pelvic pain to specialists.

Future Research and Personal Insights…

  • Dr. Mohling mentions her ongoing work on a book that bridges the concepts of surgical management and lifestyle changes for endometriosis.

  • She discusses the potential impact of COVID-19 on endometriosis symptoms but notes the lack of definitive evidence.

  • Dr. Mohling reflects on the evolution of endometriosis treatment and the importance of early diagnosis and comprehensive care.

  • Kirk Hamilton and Dr. Mohling conclude the interview with mutual appreciation for their shared commitment to integrative and lifestyle medicine.

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    Highlights…

SSRIS – ANTIANXIETY MEDICATIONS – SIDE EFFECTS – SSRIs and School Shootings, FDA Corruption, and Why Everyone on Anti-Depressants Is Totally Unhappy. Aug 29, 2025 The Tucker Carlson Show Interview with former FDA Medical Officer, Psychiatrist Josef Witt-Doerring, Medical Director of TaperClinic
Aug 29, 2025 The Tucker Carlson Show Aug 29, 2025 The Tucker Carlson Show
Chapters:
0:00 How Widespread Are Anti-Depressants?
11:03 The “Chemical Imbalance” Lie
15:03 Why Is Depression Rising?
22:36 The Dark Truth Dr. Witt-Doerring Uncovered While Studying Psychiatry
29:05 The Corruption of the FDA
39:32 The Untold Side Effects of SSRIs
54:30 The Testimonies of People Impacted by These Side Effects
103:45 Is There a Link Between SSRIs and Mass Shootings?
1:09:15 Horrifying Withdrawal Effects You Should Be Aware Of
1:20:32 What Is ADHD?
1:25:10 The Truth About Cannabis
1:30:05 How Dr. Witt-Doerring Helps People Get Off SSRIs
1:35:18 How Do SSRIs Impact Relationships?
1:40:46 The Telehealth Scam Taking Over the Country
1:44:13 The Scary New Law Pushing Drugs on Children
1:47:09 Dr. Witt-Doerring’s Advice to Someone Suffering From Depression
1:51:00 Why the Establishment Thinks Dr. Witt-Doerring Is Dangerous

SSRIS – VIOLENT CRIME – Two Massive Studies Show SSRIs Increase Homicidal Behavior & Violent Crime. As autistic transgender school shooters multiply, RFK Jr. is probing whether SSRIs — used by ~40% of trans individuals — are fueling the bloodshed. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse) Aug 29, 2025.
1) Antidepressant prescribing in transgender and nonbinary individuals diagnosed with gender dysphoria and mood or anxiety disorders.
2) Associations between selective serotonin reuptake inhibitors and violent crime in adolescents, young, and older adults – a Swedish register-based study.
3) Selective Serotonin Reuptake Inhibitors and Violent Crime: A Cohort Study.
4) Antidepressant prescribing in transgender and nonbinary individuals diagnosed with gender dysphoria and mood or anxiety disorders.
5) A comparison of gender diversity in transgender young people with and without autistic traits from the Trans 20 cohort study.
6) Long-Term Follow-Up of Transsexual Persons Undergoing Sex Reassignment Surgery: Cohort Study in Sweden.

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Nutrition, Prevention and Integrative Medicine…

ANTI-AGING – This Critical Amino Acid May Increase Life Expectancy, Early Research Suggests, By Francesca Bond, MindBodyGreen. August 23, 2025.
1) The potential protective effects of taurine on coronary heart disease.
2) Effects and Mechanisms of Taurine as a Therapeutic Agent.
3) Taurine deficiency as a driver of aging.

COVID 19 INFECTION – LOW OXYGEN LEVELS – IVERMECTIN – Dr.Sabine Hazan’s Experience with Ivermectin. Dr. William Makis MD, Covid Intel, Aug 27, 2025.

HEART FUNCTION – A Quiet Medicine: How Silence Slows Down Your Heart and Grows Neurons. The absence of sound speaks volumes.
1) Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non‐musicians: the importance of silence.
2) Acute and chronic endocrine effects of noise. Review of the research conducted at the Institute for water, soil and air hygiene.
3) Cardiovascular effects of environmental noise exposure.
4) Noise burden and the risk of myocardial infarction.
5) Speech is special: The stress effects of speech, noise, and silence during tasks requiring concentration.
6) The search for inner silence as a source for Eudemonia.
7) A default mode of brain function.
8) Resting in peace or noise: Scanner background noise suppresses default‐mode network.
9) What can the organization of the brain’s default mode network tell us about self-knowledge?
10)Correlates of Silence: Enhanced Microstructural Changes in the Uncinate Fasciculus.
11) Silence is golden: Extended silence, deliberative mindset, and value creation in negotiation.
12) Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non-musicians: the importance of silence.

VACCINATION – CHILDHOOD- TRUST – Childhood Vaccines: Who Can Parents Trust? Alex Lace Frustrated with Pediatricians and the Bio-Pharmaceutical Complex Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Aug 26, 2025.
1) RESOLUTION 2000-1: AAPS Resolution on Mandatory Vaccines.

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Cancer…

BREAST CANCER – IVERMECTIN and FENBENDAZOLE Testimonial – Virginia woman with 8cm Breast Cancer, poorly differentiated, has no chemo side effects! Dr. William Makis MD, Covid Intel, Aug 26, 2025.

CANCER – COVID -19 VACCINATION – First Population-Wide Study Finds COVID-19 “Vaccines” Increase Risk of Multiple Cancers. Official government data from nearly 300,000 people tracked for 30 months show mRNA shots significantly increase the risk of overall cancer, breast cancer, bladder cancer, and colorectal cancer. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Aug 30, 2025.
1) COVID-19 vaccination, all-cause mortality, and hospitalization for cancer: 30-month cohort study in an Italian province.

CANCER – COVID 19 VACCINATION – 17 Ways mRNA Shots May Cause Cancer, According to Over 100 Studies. Comprehensive literature review reveals how mRNA injections may induce, accelerate, or reactivate cancer through 17 distinct pathways. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Jun 24, 2025.
1) “COVID-19 mRNA vaccines can induce cancer in 17 distinct ways, according to over 100 studies”

COLON CANCER – IVERMECTIN and FENBENDAZOLE Testimonial – 51 year old UK man with Stage 4 Colon Cancer metastatic to peritoneum has amazing results after 2.5 months. Dr. William Makis MD, Covid Intel, Aug 28, 2025.

COLON CANCER -IVERMECTIN and MEBENDAZOLE Testimonial – 39 year old Texas woman with Stage 4 Colon Cancer metastatic to liver has amazing results after 4 months! Dr. William Makis MD, Covid Intel, Aug 28, 2025.

PANCREATIC CANCER – IVERMECTIN and FENBENDAZOLE Testimonial – 64 year old Ontario man with Stage 4 Pancreatic Cancer to liver has incredible response after 2 months, CA19-9 down 93%. Dr. William Makis MD, Covid Intel, Aug 28, 2025.

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Covid Syndrome…

COVID VACCINATION – AUTOIMMUNITY – Long-term risk of autoimmune diseases after mRNA-based SARS-CoV2 vaccination in a Korean, nationwide, population-based cohort study. “…We report that the risk of developing most AI-CTDs did not increase following mRNA vaccination, except for systemic lupus erythematosus with a 1.16-fold risk in vaccinated individuals relative to controls… However, a booster vaccination was associated with an increased risk of some AI-CTDs including alopecia areata, psoriasis, and rheumatoid arthritis. Overall, we conclude that mRNA-based vaccinations are not associated with an increased risk of most AI-CTDs, although further research is needed regarding its potential association with certain conditions…”

COVID 19 VACCINATION – Trump’s Reversal on Warp Speed Opens a Window of Opportunity to Halt COVID-19 mRNA Injections. Epidemiologist Nicolas Hulscher on Patriot. TV with JD Rucker. Nicolas Hulscher, MPH. Focal Point (Courageous Discourse) Sep 01, 2025.

COVID 19 VACCINATION – BREAKING: Trump Turns on Operation Warp Speed — Demands Big Pharma Release Hidden “Extraordinary” COVID Shot Data. TRUMP: “I hope OPERATION WARP SPEED was as ‘BRILLIANT’ as many say it was. If not, we all want to know about it, and why???”, Focal Points (Courageous Discourse), Nicolas Hulscher, MPH, Sep 01, 2025.

COVID VACCINATION – MAGNETISM – METALLIC COMPOUNDS – Clinical Manifestations of Iatrogenic Magnetism in Subjects After Receiving COVID-19 Injectables: Case Report Series. “…Redistribution of iron into the brain or other body parts may be causing iatrogenic magnetism…”

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Societal and World Health…

PARENTAL RIGHTS – HEALTHCARE BILL OF RIGHTS – IMA Launches Parents’ “Back to School” Healthcare Bill of Rights. The Independent Medical Alliance has launched a Parents’ Healthcare Bill of Rights just in time for back-to-school, restoring parental authority over kids’ health and education. Independent Medical Alliance, Aug 26, 2025.

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Did The COVID-19 vaccine Increase Mortality From April, 21 to May, 2023 In England?

An Interview With Jarle Aarstad, PhD

Jarle Aarstad, PhD
Western Norway University of Applied Sciences
Bergen, Norway
jarle.aarstad@hvl.no
(8/2025)

“Mortality involving and not involving COVID-19 among vaccinated vs. unvaccinated in England between Apr 21 and May 23.” F1000Research 2025, 14:133. (article accessed here) PDF Abstract
Kirk Hamilton PAC’s YouTube Commentary 9:16 sec:min

Previously titled: “The temporal protection and declining health of the COVID-19 vaccinated in England: A 26-month comparison of the mortality involving and not involving COVID-19 among vaccinated vs. unvaccinated.”

Kirk Hamilton: Can you please share with me your educational background and current position?

Jarle Aarstad: I am an economist with a PhD in business administration from the NHH Norwegian School of Economics. Now I am a full professor at Western Norway University of Applied Sciences, formally in innovation and entrepreneurship, with numerous publications, including in leading journals. Mostly, I use quantitative methodologies. Over the past few years, my research focus has shifted towards topics related to COVID-19 and vaccination, utilizing similar quantitative approaches.

KH: What got you interested in studying the mortality difference between the Covid vaccinated and non-vaccinated during the time period of April 2021 to May 2023?

JA: I had conducted country-level studies on vaccination and excess mortality, and I was interested in examining whether person-level data publicly available aligned with my previous research findings. Apr 21 to May 23 is the whole period for which the data are publicly available. If the period were extended, of course, I would include them in my study – the more data, the better. Having said that, the period available gives a fairly good insight into what happened in the aftermath of the vaccine rollout.

KH: Can you tell us about your study and the basic results?

JA: The study compared monthly mortality rates among vaccinated and unvaccinated individuals aged 10 years and older in England during the specified period. In my study, vaccinated individuals were those who had received at least one dose. The data provided is age-standardized, meaning that different age distributions among vaccinated and unvaccinated individuals are accounted for. However, observing differences in mortality may nonetheless be attributed to vaccine hesitancy, which raises concerns. That is, those not taking the vaccine may likely have inferior health at the outset, which can complicate isolating a genuine vaccine effect. To address the issue, I decided to compare all-cause mortality and mortality excluding COVID-19. (access article and figures here) Figure 1A particularly at the beginning of the period shows relatively high mortality among unvaccinated, but as the pattern is similar in Figure 1B concerning mortality not involving COVID-19, a large chunk of the difference can be attributed to unvaccinated having inferior health at the outside (the basic argument in that the vaccine cannot prevent mortality not involving COVID-19). Having said that, comparing the results from those figures, Figure 2A shows that the all-cause mortality, i.e., mortality including COVID-19 (between unvaccinated vs. vaccinated) was higher than mortality not involving COVID-19 (between unvaccinated vs. vaccinated) between July 21 and Jan 22 (the green vs. the orange plot). Having said that, there is a steady decrease in mortality among the unvaccinated compared to the vaccinated (best illustrated in Figure 3), or in other words, a steady increase in mortality among the vaccinated compared to the unvaccinated. I cannot find another explanation than the vaccine inducing a long-term increase in mortality. Together, the vaccines may have limited the relative increase in mortality among vaccinated individuals for a short period, but the overall trend points in a negative direction.

KH: Did you expect to see a reduction in mortality from Covid initially in the Covid vaccinated group?

JA: According to other research, which claims a temporal protective effect, yes. Nation-level analyses I have done show similar trends during the same period (but I have started doubting my previous conclusions, which is a topic for a study I am currently working on).

KH: Can you explain why difference in mortality might have not been do to the Covid vaccine protection but the poorer initial health of the non-vaccinated?

JA: As Figure 1B excludes mortality related to COVID-19, the only reason for the difference, particularly at the beginning of the period, in my opinion, is that unvaccinated individuals initially had poorer health. That we also know from other research. In Norway, 30% lower mortality among young vaccinated compared to unvaccinated people cannot be attributed to the vaccine since practically zero young people have died from COVID-19 here.

KH: When did you notice those vaccinated started having an increase in overall mortality from all causes?

JA: In Figure 3, you can observe that it increased among vaccinated individuals from the beginning of the period and decreased among unvaccinated individuals (possibly before, but I don’t have data). On the conservative end, the first months may have been outliers, but the overall trend is nonetheless as reported.

KH: How do your findings reflect on the overall mortality increase in those who took the Covid vaccine? Is the vaccine the probably causative agent?

JA: The vaccine is probably the causative agent, or at least, I cannot find other plausible explanations for the trends observed in Figs. 2A and 3 (the rollout may theoretically explain it, but I have discussed that). As the period followed an earlier period of excess mortality, one would expect a decrease in mortality; however, this is only observed among the unvaccinated.

KH: If this observation is correct of increased overall mortality in those vaccinated with limited benefit of the vaccine it sounds like the Covid vaccine is something that should not be implemented?

JA: I agree with you. The vaccine has caused substantial harm, with very few, if any, benefits.

KH: Do you have any idea of the causative agent (s) in the Covid vaccine that may be causing an increase in overall mortality (i.e. altered spike protein delivered via lipid nanoparticles being produced for an in-determinant amount of time causing inflammation to vascular, neuronal, reproductive and oncogenic susceptible tissues, or viral contaminants, etc.)

JA: As an economist, an expert in numbers but not specifically in medical issues, I leave that issue to other experts.

KH: Do we know how long the spike protein remains in the body?

JA: Again, I leave that for other experts.

KH: How would you further study this topic to corroborate your concerning findings.

JA: I have studied international data (from 39 countries with more than one billion people) that I have followed over three years, from 2021 to 2023, as well as US county data (with over 2000 observations) that I have also followed over the same period. Additionally, I conducted a study on young people in England, which revealed a significant increase in deaths in the weeks following vaccination. The pattern was similar for each dose.

KH: Thank you for your time and excellent science and courage to publish these findings. I look forward to sharing your future studies on this critically important subject.

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Highlights…

CANCER – BREAST – MELANOMA – PROSTATE CANCER – FENBENDAZOLE – Fenbendazole Linked to Remission or Near-Remission in Three Stage IV Cancer Patients.
1) A REVIEW OF IVERMECTIN USE IN CANCER PATIENTS: IS IT TIME TO REPURPOSE IVERMECTIN IN CANCER TREATMENT?
2) BREAST – PROSTATE MELANOMA – Fenbendazole as an Anticancer Agent? A Case Series of Self-Administration in Three Patients.

CANCER – POST-VACCINE – MECHANISM – New Study Defines Mechanisms of Post-Vaccine “Turbo Cancer” Peer-reviewed research from Drs. Paul Marik and Justus Hope links COVID-19 mRNA vaccines to “turbo cancer,” detailing five biological pathways that may drive aggressive, fast-growing cancers — Peer-reviewed research from Drs. Paul Marik and Justus Hope links COVID-19 mRNA vaccines to “turbo cancer,” detailing five biological pathways that may drive aggressive, fast-growing cancers — Independent Medical Alliance and Justus R. Hope, Aug 12, 2025. COVID-19 mRNA-Induced “Turbo Cancers” Abstract

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Nutrition, Prevention and Integrative Medicine…

AGING – WALKING – CADENCE – Walking cadence as a measure of activity intensity and impact on functional capacity for prefrail and frail older adults. PDF “…An increase of 14 steps/minute from their comfortable walking cadence increased the odds of improvement in 6-minute walk test minimum clinically important difference…”

ALZHEIMER’S DISEASE – BIOMARKERS – MUSCLE STRENGTH – Blood biomarkers of Alzheimer’s disease and 12-year muscle strength trajectories in community-dwelling older adults: a cohort study. “…Our findings suggest that blood Alzheimer’s disease-related biomarkers might help estimate progressive muscle strength decline among older adults, elucidating the influence of brain pathology and cognitive ageing on this association. These Alzheimer’s disease-related biomarkers could aid in identifying individuals for early intervention to prevent sarcopenia…”

ALZHEIMER’S DISEASE CHOLESTEROL SHOCKING: The TRUTH About Cholesterol and Alzheimer’s Goes VIRAL. “People with high cholesterol levels don’t get Alzheimer’s“,Died Suddenly News, Aug 19, 2025.

ALZHEIMER’S DISEASE – COGNITION – TESTING – Discover the Power of the p-Tau 217 Blood Test.

BENIGN PROSTATIC HYPERTROPHY – SHOCK WAVE THERAPY – Radial Extracorporeal Shock Wave Therapy as a Novel Agent for Benign Prostatic Hyperplasia Refractory to Current Medical Therapy. “…Each participant was treated with rESWT once a week for 8 weeks, each by 2000 impulses at 2.0 bar and 10 hertz of frequency…Statistically significant clinical improvements were reported for IPSS, QoL, and IIEF-5 after treatment, and those were sustained until 3 months follow-up. Qmax and PVR improved evidently at 8 weeks with a 63% and 70% improvement, respectively…”
1) A randomized controlled trial evaluating low-intensity shockwave therapy for treatment of persistent storage symptoms following transurethral surgery for benign prostatic obstruction.

BIOIDENTICAL HORMONE DEBATE – DR. KELLY VICTORY VS. DR. NAOMI WOLFE – NATIONAL PREPAREDNESS EXPERT. Disaster manipulation by public health officials.

BRAIN DEVELOPMENT – NEURODEVELOPMENT – INFANTS – EMFS – High Wireless EMF Exposure More Than Triples Risk of Neurodevelopmental Delays in Infants. First-ever infant cohort study using direct home RF-EMF measurements finds major increases in motor, problem-solving, and social deficits — even at everyday Wi-Fi and cell tower levels. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Aug 15, 2025.
1) Radio frequency Electromagnetic Field Emissions and Neurodevelopmental Outcomes in Infants: A Prospective Cohort Study. PDF

BRAIN EATING AMOEMBA – 12 year-old dies from a brain-eating amoeba. Could this happen to you? The chance of this happening to you is remote. Here’s how to make it even more remote. Film Primetime Steve KirsSteve Kirsch’s newsletterch, August 17, 2025.

COGNITION – BICYCLING – Want To Protect Your Brain As You Age? Research Says To Start Pedaling, By Ava Durgin, MindBodyGreen, July 28, 2025.
1) Active Travel Mode and Incident Dementia and Brain Structure.

COGNITION – PHYSICAL ACTIVITY – IMPROVEMENT – Associations of accelerometer-measured physical activity, sedentary behaviour, and sleep with next-day cognitive performance in older adults: a micro-longitudinal study. (MVPA – moderate-to-vigorous physical activity) “…Conclusions: Memory benefits of MVPA may persist for 24 h; longer sleep duration, particularly more time spent in SWS (slow wave sleep), could independently contribute to these benefits…”

DEMENTIA RISK REDUCTION – SLEEP – EXERCISE – FIBER- SUGAR REDUCTION
1) Cognitive Health Benefits of Everyday Physical Activity in a Diverse Sample of Middle-Aged Adults.
2) The Neuroprotective Aspects of Sleep.
3) Sleep disruption induces activation of inflammation and heightens risk for infectious disease: Role of impairments in thermoregulation and elevated ambient temperature.
4) Dietary sugar intake, genetic susceptibility, and risk of dementia: A prospective cohort study. “…both non-free sugar and free sugar intake are risk factors for the incidence of dementia, suggesting that intake of non-free sugars should also be limited…”
5) Alcohol and Dementia – What is the Link? A Systematic Review. (…High-level alcohol consumption (>14 drink units/week) is certainly linked to an increase in dementia risk, post-mortem reduction in brain volume and MRI signs of brain damage via possibly multiple pathways…”
6) Vitamin D and the risk of dementia and Alzheimer disease. “…Our results confirm that vitamin D deficiency is associated with a substantially increased risk of all-cause dementia and Alzheimer disease…”

DEPRESSION – What to Do About SSRI Withdrawal Mitochondrial Dysfunction. The tenth and final installment in our series on understanding the truth about SSRIs. Chris Masterjohn, PhD, Harnessing The Power of Nutrients, Aug 15, 2025.

HEART RATE VARIABILITY – WATERMELON – The Effect of Watermelon Juice Supplementation on Heart Rate Variability and Metabolic Response during an Oral Glucose Challenge: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial. PDF

MALARIA – CURE – RED CROSS – The Red Cross Suppressed A Cure For Malaria in 2012, Causing Over Half A Million People To Die Every Year Since. More evidence that international health care organizations (and all governmental health care and regulatory agencies) are fully captured by Big Pharma. Pierre Kory, MD, MPA, Pierre Kory’s Medical Musing, Aug 17, 2025.

PROSTATE CANCER - ONCOLOGIST - PREVENTIVE ADVICE - I’m an Oncologist–Here’s How I Protect Myself From Prostate Cancer. If illness strikes, your ability to get through treatment and recover depends on the resilience you’ve already built. By Dr. Manuj Agarwal, M.D., EPOCH Times, 8/12/2025.
1) Dietary intake of tomato and lycopene, blood levels of lycopene, and risk of total and specific cancers in adults: a systematic review and dose–response meta-analysis of prospective cohort studies.
2) Complementary and Alternative Medicine for Advanced Prostate Cancer.
3) Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications.
4) More evidence that physical activity is beneficial for prostate cancer.
5) Shifting the paradigm of testosterone and prostate cancer: the saturation model and the limits of androgen-dependent growth.
6) Role of zinc homeostasis in the prevention of prostate diseases.
7) Serum Insulin, Glucose, Indices of Insulin Resistance, and Risk of Prostate Cancer.
8) Chronic Stress Promotes Cancer Development.
9) Chronotype, sleep timing, sleep regularity, and cancer risk: A systematic review.
10) Endocrine disruptors and prostate cancer risk.
11) Selenium and Vitamin E Cancer Prevention Trial (SELECT): Questions and Answers.
12) Association Between Red and Processed Meat Consumption and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis.
13) Prostate Cancer Risk Factors.

VACCINATION – CDC Sued for Pushing Illegal 72-Dose Childhood Vaccine Schedule. CDC accused of running an illegal and unconstitutional hyper-vaccination program — never once tested for cumulative safety. Nicolas Hulscher, MPH. Focal Points (Courageous Discourse, Aug 18, 2025.

VACCINATION – HEALTH AND HUMAN SERVICES – HEALTH CANADA – The Vaccine Cartel Strikes Back. American Academy of Pediatrics pushes mRNA shots for babies against HHS guidance — as Health Canada approves Pfizer’s LP.8.1 mRNA injection for infants. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Aug 19, 2025.

VACCINATION – EXEMPTIONS – INCREASING – Vaccination Coverage and Exemptions among Kindergartners. Report from CDC Indicates Increasing Numbers of Parents Filing Exemptions. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Aug 18, 2025.
1) Vaccination Coverage and Exemptions among Kindergartners, July 31, 2025.

VACCINATION – FLU – COVID STROKE – U.S Government Researchers Warn of Elevated Stroke Risk After Covid and Flu ‘Vaccine’ Co-Administration Dr. William Makis MD, Aug 21, 2025.
1) A Three-Part Model for the Self-Controlled Case Series Design to Estimate and Characterize, Adverse Event Risk in an Overlapping Risk Period after Multiple Vaccines: Application to Ischemic Stroke Following Pfizer-BioNTech Bivalent COVID-19 Vaccine and Influenza Vaccine.
1) Effectiveness of the Influenza Vaccine During the 2024-2025 Respiratory Viral Season. (Conclusion: Influenza vaccine in-effective )

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for the full content of this SUBSTACK’S POST
on “Cancer and covid syndrome” CLICK HERE

_____________________________________________________________________________

Societal and World Health…

FORCED ORGAN HARVESTING – REWARDS – CONGRESS – CCP’s New Push to Eliminate Falun Gong and Shen Yun Globally.
1) Congressmen Urge State Department to Combat China’s Forced Organ Harvesting with Rewards for Information – Letter to Secretary of State Marco Rubio.

PANAMA CANAL – CHINA BRIDGE CONSTRUCTION – Panama Canal 13 August 2025 — China Continues to Build Bridge. Big Regional Fight Unfolding. Michael Yon, Michael’s Newsletter, August 13, 2025. Another Chinese Bridged Collapses……while China Builds Another Bridge over PANAMA CANAL, Michael Yon, Michael’s Newsletter, Aug 24, 2025.

_____________________________________________________________________________

Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Intergenerational Day Centers: A New Wave in Adult & Child Day Care: An Interview with Dr. Neda Norouzi, PhD

From Loving Great Grandparents and Memories, to Working in Daycare, to Studying Architecture Helping Answer a Need for Taking Care of the Elderly and Children and Benefiting Both in the Process... (Video Interview)

Intergenerational Day Centers: A New Wave in Adult and Child Day Care
and Interview with Dr. Neda Norouzi, PhD

Neda Norouzi, PhD, M.Arch, MURP, B.Env.D
School of Architecture + Planning
The University of Texas at San Antonio
San Antonio, TX 78703, neda.norouzi@utsa.edu

“Intergenerational Day Centers: A New Wave in Adult and Child Day Care. Int J Environ Res Public Health. 2023 Jan 1;20(1):809. Abstract

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Kirk’s Comments: I was first intrigued by this article by the possible positive health aspect for both age groups but, especially the elderly interacting together. From reading about Blue Zone cultures to my own experiences with my grand children being around youth and young life can keep you thinking and acting younger and challenging you in life giving ways.

Then after reading about Dr. Norouzi’s background as an architect and education in urban planning I thought do we really want municipalities and local governments to fund and implement such facilities. I have concerns about governmental waste and bureaucracy and the safety concerns of the young children around adults. I ask about them in the interview.

If I was going to have a person try and put together such a facility and program in a private business or municipal setting Dr. Neda Norouzi checks all the “positive” boxes of someone who could do this with multidimensional expertise.

First her love of family and her “great” grandparent stories and love of children let you know right off how she values family. After she immigrated to this country she worked in daycare for years. Then she has all the academic credentials for urban planning and architecture. And because of her passion for the topic she is the perfect person to oversea such an endeavor. A very interesting topic. I hope you enjoy our conversation.

Kirk

(Otter.Ai Generated Summary of Interview Transcript)

Intergenerational Day Centers: Introduction and Guest Background

  • Kirk Hamilton introduces the topic of intergenerational day centers and his guest, Dr. Neda Norouzi, a PhD from the University of Texas at San Antonio.

  • Dr. Norouzi shares her educational background, starting from her birth in Iran, her move to the U.S., and her initial job at a daycare center.

  • She discusses her transition from child development courses to studying architecture and urban planning, influenced by her interest in solving public problems.

  • Dr. Norouzi explains her master's thesis on intergenerational programs, inspired by her personal experiences with her great-grandparents.

Personal Experiences and Research Journey

  • Dr. Norouzi recounts her experiences with her great-grandparents in Iran, which influenced her interest in intergenerational design.

  • She describes her master's thesis on intergenerational programs and how it led to her job in DC and further research.

  • Dr. Norouzi shares her journey to obtaining a PhD in architecture, focusing on intergenerational design, and her involvement with Generations United.

  • She highlights the importance of understanding the client-designer relationship and the impact of her research on designing for intergenerational centers.

Benefits of Intergenerational Programs

  • Kirk Hamilton and Dr. Norouzi discuss the benefits of intergenerational programs for both the elderly and children.

  • Dr. Norouzi emphasizes the energy and physical activity that older adults experience when interacting with children.

  • She notes the cognitive benefits for older adults, such as improved memory and cognitive functions.

  • For children, Dr. Norouzi highlights the love and unconditional support they receive from older adults, as well as the academic and social-emotional skills they develop.

Designing Intergenerational Centers

  • Dr. Norouzi explains the importance of designing intergenerational centers that facilitate organic interactions between children and older adults.

  • She discusses the challenges of integrating intergenerational activities into existing facilities and the need for dedicated spaces.

  • Dr. Norouzi shares examples of successful intergenerational centers and the types of activities that are conducted.

  • She emphasizes the need for flexible designs that allow for different levels of interaction and the importance of supervision to ensure safety.

Challenges and Future of Intergenerational Centers

  • Dr. Norouzi addresses the challenges of implementing intergenerational centers, including the need for city involvement and funding.

  • She discusses the potential for private businesses to see the benefits of intergenerational centers and invest in them.

  • Dr. Norouzi shares her vision of having intergenerational centers become a common feature in every city.

  • She reflects on the importance of these centers in a society where families are often geographically dispersed, providing non-familial interactions that foster understanding and connection between generations.
    _______________________________________________________________________

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Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

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___________________________________________________________________________

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

What is the Evidence and Possible Mechanisms of How Meditation Can Change Our Biology and Health?

Hemal H. Patel, PhD
Professor & Vice-Chair for Development and Advancement
Director, UCSD Cardiac/Neuro Protection Laboratories
VA Research Career Scientist, VA San Diego Healthcare System
Video Interview
Department of Anesthesiology, University of California, San Diego
Biomedical Sciences Building, Mail Code 0629, 9500 Gilman Drive
La Jolla, CA 92093-0629. e-mail: hepatel@ucsd.edu (08/13/25)

Meditation-induced bloodborne factors as an adjuvant treatment to COVID-19 disease. Brain Behav Immun Health. 2023 Aug 7;32:100675. PDF

Key Findings…

  • Length of meditation practice may influence susceptibility and management of COVID-19.

  • Blood plasma from mediators can limit viral infection in cultured lung cells.

  • Meditation elevates SERPINA5, a major player in coagulation and the immune response.

  • Regular meditation practice can improve well-being by modulation of biological processes.

“Multidimensional Analysis of Twin Sets During an Intensive Week-Long Meditation Retreat: A Pilot Study,” Mindfulness (N Y). 2025;16(6):1634-1655. PDF

Key Findings…

  • Meditation may increase a family of proteins called “plasmalogens” that act as antioxidants – which protect us from a number of chronic diseases and have an anti-aging effect.

  • Meditation may increase tryptophan metabolism. This leads to the production of serotonin – a vital mood regulator; and melatonin – a hormone that regulates the sleep-wake cycle.

  • Meditation may elevate proteins in the blood that lead to tissue repair and regeneration.
    _________________________________________________________________________

    (Otter.Ai Generated Summary of Partial Transcript)

    Initial Research Findings and Personal Experiences

    Dr. Patel shares his initial skepticism and eventual participation in meditation events, which led to significant personal and professional insights.

    He describes the unique research environment at meditation events, where participants are controlled for various factors, making it easier to study biological changes.

    Dr. Patel highlights the dramatic biochemical shifts observed in novice meditators compared to experienced meditators and controls.

    He discusses the potential for meditation to impact a wide range of diseases, drawing parallels to the development of pharmaceutical drugs for specific diseases.

    Biological Measurements and Data Collection

    Dr. Patel explains the comprehensive data collection at meditation events, including wearable devices, blood samples, saliva, and stress markers.

    He describes the use of video diaries to capture participants' facial expressions and speech, which can be analyzed for changes in biology.

    Dr. Patel discusses the goal of providing biofeedback to participants, allowing them to monitor their meditation practices and health.

    He highlights the unexpected prevalence of mental health and other diseases among meditation event participants, suggesting a broader impact of meditation on health.

    Meditation and Biological Changes

    Dr. Patel elaborates on the biological changes observed in meditation participants, including shifts in the microbiome, heart rate variability, and brainwave patterns.

    He describes the concept of the "human collectome," encompassing all measurable biological factors in an individual.

    Dr. Patel discusses the potential for meditation to create a synergistic effect when combined with Western medical treatments, such as chemotherapy for cancer.

    He shares his personal approach to health, emphasizing the importance of combining various therapies and maintaining an open mind.

    Covid-19 Study and Meditation

    Dr. Patel explains the study on meditation-induced factors as an adjuvant treatment for COVID-19, which was conducted using pseudo viruses to simulate the SARS-CoV-2 virus.

    He describes the survey data showing that avid meditators had less severe COVID-19 symptoms and faster recovery times.

    Dr. Patel details the laboratory experiments showing that plasma from meditators inhibited the virus from entering cells, suggesting a protective effect.

    He identifies serpin A5 as a key protein elevated in meditators, which may contribute to this protective effect.

    Twin Study and Socialization Dynamics

    Dr. Patel discusses the twin study, which explored the socialization and connectedness of identical and fraternal twins during a week-long meditation retreat.

    He describes the methodology, including separating twins at specific times during the retreat to measure their individual and collective changes.

    Dr. Patel highlights the significant biological divergence observed in twins during the retreat, followed by a convergence at the end.

    He speculates on the potential for socialization and connectedness to influence biological changes, beyond genetic factors.

    Future Research and Conclusion

    Dr. Patel mentions ongoing studies on the effects of meditation on aging, involving pairs of individuals with a 30-year age difference.

    He discusses the potential for meditation to improve healthy aging and the importance of multi-generational interactions.

    Dr. Patel touches on the concept of distant healing, where groups focus on individuals remotely, and the preliminary data showing significant biological changes.

    He concludes by emphasizing the need for further research to validate these findings and explore the mechanisms behind meditation's health benefits.

    _________________________________________________________________________

Falun Dafa – Truthfulness, Compassion and Forbearance
Brief Introduction to Falun Dafa
Books & Recent Writings of Mr. Li Hongzhi
Video & Audio Materials
Take an Online Class

Share

_________________________________________________________________________

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Integrative Medicine Research for August 11, 2025

Nutrition, Prevention and Integrative Medicine…

AGING - FLAVONOL RICH FOODS - Associations between flavonoid-rich food and flavonoid intakes and incident unhealthy aging outcomes in older United States males and females. 10 Top Foods High in Flavonols (WebMed). Lettuce, Tomatoes, Onions, Kale, Apples, Grapes, Berries, Tea, Red wine.

AGING- SITTING - How Floor Sitting Can Improve Balance, Posture, and Longevity Americans often overlook floor sitting as an option that is associated with better joint mobility and balance that can reduce fall risk. By Amy Denney, EPOCH Times, 8/2/2025.
1) A systematic review of research on sitting and working furniture ergonomic from 2012 to 2022: Analysis of assessment approaches.
2) Postural and spinal stability analysis for different floor sitting styles.
3) The Biomechanical Effects of Cross-Legged Sitting on the Lower Limbs and the Implications in Rehabilitation.

BRAIN INJURY - CREATININE - Research Shows That Creatine May Protect The Brain From Injuries, By Molly Knudsen, M.S., RDN, MindBodyGreen, August 06, 2025.
1) Potential for use of creatine supplementation following mild traumatic brain injury.
2) Creatine supplementation enhances immunological function of neutrophils by increasing cellular adenosine triphosphate.
3) Creatine in Health and Disease.
4) Pilot study protocol of a randomized controlled trial for the potential effects of creatine monohydrate on persistent post-concussive symptoms.
5) Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials.
6) Effects of creatine on mental fatigue and cerebral hemoglobin oxygenation.

COGNITION - ARTIFICIAL INTELLIGENCE (AI) - Every prompt may be coming at the cost of cognitive efficiency and creativity. By Makai Allbert, EPOCH Times, 7/30/2025.
1) Your Brain on ChatGPT: Accumulation of Cognitive Debt when Using an
AI Assistant for Essay Writing Task.
2) Habitual use of GPS negatively impacts spatial memory during self-guided navigation.

COGNITION - SUGAR - How Your Brain’s Sugar Processing Could Influence Alzheimer’s Disease Risk. A recent study links poor sugar processing in the brain to memory loss–but fasting and certain treatments may offer protection. By George Citroner, EPOCH Times, 8/7/2025.
1) Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reduction.

DEPRESSION - SSRIS- SEROTINON REUPTAKE INHIBITORS - The Dark Side of SSRIs. The shocking truth about SSRIs: minimal efficacy, serious withdrawal, and a debunked serotonin theory. Author Laura Delano joins Dr. Varon and Dr. Marik to discuss her book "Unshrunk". Unshrunk: A Story of Psychiatric Treatment Resistance Hardcover. March 8, 2025. by Laura Delano (Author). Independent Medical Alliance, Aug 08, 2025.

PARKINSON’S DISEASE - IVERMECTIN and FENBENDAZOLE Testimonial - 78 year old Nebraska PARKINSON'S DISEASE patient of 8 years, cured after 4 months!Dr. William Makis MD, Covid Intel, Aug 07, 2025.

SUDDEN DEATH - HEART ATTACK - HALF MARATHON - 28 year old Rugby player collapsed and died during the Great Bristol Run Half Marathon on May 12, 2025. Dr. William Makis MD, Covid Intel, Jul 16, 2025.

SUDDEN DEATH - MYOCARDITIS - INFLUENZA VACCINE - Childhood Vaccine Injuries - 7 year old Kaylynne Matten died after Influenza Vaccine. Dr. William Makis MD, Covid Intel, Jul 17, 2025.

VACCINES - COVID 19 - RESPIRATORY INFECTIONS - HHS to Terminate 22 BARDA mRNA Shot Projects Worth $500M. FK JR: "The data show these vaccines fail to protect effectively against upper respiratory infections like COVID and flu." Focal Points/ Courageous Discourse, Nicolas Hulscher, MPH, Aug 05, 2025.

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Cancer…

BIOPSIES - CANCER SPREAD - Doctor Who Cured 92% Of Cancer Patients Says Biopsies Are SPREADING Cancer. A needle biopsy punctures the tumor and releases the toxins into the system. Died Suddenly News, Aug 09, 2025. Doctor Who Has Saved Thousands of Lives Says Tumors are Protective Mechanisms but Biopsies Release Cancer Cells and Kill You.
1) Needle track seeding in renal mass biopsies.

CANCER - STATISTICS - INCIDENCE - Annual Report to the Nation 2025: Overall Cancer Statistics. Registry Data Show Mixed Picture. Peter A. McCullough, MD, MPH, Focal Points/ Courageous Discourse, Aug 09, 2025.
1) Seers.cancer.gov

CHEMOTHERAPY - CANCER CELLS - Chemotherapy awakens dormant cancer cells in lung by inducing neutrophil extracellular traps. “…This study provides direct evidence of dormancy awakening and reveals a mechanism underlying detrimental effect of chemotherapy on metastasis, highlighting potential strategies to improve cancer treatment…”

GASTRIC CANCER - IVERMECTIN and MEBENDAZOLE Testimonial - 72 year old Dallas, Texas woman with Stage 4 Gastric Cancer outlives her Oncologist's life expectancy prediction. Dr. William Makis MD, Covid Intel, Aug 05, 2025.

OVARIAN CANCER - IVERMECTIN and MEBENDAZOLE Testimonial - 76 year old San Francisco woman with Stage 4 Mullerian Carcinoma (Ovarian) with brain metastases reports after 3 months. Dr. William Makis MD, Covid Intel, Aug 09, 2025.

SARCOMA - IVERMECTIN and MEBENDAZOLE Testimonial - 25 year old woman in Greece with Stage 4 Ewing Sarcoma metastatic to the lungs, sees positive results after 2 months. Dr. William Makis MD, Covid Intel, Aug 05, 2025.

Covid Syndrome…

COVID VACCINE - MORE COVID INFECTION - Eighth Study Confirms mRNA Shots Increase Infection Risk. New study of 1,745 healthcare workers finds mRNA boosters raise risk of influenza-like illness by up to 70% and increase workdays lost by 50%. Nicolas Hulscher, MPH, Focal Point/Courageous Discourse, Aug 10, 2025.
1) Association of SARS-CoV-2 vaccination status with risk of influenza-like illness and loss of workdays in healthcare workers.
2) Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine.
3) Protection From COVID-19 Vaccination and Prior SARS-CoV-2 Infection Among Children Aged 6 Months–4 Years, United States, September 2022–April 2023.
4) Post-vaccination IgG4 and IgG2 class switch associates with increased risk of SARS-CoV-2 infections.
5) Effectiveness of the 2023-to-2024 XBB.1.5 COVID-19 Vaccines Over Long-Term Follow-up: A Target Trial Emulation.
6) Behavioral and Health Outcomes of mRNA COVID-19 Vaccination: A Case-Control Study in Japanese Small and Medium-Sized Enterprises.
7) Rate of SARS-CoV-2 Reinfection During an Omicron Wave in Iceland.
8) Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar.
9) Effectiveness of the Coronavirus Disease 2019 Bivalent Vaccine.

COVID VACCINE - PUBLISHED STUDIES - The McCullough Foundation Has Published Over 20 Manuscripts Exposing the Dangers of COVID-19 mRNA Vaccination.Epidemiologist Nicholas Hulscher joins FNL Freedom News to discuss the McCullough Foundation’s vital research efforts — exposing mRNA harms and advancing solutions for the injured. Nicolas Hulscher, MPH, Focal Point/Courageous Discourse, Jul 16, 2025.

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Societal and World Health…

ENVIRONMENT - FOSSIL FUEL - Berkeley Professor Reveals That Drilling Oil in California Might Be Good for the Environment | James Rector, California Insider Show.

TRANSPLANT MEDICINE - ORGAN DONOR ABUSE - RFK Exposes 103 Cases of Organ Transplant Abuse. (YouTube) Prime Time, Epoch Times, Roman Balmakov,August 8, 20025.

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Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Colon Cancer and Vitamin D, Mechanisms In Prevention and Treatment: An Interview with Professor Glen Jeffery

Glen Jeffery, PhD, BSc
Professor of Neuroscience
Institute of Ophthalmology, University College London
11-43 Bath St, London EC1V9EL, UK
g.jeffery@ucl.ac.uk (08-07-25 )
video interview click here

“Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision. Sci Rep 15, 24435 (2025) Full Article & Abstract

[Below is a ChatGPT summary of the unedited transcript from the video above with the article abstract with ChatGPT instructed to summarize and improve the grammar of the interview. This abbreviated summary was approved by Dr. Glen Jeffery and Kirk Hamilton PAC]

Improved Vision, Mitochondrial Function, and the Potential Benefits of Long-Wavelength Red Light Therapy

An Interview with Professor Glen Jeffery, PhD, BSc
Professor of Neuroscience, Institute of Ophthalmology, University College London

Interviewed by Kirk Hamilton, PAC
Host, Staying Healthy Today Show
Recorded: August 7, 2025

KIRK HAMILTON:
Hi everyone, I’m Kirk Hamilton, your host of the Staying Healthy Today Show—where we explore the fields of nutrition, prevention, and integrative lifestyle medicine. Today, we're diving into a fascinating topic: how longer wavelengths of light, specifically red and infrared, can improve vision and mitochondrial function.

When I saw the title of Professor Glen Jeffery’s recent study, “Longer Wavelengths in Sunlight Pass Through the Human Body and Have a Systemic Impact Which Improves Vision,” I was immediately intrigued. As someone who loves sunlight and believes it's benefits are more than just vitamin D I was very interested in talking to him.

So, joining us from London is Professor Glen Jeffery, PhD, Professor of Neuroscience at the Institute of Ophthalmology at University College London. Dr. Jeffery, thank you so much for being here today.

GLEN JEFFERY:
Thank you, it’s a pleasure.

Why This Research?

KIRK HAMILTON:
Let’s start at the beginning. What inspired you to study red and infrared light, and what were you hoping to discover?

GLEN JEFFERY:
Great question. About 15 years ago, I started seeing consistent evidence in the scientific literature showing that long-wavelength light—particularly in the red and near-infrared spectrum—has beneficial effects on cellular metabolism, particularly in mitochondria.

I also wanted to translate our lab findings into real-world scenarios, which is often a missing step in science. So, we did something simple: we exposed people to sunlight and measured what wavelengths actually passed through their bodies. We found that infrared light from the sun does penetrate through the torso, and we measured it coming out the back. That surprised us—but physicists had predicted it.

Then, we recreated that sunlight exposure in the lab using specific LED wavelengths (830–860 nm) and tested how that affected vision and mitochondrial function. The results were consistent: infrared light exposure improved vision, even when the eyes themselves weren’t directly exposed.

How Light Affects Mitochondria—and Vision

KIRK HAMILTON:
So how exactly does this type of light improve vision and mitochondrial function?

GLEN JEFFERY:
Well, mitochondria are the energy factories of your cells. When you hit them with long-wavelength light, they produce more ATP, the energy currency of the cell. That supports improved cellular function across the board.

Now, the retina has more mitochondria per cell than almost any other tissue, so it’s an ideal place to see an effect. We used a simple visual test—colored letters on a noisy background—to measure color contrast sensitivity. It’s an easy metric, and we saw improvements within 24 hours of exposure.

Sunlight vs Red Light Therapy Devices

KIRK HAMILTON:
Was the light in your studies natural sunlight, or did you use red light therapy devices?

GLEN JEFFERY:
Both. Sunlight has enormous amounts of infrared light—more than any LED device can reproduce. In the study, we first tested people outside and measured which wavelengths passed through their bodies. Then we created a lab device mimicking those wavelengths and got the same positive results indoors.

Clothing doesn’t block the infrared light, by the way—it attenuates it slightly but still lets it through. So whether you're wearing a shirt or not, sunlight’s longer wavelengths can still reach your tissues.

Practical Applications: Just Go for a Walk

KIRK HAMILTON:
So, for the average person—is just getting outside for a walk is enough?

GLEN JEFFERY:
Absolutely! Keep your credit card in your pocket and go for a walk. You’ll get all the infrared light you need—free of charge—and it’s incredibly beneficial.

Even on cloudy days, there’s still plenty of scattered infrared light. Water in the clouds does scatter it, but it doesn’t eliminate it. There’s no excuse not to go outside.

Critical Care, Architecture, and Incandescent Bulbs

KIRK HAMILTON:
So how does this research apply in places like hospitals or care homes?

GLEN JEFFERY:
Hospitals and modern buildings are a problem. Most indoor lighting is LED-based, which contains zero long-wavelength infrared light. That’s why we’ve been working with critical care units in major London hospitals to introduce light sources that enrich the environment with infrared.

One of the best solutions? Old-fashioned incandescent bulbs. They produce a smooth spectrum of light, very similar to sunlight, including plenty of infrared. They’re cheap, effective, and much better than most “full-spectrum” LEDs.

Unfortunately, they're being phased out in both the US and UK for energy efficiency reasons. But from a health perspective—especially for mitochondrial function—incandescents are far superior.

Real-World Impacts: Grip Strength, Vision, Inflammation

KIRK HAMILTON:
Have you seen other measurable benefits besides vision?

GLEN JEFFERY:
Yes, other researchers in London have shown that grip strength improves with similar light exposure. That’s a big deal for aging populations. Better grip strength means improved motor function, fewer falls, and longer healthspan.

There’s also a fantastic study from a U.S. city where they planted thousands of trees and found that residents' CRP levels—an inflammation marker—went down. Trees reflect infrared light. So, just walking through greenery can shower you in therapeutic infrared.

On Aging, Vision, and Public Health

KIRK HAMILTON:
You mentioned earlier vision and aging. Can regular exposure to this light help prevent vision loss, like macular degeneration?

GLEN JEFFERY:
Yes, we’ve shown that older individuals experience improved color vision after red light exposure. I did a clinical trial for macular degeneration that didn’t succeed—likely due to patient selection—but another UK trial just finished and showed significant benefits in early-stage macular degeneration.

This kind of light could become a non-invasive therapy for age-related conditions where mitochondrial decline plays a central role.

Final Thoughts: Simple, Free, and Effective!

KIRK HAMILTON:
This has been incredibly eye-opening. Any final thoughts you'd like to share?

GLEN JEFFERY:
Sure. Let me say it again: Don’t spend your money. Just go for a walk. The cardiovascular benefits of walking are well known, but now we know it also recharges your cellular batteries—your mitochondria.

And to be clear, I have half a dozen expensive red light devices sitting in my office—sent to me by companies. Some of them have $15 worth of parts and sell for thousands. The science doesn’t require that. Just step outside.

KIRK HAMILTON:
That’s a great way to end. Go for a walk, recharge your mitochondria, and save your money. Thank you, Dr. Jeffery, for your time, your research, and for bringing this down to earth.

GLEN JEFFERY:
My pleasure, Kirk. Stay well.

Key Takeaways:

  • Infrared light (830–860 nm) from sunlight penetrates deeply through the body and boosts mitochondrial function.

  • This improves vision, grip strength, motor skills, and likely reduces inflammation.

  • Sunlight is more effective than most red light therapy devices—and it's free.

  • Even clothing doesn’t block therapeutic infrared light.

  • Modern lighting—especially LED—removes infrared, potentially impacting long-term health.

  • Incandescent bulbs offer a more natural light spectrum and may support better health indoors.

    Kirk’s Comments:

  • Dr. Jeffery and colleagues work confirms my own personal experience that feeling better in sunlight goes beyond vitamin D but could be the energy and well-being enhancement of improved mitochondrial function and ATP production (and vitamin D!).

  • How convenient that you can get a beneficial ATP boosting effect even with your clothes on and even on an overcast day and you are walking through trees! All you have to do is go outside and walk!

  • The designing of the new Mayo Clinic building on the east coast that will be mostly glass, and Dr. Jeffery’s discussion about patients being close to windows in the critical care units dong better, reminds me after my colon cancer surgery (colectomy). As I was walking in the hospital hallways and I would sit with my back up against the window and feel the warm of the sun coming through the window and how good that felt! Stimulating mitochondria I bet!

  • I think of how many conditions and patients could improve just by walking or exercising outside!

  • It was very intriguing that grip strength improved by those getting longer wavelengths of light.

  • And for those that have macular degeneration get out side and get exposed to full spectrum light.

  • It left with me a smile on my face with incandescent lights being potentially healing and how we have tried to do away with them. If I can I am going to get a few lamps with incandescent lights for my home.

  • When in doubt. Keep your wallet in your pocket and go for a walk even on a cloudy day or under trees. You will still get some benefit from full spectrum long wavelength healing light. Your ATP producing mitochondria with thank you…And you might also prevent a fall with improved grip strength.

FOR THIS ENTIRE “STAYING HEALTHY TODAY” POST CLICK HERE

FOR KIRK HAMILTON’S SUBSTACK “STAYING HEALTHY TODAY CLICK HERE

Kirk Hamilton PA-C
Health Associates Medical Group
3301 Alta Arden, Suite 3
Sacramento, CA 95825
(916) 489-4400 (w)
krhammer@surewest.net
StayingHealthyToday Substack
www.StayingHealthyToday.com
www.HealthyLivingforBusypeople.com
www.KwikerMedical.com

Research in Nutrition, Prevention, and Integrative Medicine: August 2, 2025

Nutrition, Prevention and Integrative Medicine…

AGING - DIET - BEANS - LEGUMES -5 Delicious Ways to Eat a Cup of Beans Each Day By Tim Cebula, Blue Zones News Letter, July 2025.
1) Savory Roasted Chickpeas
2) Sardinian Pasta Fagioli
3) One-Hour, Crowd-Feeding Chili
4) Red Beans And Rice
5) Lentil Gnocchi
6) Ikarian Longevity Stew With Black Eyed Peas
7) Okinawan Rice and Bean Sprouts
8) Black Bean Breakfast Burritos
9) Panchita’s Gallo Pinto
10)Miso Soup with Vegetables
11) Black Bean Chocolate Chunk Brownies
12) Bush Beans - Blue Zones

AGING - DIET - CARBOHYDRATES - WOMEN - The Truth About Carbs For Women’s Health, According To Science, By Ava Durgin, , MindBodyGreen, July 28, 2025.
1) Dietary Carbohydrate Intake, Carbohydrate Quality, and Healthy Aging in Women.

AGING - PRESCHOOL - INTERGENERATIONAL PROGRAMS - What Happens When You Integrate a Preschool into a Long-Term Care Facility? Joy and Purpose for All. By Aislinn Kotifani, Blue Zones Newsletter, 2025.
1) Multigenerational Living Is the New Rapidly Growing Trend.
2) Intergenerational programs: What can school-age children and older people expect from them? A systematic review.
3) MAKING THE CASE FOR INTERGENERATIONAL PROGRAMS.
4) Intergenerational Day Centers: A New Wave in Adult and Child.

ALZHEIMER’S DISEASE - EGG - Association of Egg Intake With Alzheimer’s Dementia Risk in Older Adults: The Rush Memory and Aging Project. (“…These findings suggest that frequent egg consumption is associated with a lower risk of Alzheimer’s dementia and AD pathology, and the association with Alzheimer’s dementia is partially mediated through dietary choline…”). Kirk’s Comment: Eggs are one of the more frequent allergens/food intolerances while on paper good nutritionally. If you eat them daily or 3-4 times per week take two weeks off and see if any annoying symptoms go away or come back upon reintroduction. Eggs also have been associated with Type 2 diabetes. Make sure you are trim and have an hemoglobin A1C 5.6 or less if you are an egg eater.

BLOOD PRESSURE - BEET JUICE - Ageing modifies the oral microbiome, nitric oxide bioavailability and vascular responses to dietary nitrate supplementation. “…Greater blood pressure benefits from supplemental dietary nitrate in older compared to younger people are mediated primarily by the suppression of potentially harmful oral bacteria, that have been associated with ammonia production…”

BRAIN VOLUME - MAGNESIUM - Dietary magnesium intake is related to larger brain volumes and lowerwhite matter lesions with notable sex differences.

CARDIOVASCULAR DISEASE - COCOA FLAVONOL - Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial.

CARDIOVASCULAR EVENT - Systematic Review Finds Devastating Cardiopulmonary Adverse Events after COVID-19 Vaccination. Thousands of Papers Identified Heart and Lung Damage, Biased AI Falsely Claims "Rare and Mild". Peter A. McCullough, MD, MPH, Focal Point/Courageous Discourse, Jul 29, 2025.

COGNITIVE FUNCTION - CARDIOVASCULAR DISEASE - Wild blueberry (poly)phenols can improve vascular function and cognitive performance in healthy older individuals: a double-blind randomized controlled trial.

COGNITION - SLEEP - This One Sleep Habit Might Matter More Than Hours Slept For Cognitive Health, By Ava Durgin, MindBodyGreen, July 25, 2025.
1)Lower slow wave sleep and rapid eye movement sleep are associated with brain atrophy of Alzheimer’s disease-vulnerable regions.
2) β-Amyloid accumulation in the human brain after one night of sleep deprivation.
3) The Dynamic Relationship between the Glymphatic System, Aging, Memory, and Sleep.
4) The effect of caffeine on subsequent sleep: A systematic review and meta-analysis.
5)Exercise improves the quality of slow-wave sleep by increasing slow-wave stability.
6) The effect of alcohol on subsequent sleep in healthy adults: A systematic review and meta-analysis.

COLORECTAL CANCER - VITAMIN D - Vitamin D’s Potential Role in Colorectal Cancer Prevention, Immune Health.

COLORECTAL CANCER - VITAMIN D - Vitamin D and Colorectal Cancer Prevention: Immunological. “…Maintaining optimal vitamin D levels and adequate dietary intake is crucial in preventing CRC and improving patient prognosis…”

DEMENTIA - IVERMECTIN Testimonial in Dementia - 92 year old mother in Japan has incredible response to low dose Ivermectin in her last months. Dr. William Makis MD, Covid Intel, Aug 01, 2025.

DEPRESSION - MAGNESIUM - Magnesium Depletion Linked to Depression and How to Replenish It Effectively. Personalized nutrition strategies offer new hope for low magnesium and mood disorders. By Zena le Roux, EPOCH Times, 7/28/2025.
1) Magnesium depletion score and depression: a positive correlation among US adults.
2) Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose–Response Meta-analysis of Epidemiologic Studies.

DIABETES RISK - SUGAR - 'Drinking your sugar is more problematic for health than eating it'
1) Dietary Sugar Intake and Incident Type 2 Diabetes Risk: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

DIABETES RISK - VITAMIN D - Vitamin D Helps Balance Blood Sugar & Reduce Type 2 Diabetes Risk. By Morgan Chamberlain, MindBodyGreen, July 21, 2025.
1) Prevalence of Vitamin D Deficiency among Patients with Type 2 Diabetes in Qingdao, China.
2) Vitamin D and type 2 diabetes. (Dr. Paul Lips, Department of Internal Medicine, Endocrine Section, VU University Medical Center, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. p.lips@vumc.nl )

ENVIRONMENT - GREENHOUSE GASES - CARBON DIOXIDE -Physics Demonstrates That Increasing Greenhouse Gases Cannot Cause Dangerous Warming, Extreme Weather Or Any Harm. More Carbon Dioxide Will Create More Food. Driving Greenhouse Gas Emissions to Net Zero and Eliminating Fossil Fuels Will Be Disastrous for People Worldwide. SUMMARY FULL PAPER by
1) Richard Lindzen, PhD, Professor of Earth, Atmospheric, and Planetary Sciences, Emeritus, Massachusetts Institute of Technology
2) William Happer, PhD, Professor of Physics, Emeritus, Princeton University

FIBROMYALGIA - DIET - SUPPLEMENTS - STRESS - SLEEP - EXERCISE - ALTERNATIVE THERAPIES - Fibromyalgia: A Chronic Condition With Widespread Pain—Natural Ways to Relieve It. Fibromyalgia affects how the body processes pain, leading to a range of symptoms. By Mercura Wang, EPOCH Times, July 22, 2025.

INFECTIOUS DISEASE - POST COVID PANDEMIC - Pandemic Aftermath: Why Infectious Diseases Are Surging—And How I’d Treat Myself If I Fell ILL. Here, I do a deep dive into the"mysterious" rise of infectious diseases worldwide—and my straightforward, practical approach to treating infectious illnesses if they were to strike me or my family. Pierre Kory, MD, MPA, Pierre Kory’s Medical Musings Jul 28, 2025.

LIVER DISEASE - CANCER - Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Liver Cancer and Chronic Liver Disease Mortality. “…Findings: In 98 786 postmenopausal women followed up for a median of 20.9 years, compared with consuming 3 servings or less of sugar-sweetened beverages per month, women consuming 1 or more servings per day had significantly higher rates of liver cancer (18.0 vs 10.3 per 100 000 person-years; adjusted hazard ratio [HR], 1.85) and chronic liver disease mortality (17.7 vs 7.1 per 100 000 person-years; adjusted HR, 1.68)…” (Author: Xuehong Zhang, MBBS, ScD, Brigham and Women’s Hospital and Harvard Medical School, 181 Longwood Ave, Room 453, Boston, MA 02115 (xuehong.zhang@channing.harvard.edu).

MITOCHONDRIAL FUNCTION - VISION - SUNLIGHT - NEW STUDY: Sunlight Penetrates the Human Body, Improving Mitochondrial Function and Vision. Just 15 minutes of fully clothed infrared sunlight exposure triggered systemic effects and measurable improvements in vision — even with eyes completely covered. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Jul 14, 2025.
1) Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision.

MITOCHONDRIAL DYSFUNCTION - SSRIs - SSRIs Can Cause Severe Mitochondrial Dysfunction. Installment eight in our series on understanding the truth about SSRIs. Chris Masterjohn, PhD, Harnessing the Power of Nutrients, Jul 29, 2025.

STROKE - HEMORRHAGIC - mRNA Injury Stories - 17 year old VOICE Star Karen Silva dies of hemorrhagic stroke. Dr. William Makis MD, Covid Intel, Aug 01, 2025.

SUDDEN DEATH - UNEXPLAINED - DOCTOR - mRNA Injury Stories - 30 year old Dr.Meliah Blair (Veterinarian) of Newport KY, died unexpectedly at her home on May 11, 2025. Dr. William Makis MD, Covid Intel, Jul 15, 2025.

THYROID FUNCTION - NUTRIENTS - IODINE- SELENIUM- IRON- ZINC- COPPER- MAGNESIUM - VITAMIN A - VITAMIN B12
1) The Role of Nutrition on Thyroid Function

TOXICITY - GLYPHOSATE - CHINA - Why Are We Paying China to Poison Us? And why did Congress just make it harder to fight back? Mollie Engelhart, EPOCH Times, 7/26/2025.

VACCINATION - EFFICACY - AMERICAN ACADEMY OF PEDIATRICS - American Academy of Pediatrics tacitly admits that vaccines don't work! If vaccines worked, vaccinated kids would have NOTHING to fear from unvaccinated kids. So why do we need to protect them? Steve Kirsch, Steve Kirsch's newsletter,
Jul 28, 2025.

Cancer…

BLADDER CANCER - COVID VACCINE - BLOOD CLOTS - After COVID-19 Vaccine Blood Clots, Deion Sanders Hit with Turbo Cancer. Unusual Aggressive Bladder Cancer Reported During Pandemic in Literature. Peter A. McCullough, MD, MPH, Focal Points/Courageous Discourse, Jul 31, 2025.

BLADDER CANCER - COVID-19 VACCINATION - Vaccination and Bladder Cancer Deion Sanders Vaccine Turbo Cancer Brings Issue to Light. Peter A. McCullough, MD, MPH, Aug 02, 2025.

BLADDER CANCER - IVERMECTIN - FENBENDAZOLE - High-Grade Non-Invasive Bladder Cancer, age 69, Male. Surgery, Ivermectin and Fenbendazole. Ben Fen, Jul 27, 2025.
1) Fenbendazole as an Anticancer Agent? A Case Series of Self-Administration in Three Patients.

CANCER RISK - EXERCISE - This Simple Well-Researched Habit Cuts Cancer Death Risk By Nearly 50%. By Ava Durgin, MindBodyGreen, March 10, 2025. “…Could just 60 minutes of moderate exercise per week significantly improve cancer outcomes? According to a study published in the British Journal of Sports Medicine, the answer is a resounding yes?…”
1) Association between recorded physical activity and cancer progression or mortality in individuals diagnosed with cancer in South Africa.

PANCREATIC CANCER - IVERMECTIN and FENBENDAZOLE - 69 year old New York man with Stage 4 Pancreatic Cancer and CA19-9 14934 reports after 2 months. Dr. William Makis MD, Covid Intel, Jul 31, 2025.

PROSTATE CANCER - FENBENDAZOLE - Case Report: Metastatic Prostate Cancer, Liver and Lymph Node Metastases, age 74. Metastatic Stage IV Prostate Cancer Squashed with Fenbendazole. Ben Fen, Jul 29, 2025.

Covid Syndrome…

COVID VACCINATION - BOOSTER - IMMUNE SYSTEM - INFLAMMATION - COAGULATION - mRNA Boosters Trigger Dangerous Immune & Blood Abnormalities Within 48 Hours in Healthy Young Adults. Even without symptoms, mRNA boosters trigger immune suppression, systemic inflammation, and coagulation abnormalities. Nicolas Hulscher, MPH, Focal Point, Courageous Discourse, Jul 28, 2025.
1) Immune and hematologicak responses to the third dose of an mRNA COVID-19 vaccine: a six-month longitudinal study. “…Conclusions: A booster dose with an mRNA vaccine at the recommended time causes the anti-SARS-CoV-2 IgG and IgA levels to increase rapidly and for at least six months. The increase in inflammatory cytokines and changes in the coagulation profile are consistent with the vaccine’s normal immune induction mechanism. Mild AEFIs (adverse events following immunization) were reported in a minority of vaccine recipients. The consistent subclinical changes in inflammatory and coagulation markers suggest that these pathways may be involved in the pathogenesis of severe ARFIs reported with mRNA vaccines…”

COVID VACCINATION - GENETIC DISRUPTION - CANCER- CHRONIC DISEASE - BREAKING STUDY: mRNA Injections Induce Severe, Long-Lasting Genetic Disruption Linked to Cancer and Chronic Disease. Landmark study reveals COVID-19 “vaccines” severely disrupt the expression of thousands of genes—triggering mitochondrial failure, immune reprogramming, and oncogenic activation. Nicolas Hulscher, MPH, Focal Points/Courageous Discourse, Jul 25, 2025.
1) Synthetic mRNA Vaccines and Transcriptomic Dysregulation: Evidence from New-Onset Adverse Events and Cancers Post-Vaccination. “…Conclusions: The observed transcriptomic profiles indicate persistent cellular stress responses, mitochondrial dysfunction, and immune dysregulation following exposure to mRNA vaccines, potentially in susceptible individuals. Shared and distinct molecular signatures in both cohorts demonstrate underlying mechanisms contributing to post-vaccine symptomatology and complications, including oncogenesis and or progression of malignant disease. These findings underscore the need for a deeper investigation into the long-term safety of mRNA vaccines and host response variability…”

COVID VACCINATION - HAIR LOSS - COVID-19 Vaccination — Not Infection — Increases Risk of Multiple Hair Loss Disorders. Massive study of 5.7 million Koreans finds COVID-19 vaccination significantly increases the risk of complete hair loss, patchy autoimmune hair loss, and excessive shedding. Nicolas Hulscher, MPH, Focal Points/Courageous Discourse, Jul 31, 2025.
1) New Onset of Hair Loss Disorders During the Coronavirus Disease 2019 Pandemic: A Korean Nationwide Population-Based Study. “…Conclusion: COVID-19 vaccination was positively correlated with hair loss disorders but not COVID-19 infection…”

COVID VACCINATION - MYOCARDITIS - MRI - Cardiac MRI One Year after COVID-19 Vaccination Valuable in Detecting Heart Damage. Sustained Myocarditis Concerning in Young Persons. Peter A. McCullough, MD, MPH, Focal Points/Courageous Discourse, Jul 27, 2025.
1) Resolution of Refractory COVID-19 Vaccine-Induced Myopericarditis with Adjunctive Rapamycin.
2) Improved diagnosis of COVID-19 vaccine-associated myocarditis with cardiac scarring identified by cardiac magnetic resonance imaging.

COVID VACCINATION -MYOCARDITIS - CARDIAC MRI - Improved diagnosis of COVID-19 vaccine-associated myocarditis with cardiac scarring identified by cardiac magnetic resonance imaging. (Professor Andrew J Taylor, Department of Cardiology, Alfred Hospital, Melbourne, Victoria, Australia / Department of Cardiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia. andrew.taylor2@mh.org.au “…Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) occurred in one-third of patients with COVID-19 vaccine-associated myocarditis (C-VAM). Without CMR at the time of diagnosis, almost one-third of patients are misclassified as probable rather than definite myocarditis, indicating a diagnostic strategy using echocardiography alone is insufficient…”

COVID VACCINATION - SPIKE PROTEIN - NATTOKINASE - Spanish "Vaxtherapy" Positions Nattokinase First Line. Handling Spike Protein as Core Culprit is Primary Goal in Treating Long-Vax Syndromes. Peter A. McCullough, MD, MPH, Focal Points (Courageous Discourse), Jul 30, 2025.
1) Vaxtherapy, a Multiphase Therapeutic Protocol Approach for Longvax, the COVID-19 Vaccine-Induced Disease: Spike Persistence as the Core Culprit and Its Downstream Effects.

COVID VACCINATION - IMMUNE FUNCTION - INFLAMMATION- COAGULATION - mRNA Boosters Trigger Dangerous Immune & Blood Abnormalities Within 48 Hours in Healthy Young Adults. Even without symptoms, mRNA boosters trigger immune suppression, systemic inflammation, and coagulation abnormalities. Nicolas Hulscher, MPH, Focal Points, Courageous Discourse, Jul 28, 2025.
1) Immune and hematologicak responses to the third dose of an mRNA COVID-19 vaccine: a six-month longitudinal study.

POST COVID SYNDROME - BRAIN FOG - COGNITION - This SARS-spike thing they made ruins brains. A new study demonstrates hypometabolism (reduced glucose uptake) in specific areas of the human brain - think reason for brain fog. Jessica Rose, Unacceptable Jessica, Jul 15, 2025.
1) Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing. “…The results showed significant hypometabolism in the bilateral frontal, temporal, and parietal lobes, as well as in the left occipital lobe, along with predominantly frontal EEG slowing in post-COVID-19 patients compared to healthy controls…The observed PET hypometabolism and EEG slowing patterns in anterior brain regions, may help to elucidate the pathophysiological mechanisms underlying cognitive decline in post-COVID-19 patients…”

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Colon Cancer and Vitamin D, Mechanisms in Prevention and Treatment an Interview with Professors János Tamás Varga, MD and Mónika Fekete

Watch Kirk Hamilton PAC’s Video Summary of This Interview Here

Professor János Tamás Varga, MD
Department of Pulmonology, Semmelweis University
1083 Budapest, Hungary
varga.janos.tamas@semmelweis.hu

Mónika Fekete, MD
Institute of Preventive Medicine and Public Health
Faculty of Medicine, Semmelweis University
1089 Budapest, Hungary
fekete.monika@semmelweis.hu

“Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications,”
Nutrients. 2025 Apr 15;17(8):1351 (7/2025)

Kirk Hamilton: Can you please share with me your educational background and current position?

Dr. Mónika Fekete and Prof. János Tamás Varga: The authors of the study are affiliated with various faculties and research institutes of Semmelweis University, primarily working in preventive medicine, nutrition science, immunology, pulmonology, and cardiovascular medicine. Several authors hold medical degrees (MD) and PhDs, and currently serve as educators, researchers, or clinicians within different departments of Semmelweis University (e.g., Department of Preventive Medicine and Public Health, Heart and Vascular Clinic, Department of Rheumatology and Clinical Immunology, Department of Pulmonology). We also collaborate with the HUN-REN Energy Science Research Centre. The corresponding author of the article is Prof. János Varga, Professor at the Department of Pulmonology, Semmelweis University.

KH: What got you interested in studying the role of vitamin D in colorectal cancer prevention and treatment?

MF & JTV: Colorectal cancer (CRC) is one of the most common cancers and causes of cancer-related mortality worldwide. Therefore, research into preventive strategies is of high importance for public health and preventive medicine. The role of vitamin D has gained increasing attention not only for bone metabolism but also for its immunomodulatory and anti-inflammatory effects over the last decade.

Our research group was motivated by the observed epidemiological and clinical associations between vitamin D deficiency and CRC incidence. However, many underlying mechanisms remain unclear. We were particularly interested in exploring the immunological and inflammatory pathways involved, as they play key roles in carcinogenesis and could serve as targets for preventive strategies.

Furthermore, nutritional and lifestyle aspects of vitamin D — such as supplementation optimization and addressing population-wide deficiencies — are especially relevant for public health practice.

KH: What is the mechanism of how vitamin D adequacy may prevent colorectal cancer?

MF & JTV: Vitamin D, especially its active form calcitriol (1,25(OH)₂D₃), regulates multiple cellular processes critical in cancer prevention:

  • Cell differentiation and proliferation inhibition: Activation of the vitamin D receptor (VDR) promotes normal cell differentiation and inhibits excessive cell division, which is crucial in colorectal epithelial cells where dysregulated proliferation can lead to cancer.

  • Promotion of apoptosis: Calcitriol induces programmed cell death in damaged or transformed cells, eliminating potentially cancerous cells.

  • Modulation of inflammatory pathways: Vitamin D suppresses pro-inflammatory cytokines (e.g., IL-6, TNF-α) while promoting anti-inflammatory mediators (e.g., IL-10), which is important given the link between chronic inflammation (such as ulcerative colitis) and CRC risk.

  • Immunomodulation: Vitamin D balances innate and adaptive immunity, enhancing tumor-fighting cytotoxic T cells (CD8⁺) and reducing pro-tumor immune populations (e.g., Th17 cells).

  • Effects on the microbiome: Vitamin D influences gut microbiota composition, which is linked to CRC development by maintaining intestinal barrier function and immune homeostasis.

In summary, vitamin D acts as an active biological regulator through multiple cellular and immunological pathways, contributing to colorectal cancer prevention.

KH: What is the mechanism of how vitamin D may be beneficial as an adjunctive treatment of colon cancer?

MF & JTV: The active form of vitamin D supports CRC therapy through:

  • Antiproliferative effects by activating cell cycle inhibitors (p21, p27) that block tumor cell division.

  • Induction of apoptosis via activation of BAX/BAK pathways.

  • Inhibition of Wnt/β-catenin signaling, crucial in tumor development, and enhancement of E-cadherin and DKK-1 expression.

  • Immunomodulation and reduction of inflammation, including suppression of IL-6 and IL-8.

  • Antiangiogenic effects by decreasing HIF-1α and VEGF levels, inhibiting new blood vessel formation.

  • Potential improvement of chemotherapy response and reduction of recurrence risk, particularly with optimal serum vitamin D and micronutrient levels (e.g., magnesium).

Thus, vitamin D has complex cellular and immune effects that make it a promising adjuvant in personalized combined CRC treatment.

KH: What role does vitamin D adequacy play in the prevention of recurrence of colorectal cancer?

MF & JTV: Increasing evidence suggests adequate vitamin D levels are important not only in preventing CRC onset but also in reducing recurrence and progression. Calcitriol’s immunomodulatory, anti-inflammatory, cell cycle inhibitory, and pro-apoptotic effects may suppress residual tumor cells and prolong cancer-free survival.
Several clinical studies support this:

Although not all studies showed significant differences, overall data suggest vitamin D supplementation—especially achieving optimal serum levels—may reduce recurrence risk and improve survival, influenced by individual factors like BMI, magnesium intake, and baseline vitamin D status.

KH: What is a “preventive” blood level of vitamin D3?

MF & JTV: The preventive blood level refers to the optimal serum 25-hydroxyvitamin D concentration associated with reduced risk of CRC development and recurrence. Current literature generally accepts a minimum level of 30 ng/ml (75 nmol/L), above which protective effects increase.

Some studies suggest levels of 36–40 ng/ml (90–100 nmol/L) may offer even stronger protection. Levels below 30 ng/ml indicate insufficiency or deficiency, associated with higher cancer and chronic disease risk.

It is important to avoid excessively high levels (>100 ng/ml or 250 nmol/L), which pose health risks such as hypercalcemia.
In summary:

  • Minimum recommended: ≥ 30 ng/ml (75 nmol/L)

  • Optimal/preventive range: 36–40 ng/ml (90–100 nmol/L)

  • Potentially harmful level: > 100 ng/ml (250 nmol/L)

Individual needs and health status should guide supplementation, with medical supervision and regular monitoring.

KH: There is debate about the optimal serum level of vitamin D for cancer prevention, treatment and recurrence prevention. You leave a wide gap from ”Optimal” 36-40 ng/ml and ”Potentially harmful” > 100 ng/ml of 40-100 ng/ml? As a health practitioner who has done 1000s of vitamin D levels on patients I have never seen side effects under 100 ng/ml (unless they have parathyroid or kidney disease) and I see people taking 5000 IU routinely of vitamin D3 getting into the 30-50 ng/ml range. Personally for general health reasons and as someone who has had colon cancer I try and keep my vitamin D levels between 50-75 ng/ml. That takes about 10,000 IU per day 5-7 days per week. A 2000 IU/d dose for an adult seems to be low in my clinical experience to get levels even to 30 ng/ml? To me toxic side effects between 30-100 ng/ml are not an issue. What needs to be done is doses studied between 5000-10,000 IU per day to a get level between 50-100 ng/ml to see if there really is clinical benefit in colon cancer prevention, treatment and cancer recurrence.

1. Vitamin D Page 73 https://imahealth.org/wp-content/uploads/2023/06/Cancer-Care-FLCCC-Dr-Paul-Marik-v2.pdf

2. Vitamin D: Evidence-Based Health Benefits and Recommendations for Population Guidelines

You may have already addressed this in your answers above but do you have any additional comments on higher doses of vitamin D for prevention, adjunctive cancer treatment and prevention of cancer recurrence?

MF & JTV: Thank you for the thoughtful comments and clinical insights. We agree that the currently accepted optimal serum levels of vitamin D are indeed debated, particularly in oncology. While most population guidelines (including those from WHO and national authorities) define 30–50 ng/mL as a safe and physiologically sufficient range, some clinical observations — especially in cancer patients or those at high risk — suggest that higher levels (e.g., 50–75 ng/mL) might be beneficial.

However, it is important to note that vitamin D is a fat-soluble vitamin that accumulates in the body over time. Therefore, from a public health and safety standpoint, most national and international recommendations define 4000 IU/day as the tolerable upper intake level for healthy adults. Exceeding this level chronically may increase the risk of adverse events (e.g., nephrocalcinosis or hypercalcemia), especially in individuals with comorbidities or genetic susceptibilities.

In the SUNSHINE clinical trial — one of the most relevant interventional studies in metastatic colorectal cancer — patients received a bolus dose of 8000 IU/day only for the first 2 weeks, followed by 4000 IU/day as maintenance, confirming that even in oncology settings, long-term very high doses are typically avoided. PubMed link: https://pubmed.ncbi.nlm.nih.gov/30964527/

We fully acknowledge your clinical experience and agree that doses between 5000–10,000 IU/day may be necessary in certain cases (e.g., high BMI, limited sunlight exposure) to achieve higher serum levels. However, the long-term safety of sustained serum levels above 75–100 ng/mL still requires rigorous, randomized controlled trials, particularly in oncology.

Please note that we are not clinical oncologists, and in our article we approached the topic of vitamin D supplementation from a public health and preventive medicine perspective, not as a cancer treatment protocol. The SUNSHINE trial itself used only a short-term loading dose of 8000 IU/day followed by a maintenance dose of 4000 IU/day, which aligns with the globally recognized safe upper limit.

KH: What is a good blood level of vitamin D to achieve while someone is being treated for colon cancer?

MF & JTV: For CRC patients undergoing treatment, maintaining an optimal 25(OH)D level between 30–50 ng/ml (75–125 nmol/L) is advised. This range is associated with improved survival, reduced recurrence risk, and favorable effects on immune function and inflammation.
Evidence includes:

  • Epidemiological data linking serum 25(OH)D above 30 ng/ml to better prognosis and lower recurrence.

  • Hormonal effects of vitamin D that support anti-cancer mechanisms and enhance treatment efficacy.

  • Clinical practice recommends individualized supplementation with regular blood level monitoring, considering factors such as body weight, ethnicity, and ongoing therapies.

  • Avoiding toxic levels (>100 ng/ml) is crucial to prevent hypercalcemia.
    Monitoring and maintaining appropriate vitamin D status is part of comprehensive cancer care to improve quality of life and outcomes.

KH: Can you tell us about your study and the basic results?

MF & JTV: Our study, titled “Vitamin D and Colorectal Cancer Prevention: Immunological Mechanisms, Inflammatory Pathways, and Nutritional Implications,” aimed to provide a comprehensive overview of vitamin D’s role in CRC prevention, focusing on immunological mechanisms, inflammatory pathways, and nutritional aspects.
We performed a literature review analyzing vitamin D’s various effects on CRC risk reduction. Key highlights include:

  • The active form, 1,25-dihydroxyvitamin D3, regulates tumor cell proliferation, promotes differentiation, and induces apoptosis, thereby inhibiting tumor growth.

  • Vitamin D modulates inflammatory signaling pathways (e.g., NF-κB, IL-6, TNF-α) critical in CRC pathogenesis.

  • Maintaining adequate vitamin D levels through sunlight exposure, diet, and supplementation is important for CRC prevention.

  • Epidemiological and clinical data collectively suggest that optimal 25(OH)D levels can reduce CRC incidence and improve survival.

  • We emphasize regular monitoring of vitamin D status, especially in high-risk populations.

Overall, our study supports that vitamin D plays a key role beyond bone health, acting through immune and inflammatory regulation to contribute to primary CRC prevention.

KH: Is there an advantage of vitamin D levels attained by being in the sun versus by vitamin D taken by mouth? Said differently, is there something from sun exposure that may additionally be beneficial for the prevention or treatment of colon cancer?

MF & JTV: Vitamin D levels can be raised both through skin synthesis triggered by sunlight exposure (UV-B radiation) and by oral vitamin D supplementation. However, vitamin D production via sunlight may have certain advantages. The synthesis of vitamin D3 in the skin is regulated by natural feedback mechanisms that limit excessive vitamin D formation, thereby reducing the risk of vitamin D toxicity. This regulation aligns with kidney-based control processes and represents the skin’s natural protective mechanism.

Moreover, UV radiation itself exerts multiple beneficial biological effects that may contribute to colorectal cancer prevention and treatment. Some studies have shown that sun exposure has positive immunomodulatory effects and promotes anti-inflammatory processes, which play important roles in slowing cancer progression. Vitamin D additionally induces apoptosis in certain cancer cell lines, including colorectal cancer cells, making the maintenance of adequate vitamin D levels crucial.

At the same time, sun exposure must be kept within safe limits to avoid the risk of skin cancer caused by excessive UV radiation. Proper photoprotection and avoiding sunburn maximize the benefits of sunlight-driven vitamin D synthesis. When UV exposure is limited—due to season, latitude, or other factors—oral vitamin D supplementation remains an effective and safe alternative.

In summary, vitamin D derived from sun exposure is advantageous not only due to its natural regulatory mechanisms but also because of the additional immune- and inflammation-modulating effects of UV radiation, which may contribute to colorectal cancer prevention and treatment. Achieving optimal effects requires both safe sun exposure practices and medically supervised vitamin D supplementation.

KH: How important is vitamin D as a single nutrient/hormone in the prevention, treatment, and prevention of recurrence of colon cancer?

MF & JTV: Vitamin D plays a significant role as a single nutrient and hormone in the prevention, treatment, and prevention of recurrence of colorectal cancer. Numerous epidemiological and clinical studies have demonstrated that maintaining adequate serum 25(OH)D levels—generally above 30 ng/mL (75 nmol/L)—is associated with a reduced risk of colorectal cancer and improved survival outcomes in patients.

Mechanistically, the active form of vitamin D, calcitriol (1,25-dihydroxyvitamin D3), exerts multiple cellular effects that directly influence tumor progression. It promotes apoptosis of cancer cells, inhibits proliferation, reduces inflammation, and supports the effective functioning of the immune system. These actions are key not only in preventing tumor development but also in treating existing tumors and decreasing the risk of disease recurrence.

However, it is important to note that colorectal cancer is a complex disease influenced by numerous genetic, environmental, and lifestyle factors. Therefore, vitamin D should not be regarded as a standalone “miracle cure” but rather as part of a comprehensive preventive and therapeutic strategy that includes appropriate lifestyle, nutrition, and medical treatment.

In summary, vitamin D is a key nutrient and hormone in colorectal cancer prevention, treatment, and recurrence prevention, but its effectiveness is best realized within a multidisciplinary approach.

KH: Do you have any further comments on this interesting topic?

MF & JTV: Raising serum 25-hydroxyvitamin D levels above 30 ng/mL (75 nmol/L) can significantly contribute—based on many epidemiological and clinical studies—to reducing the risk of chronic diseases, including colorectal cancer. Higher vitamin D levels have also been associated with decreased mortality from conditions such as cardiovascular disease, stroke, diabetes, and respiratory infections.

Currently, vitamin D supplementation is the most effective and controllable method to achieve and maintain the desired 25(OH)D concentration, especially when sunlight-driven synthesis is limited. The optimal minimal daily dose for healthy adults with normal body weight is approximately 2000 IU (50 µg), which allows reaching serum levels of 30–40 ng/mL with minimal safety risks. Supplementation can be administered daily, weekly (e.g., 15,000 IU), or monthly (e.g., 60,000 IU), with weekly or monthly dosing often improving patient compliance.

Loading doses (“bolus”) given in the first one or two weeks can rapidly raise vitamin D levels, while lower doses maintain a stable concentration over time. This approach enables personalized supplementation, considering the patient’s baseline vitamin D status, lifestyle, and risk factors.

In Hungary, according to the updated 2022 “Hungarian Consensus Recommendation on the Role of Vitamin D in Disease Prevention and Treatment,” recommended vitamin D intake varies by age group. The goal is to maintain serum levels around or above 30 ng/mL, which may contribute long-term to colorectal cancer prevention, treatment, and reduction of recurrence risk.

Additionally, some recent publications highlight vitamin D3 supplementation’s potential benefits in anti-aging and general health maintenance: https://www.independent.co.uk/news/science/vitamin-d3-daily-anti-ageing-b2757496.html 

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